Laboratory for Systems and Synthetic Immunology

Search

EN

Laboratory for Systems and Synthetic Immunology

: Overview and News

Laboratory for Systems and Synthetic Immunology

LSSI’s overall research interests are in the emerging fields of systems and synthetic immunology, which are at the intersection of genomics, molecular biotechnology, and immunology.

Systems immunology aims to gain a more comprehensive and quantitative understanding of immune responses using both experimental and computational methods such as high-throughput DNA sequencing and AI. Synthetic immunology applies molecular and cellular engineering methods to reprogram immune cells for the purpose of controlling immunity. Methods consist of directed evolution-protein engineering and targeted genome editing.

LSSI’s core mission is to use immunogenomics and immune cell reprogramming for applications in biotechnology, vaccination, and immunotherapy.

News

BSSE spinoff Engimmune raises seed financing to develop novel T-cell receptor therapeutics

Exciting news from our youngest spinoff company: Engimmune Therapeutics completed a CHF 15.5 million seed financing round to boost R&D of novel T-​cell receptor (TCR)-​based therapeutics. Proceeds from the financing will be used to further build Engimmune’s pipeline, expand the research team in Switzerland and build a foothold in Denmark, with a focus on GMP-​certified manufacturing, clinical development, and regulatory affairs.

In this global pandemic D-BSSE is capable of tackling every aspect

The startup community is hit particularly hard by the global COVID-​19 pandemic. The D-​BSSE spinoff deepCDR Biologics is making the best out of this extraordinary situation - and realises that the pandemic provides the perfect platform to showcase the deepCDR technology and antibody discovery and development. Interview with the co-​founder Derek Mason.

Botnar Research Centre launches research activities

The Botnar Research Centre for Child Health (BRCCH) announces its first four multi-​investigator projects and thus the start of its research activities. D-​BSSE professor Randall Platt will have the lead of a project which aims to develop a CRISPR-​based technology involving engineered bacteria which are capable of sensing, remembering, and reporting on the environment within the gut.

See more news