BEL collaboration with Roska Group yields paper in "Neuron"

High-density microelectrode arrays developed by BEL were used to study neuronal circuit asymmetry and its role in the pathophysiology of nystagmus, a neurological disease, as recently published in Neuron.

Enlarged view: Neuron_Article_BEL_FMI
Data recorded with high-density microelectrode arrays: polar plots showing the preferred directions of individual direction-selective cells in wild type and FRMD7 retinae.

Michele Fiscella, Jan Müller, and Felix Franke collaborated with the Roska group at external page FMI in a large-scale investigation, which identified the FRMD7 gene as a key regulator in establishing neuronal circuit asymmetry and which suggested the involvement of a specific inhibitory neuron type in the pathophysiology of external page nystagmus, a neurological disease. The corresponding research article entitled "Congenital nystagmus gene FRMD7 is necessary for establishing a neuronal circuit asymmetry for direction selectivity" was published in Neuron (2016, 89(1), 177-193).

external page Neuron has established itself as one of the most influential and relied upon journals in the field of neuroscience and serves as one of the premier intellectual forums for the entire neuroscience community.

external page Neuron article

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