Computational Personalised Medicine
We are currently working on the following medically relevant topics:
- In vitro fertilisation (PHRT-funded) & Early Embryogenesis
- Lung Morphometrics in Health and Disease based on CT images
- Digital Pathology
The Personalised Health and Related Technologies initiative (external page PHRT) has provided us with funding for the following 3 topics:
1. Bladder Cancer: external page Morphometric analysis of epithelial bladder cancer progression (PhD student: Franziska Lampart)
2. Prostate Cancer: external page Personalizing treatment of prostate cancer with image-based diagnostics informed by deep learning and physics-based models (Post-Doc: Dr Kevin Yamauchi)
3. In vitro fertilisation:
- iDoc grant: external page Optimising IVF Outcome with a Computational Personalised Medicine Approach (PhD student: Leopold Franz)
- Reserach grant: Personalized Ovarian Stimulation Protocols: A Translational Medicine Approach for Optimizing Fertility Outcomes (PROSPECT- study) (Collaborators: Christian De Geyter (Uni Basel), Susanne Ulbrich (USYS, ETHZ)) Open Post-Doc position

Morphometry and mechanical instability at the onset of epithelial bladder cancer
Lampart FL , Vetter R, Yamauchi KA, Wang Y, Runser S, Strohmeyer N, Meer F, Hussherr MD, Camenisch G, Seifert HH, Rentsch CA, Le Magnen C, Müller DJ, Bubendorf L, and Iber D external page Nature Physics (2025), external page News & Views, external page Tweetorial, ETH Globe, external page Youtubeexternal page external page

The first two blastomeres contribute unequally to the human embryo
Sergi Junyent, Maciej Meglicki, Roman Vetter, Rachel Mandelbaum, Catherine King, Ekta M. Patel, Lisa Iwamoto-Stohl, Clare Reynell, Dong-Yuan Chen, Patrizia Rubino, Nabil Arrach, Richard J. Paulson, Dagmar Iber and Magdalena Zernicka-Goetz external page Cell(2024)

FollicleFinder: automated three-dimensional segmentation of human ovarian follicles
Yamauchi K, Biniasch M, Franz L, Gomez H, De Geyter C, Iber D
external page bioRxiv (2022), external page Tweetorialexternal page