Conference Contributions

2024

A. Marishi, X. Xue, T. Gänswein, S. Kumar, F. Cardes, F. Freudenberg, A. Hierlemann, "Developmental network topology and electrophysiological disruptions induced by NOS1AP overexpression in in-vitro neuronal networks", Cold Spring Harbor Laboratory Meeting on Development & 3D Modeling of the Human Brain, December 9-12, 2024, Cold Spring Harbor, New York, USA. external page Online

L. Sadiraj, M. Magni, A. Marishi, E. Frattini, A. Hierlemann, A. Di Fonzo, M. Schröter "Functional characterization of hiPSC-derived striatal organoids from dystonia patients using high-density microelectrode arrays", Cold Spring Harbor Laboratory Meeting on Development & 3D Modeling of the Human Brain, December 9-12, 2024, Cold Spring Harbor, New York, USA. external page Online

C.-V. H. Bui, H. Ulusan, A. Hierlemann, F. Cardes, "Nano-volcano electrodes post-fabricated on CMOS microelectrode arrays: towards large-scale intracellular neural interfaces", NanoBioTech Montreux, November 10-13, 2024, Montreux, Switzerland. external page Online

C. Sampaio da Silva, J. A. Boos, M. M. Modena, S. S. Kumar, C. Beyer, T. Valentin, A. Hierlemann, V. Revol, "Electrical impedance spectroscopy platform for label-free characterization of microtissues with facing electrodes", NanoBioTech Montreux, November 10-13, Montreux, Switzerland. external page Online

M. Murdeu, V. Kissling, J. Folz, A. Hierlemann, J.A. Boos, T. Buerki-Thurnherr, "Human-based placenta-embryo chip for developmental toxicity assessment of nanoparticles and drugs" European Placenta Group meeting (EPG), November 7-8, 2024, Hradec Králové, Czech Republic. external page Online

O. Chaliotis, J.A. Boos, M. Ketterer, C. Dehio, A. Hierlemann, "Microphysiological models of the human placenta to study Brucella infections and antibiotic treatment during pregnancy", European Placenta Group meeting (EPG), November 7-8, 2024, Hradec Králové, Czech Republic. external page Online

Invited: A. Hierlemann, "CMOS microelectrode arrays for functional characterization of neuronal preparations at subcellular resolution", 28^th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 10-14, 2024, Montreal, Canada. external page Online

C. Sampaio da Silva, J. A. Boos, M. M. Modena, S. S. Kumar, C. Beyer, T. Valentin, A. Hierlemann, V. Revol, "Electrical impedance spectroscopy platform for label-free characterization of spheroid viability", IEEE Sensors, October 20-24, 2024, Kobe, Japan. external page Online

A. Bultena, A, Kurmashev, J. A. Boos, W. Wei, M. M. Modena, F. Cardes, A. Hierlemann, "Microfluidic platform for real-time impedance profiling of transwell-based barrier models", IEEE Sensors, October 20-24, 2024, Kobe, Japan, Abstract 6427. external page Online

T. Gänswein, H. Ulusan, F. Cardes, A. Hierlemann, S. S. Kumar, J. Bartram, "Studying the interplay between network activity and connectivity in ASD mouse models", 53rd Annual Meeting of the Society for Neuroscience, October 5-9, 2024, Chicago, Illinois, USA. Abstract LBA001.036. external page Online

S. S. Kumar, T. Gänswein, A. Hierlemann, "Activity-dependent variability of extracellular spike shapes", 53rd Annual Meeting of the Society for Neuroscience, October 5-9, 2024, Chicago, Illinois, USA. Abstract LBA009.034. external page Online

T. van der Molen, A. Spaeth, M. Chini, S. Hernandez, G. Kaurala, H. Schweiger, J. Bartram, K. Bhaskaran-Nair, L. Blauvelt, L. Petzold, P. Hansma, M. Teodorescu, A. Hierlemann, K. Hengen, I. Hanganu-Opatz, K. Kosik, T. Sharf, "Protosequences in brain organoids model intrinsic states in the developing cortex", 53rd Annual Meeting of the Society for Neuroscience, October 5-9, 2024, Chicago, Illinois, USA, Abstract PSTR151.19. external page Online

C. Nunes, M. Pascual Garcia, A. Chernov, M. Francisco, E. Harde, A. Hierlemann, M. Schröter "Human-derived RETT syndrome electrophysiology and molecular phenotypic screening platform for the development of new therapies", 53rd Annual Meeting of the Society for Neuroscience, October 5-9, 2024, Chicago, Illinois, USA, Abstract PSTR260.12. external page Online

M. Pascual-Garcia, C. Nunes, P. Hornauer, M. Francisco, A. Chernov, E. Harde, A. Hierlemann, M. Schröter "Exploring the pathopysiology of Rett syndrome: insights from in vitro models and electrophysiological analysis", 53rd Annual Meeting of the Society for Neuroscience, October 5-9, 2024, Chicago, Illinois, USA, Abstract PSTR260.04. external page Online

L. Sadiraj, M. Magni, E. Frattini, A. Hierlemann, A. Di Fonzo, M. Schröter "Assessing striatal organoid models from dystonia patients: functional validation and characterization using high-density microelectrode arrays", 37th ECNP Congress, September 21-24, 2024, Milan, Italy. external page Online

A. Marishi, X. Xue, T. Gänswein, S. Kumar, F. Cardes, F. Freudenberg, A. Hierlemann, "NOS1AP Overexpression impacts network-level electrophysiology and functional connectivity in in-vitro neuronal networks", 37th ECNP Congress, September 21-24, 2024, Milan, Italy. external page Online

M. Pascual-Garcia, C. Nunes, P. Hornauer, M. Francisco, A. Chernov, E. Harde, A. Hierlemann, M. Schröter, "Multimodal screening to explore neuronal dysfunction in Rett syndrome", ZNZ Symposium, September 12, 2024, Zürich, Switzerland external page Online

L. Sadiraj, M. Magni, A. Marishi, E. Frattini, A. Hierlemann, A. Di Fonzo, M. Schröter "Large-scale electrophysiological characterisation of striatal brain organoids derived from dystonia patients", ZNZ Symposium, September 12, 2024, Zürich, Switzerland. external page Online

M. Murdeu, A. Hierlemann, J.A. Boos, T. Buerki-Thurnherr,"Human-based placenta-embryo chip for developmental toxicity assessment of nanoparticles and drugs" International Federation of Placenta Association Conference (IFPA), September 2-6, 2024, Montreal, Canada. external page Online

C.-V. H. Bui, H. Ulusan, A. Hierlemann, F. Cardes, "Scalable 3D Nano-Electrodes Post-Fabricated on CMOS Microelectrode Arrays for Advanced Neural Interfaces", Biointerfaces International Conference, August 20-23, 2024, Muttenz, Switzerland. external page Online

Invited: A. Hierlemann, "Integrated CMOS microsystems for multifunctional characterization across scales", 9th International Summer School on Neuroengineering, July 10-14, 2024, Genova, Italy. external page Online

P. Hornauer, A. Hierlemann, M. Schröter, "Interneuron activity shapes network bursts in vitro", 9th International Summer School on Neuroengineering, July 10-14, 2024, Genova, Italy. external page Online

D. Akarca, A. Dunn, P. Hornauer, S. Ronchi, M. Fiscella, C. Wang, M. Terrigno, R. Jagasia, P. Vértes, S. Mierau, O. Paulsen, S. Eglen, A. Hierlemann, D. Astle, M. Schröter, "Homophilic wiring principles underpin  neuronal network topology in vitro", ISSCR 2024, July 10-13, 2024, Hamburg, Germany. external page Online

M. Murdeu, A. Hierlemann, J.A. Boos, T. Buerki-Thurnherr, "Human-based placenta-embryo chip for developmental toxicity assessment of nanoparticles" European Organs on a Chip Society Conference (EUROoCS), July 3-5, 2024, Milano, Italy. external page Online

M. Stano, C. M. Vetter, B. Kritzer, A. Hierlemann, J. Nazarian, M. M. Modena, "In-vitro determination of 5-aminolevulinic-acid-treatment efficacy in patient-derived DIPG models”, International Symposium on Pediatric Neuro-Oncology, June 28 - July 2, 2024, Philadelphia, PA, USA. (DOI: 10.1093/neuonc/noae064.122). external page Online  

J. B. Petr, M.-S. Lin, A. Hierlemann, M. Baumgartner, M. M. Modena, "PHIROS: A microfluidic platform for long-term, high-resolution imaging of organotypic tissue slices to study astrocyte dynamics", BaCell 3D, June 24-26, 2024, Basel, Switzerland. external page Online

M. Stano, C. M. Vetter, B. Kritzer, A. Hierlemann, J. Nazarian, M. M. Modena. "In-vitro determination of 5-aminolevulinic-acid-treatment efficacy in patient-derived DIPG models”, BaCell 3D, June 24-26, 2024, Basel, Switzerland. external page Online

Wei Wei, B. Kritzer, J. Nazarian, A. Hierlemann and M. Modena, "A perfused, parallelized blood-brain-barrier platform for permeation and efficacy investigations", BaCell 3D, June 24-26, 2024, Basel, Switzerland. external page Online

A. Kurmashev, J. A. Boos, B-J. Laventie, A. L. Swart, R. Sütterlin, T. Junne, U. Jenal, A. Hierlemann, "High-resolution imaging platform to unravel pathophysiological mechanisms of pseudomonas aeruginosa infections of the human upper airway epithelium", BaCell 3D, June 24-26, 2024, Basel, Switzerland. external page Online

O. Chaliotis, J.A. Boos, M. Ketterer, C. Dehio, A. Hierlemann, "Microphysiological models of the human placenta to study Brucella infections and antibiotic treatment during pregnancy", BaCell 3D, June 24-26, 2024, Basel, Switzerland. external page Online

M. Murdeu, A. Hierlemann, J.A. Boos, T. Buerki-Thurnherr, "Human-based placenta-embryo chip for developmental toxicity assessment of nanoparticles and drugs", European Placenta Perfusion Workshop (EPPW), June 13-14, 2024, Rotterdam, The Netherlands. external page Online

O. Chaliotis, J.A. Boos, M. Ketterer, C. Dehio, A. Hierlemann, "Microphysiological model of the placental barrier to study human Brucella infections and antibiotic treatment during pregnancy", MPS World Summit, June 10-14, 2024, Seattle, Washington, USA. Abstract 87 (DOI: 10.58847/ap.2401). external page Online

J. B. Petr, M.-S. Lin, A. Hierlemann, M. Baumgartner, M. M. Modena, "PHIROS: A microfluidic platform for long-term, high-resolution imaging of organotypic tissue slices to study astrocyte dynamics", MPS World Summit, June 10-14, 2024, Seattle, Washington, USA. Abstract 243 (DOI: 10.58847/ap.2401). external page Online

M. Stano, M. Ozdas, S. Brüningk, B. Kritzer, J. Nazarian, A. Hierlemann, M. M. Modena, "Advanced microfluidic platform for in-vitro sonodynamic therapy testing in diffuse midline glioma cell models”, MPS World Summit, June 10-14, 2024, Seattle, Washington, USA. Abstract 532 (DOI: 10.58847/ap.2401). external page Online

A. Kurmashev, J. A. Boos, B-J. Laventie, A. L. Swart, R. Sütterlin, T. Junne, U. Jenal, A. Hierlemann, "High-resolution imaging platform to unravel pathophysiological mechanisms of pseudomonas aeruginosa infections of the human upper airway epithelium", MPS World Summit, June 10-14, 2024, Seattle, Washington, USA, Abstract 204 (DOI:10.58847/ap.2401). external page Online

S. Yan, B. Ciraulo, D. Jovanovic, M.-S. Lin, J. B. Petr, D. Hochuli1, Ö. Özalp, V. A. Alvarez, S. Neuhauss, A. Allalou, M. M. Modena, M. Baumgartner, "Image-based screening reveals tumor-suppressive effects of the neuroprotective agent prostetin/12k in medulloblastoma." Brain Tumor Meeting, May 23-24, 2024, Max Delbrück Center Berlin, Germany. external page Online

T. Gänswein, A. Hierlemann, S. S. Kumar, J. Bartram, "Investigating the interplay between circuit topology and network activity in neurodevelopmental disorders", Lake Conferences - The Neurobiology of Mental Health, May 12-16, 2024, Thun, Switzerland. external page Online

F. Franke, M. Büttner, M. Znidaric, F. Rosselli, B. Roska, A. Hierlemann, A. Bucci, "Axonal pathways and propagation speeds in the human retinal nerve fiber layer. Does speed compensate for length?", ARVO Annual Meeting, May 5-9, 2024, Seattle, USA. external page Online

L. D. Dodi, S. S. Kumar, E. Grünblatt, A. Hierlemann, “Investigating ADHD biomarkers using hiPSC-derived neurons on MEAs”, 4th In-Vitro 2D & 3D Neuronal Networks Summit (MxW Summit 2024), April 8-10, 2024, Zurich, Switzerland. external page Online

M. Pascual-Garcia, C. Nunes, M. Francisco, A. Chernov, E. Harde, A. Hierlemann, M. Schröter "Unraveling neuronal dysfunction in Rett syndrome: insights from a multimodal phenotypic screening approach", 4th In-Vitro 2D & 3D Neuronal Networks Summit (MxW Summit 2024), April 8-10, 2024, Zurich, Switzerland. external page Online

J. Bartram, F. Jüngling, T. Gänswein, H. Ulusan, F. Cardes, S. S. Kumar, A. Hierlemann, "High-throughput and consistent HD-MEA recordings of acute neural tissue preparations", 4th In-Vitro 2D & 3D Neuronal Networks Summit (MxW Summit 2024), April 8-10, 2024, Zurich, Switzerland. external page Online

C. Nunes, A. Chernov, M. Pascual Garcia, M. Francisco, E. Harde, A. Hierlemann, M. Schröter, " Human ESC-derived RETT syndrome electrophysiology and molecular phenotypic screening platform for the development of new therapies", iPSZürich 2024 Symposium, April 4-5, 2024, Zurich, Switzerland. external page Online

L. D. Dodi, S. S. Kumar, E. Grünblatt, A. Hierlemann, “Investigating ADHD biomarkers using hiPSC-derived neurons on MEAs”, iPSCZürich 2024 Symposium, April 4-5, 2024, Zurich, Switzerland. Abstract 8. external page Online

T. Häfeli, S. Riss, C. Lohasz, D. Hasanova, S. Lützow, L. Hölting, M. Rudnik, F. Linke, W. van Weerden, L.-A. Ligeon, A. Hierlemann, M. Modena, O. Frey, "Assessment of immune cell infiltration and cancer metastatic potential in Akura™ immune flow chip - a microfluidic 3D spheroid system", AACR Annual Meeting 2024, March 22, 2024, San Diego, USA and Cancer Research 2024, Vol. 84 (6 Supplement), Abstract 6786. external page Online

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2023

I. Sorg, M. U. Girgin, L. Grassi, A. Kurmashev, J. A. Boos, A. Hierlemann, C. Dehio, "Development of bladder organoid model to study live UPEC infections", AMR Conference, March 16-17, 2023, Basel, Switzerland. external page Online

L. Grassi, I. Sorg, C. Flores, A. Kurmashev, J. A. Boos, M. U. Girgin, S. Klimke, S. T. Sutter, A. Hierlemann, C. Dehio, "A human bladder microtissue model to study uropathogenic Escherichia coli infection at high resolution", BaCell 3D Conference, May 8-9, 2023, Basel, Switzerland. external page Online

Invited: A. Hierlemann, "Microphysiological systems featuring microfluidic and microsensor structures", BaCell 3D Conference, May 8-9, 2023, Basel, Switzerland. external page Online

O. Chaliotis, J. A. Boos, C. Dehio, A. Hierlemann, "Microphysiological model of the placental barrier to study human Brucella infections and antibiotic treatment during pregnancy", NCCR AntiResist Annual Retreat, May 22-24, 2023, Sursee, Switzerland.

L. Grassi, I. Sorg, C. Flores, A. Kurmashev, J. A. Boos, M. U. Girgin, S. Klimke, S. T. Sutter, A. Hierlemann, C. Dehio, "Development of a Bladder Organoid Model to study live UPEC infections", NCCR AntiResist Annual Retreat, May 22-24, 2023, Sursee, Switzerland.

A. Kurmashev, J. A. Boos, A. Hierlemann, "Microfluidic platform for transwell-based upper airway cultures under alternating air-liquid and liquid-liquid interface conditions", NCCR AntiResist Annual Retreat, May 22-24, 2023, Sursee, Switzerland.

M. Murdeu, A. Hierlemann, J. Boos, T. Buerki-Thurnherr, "Human based placenta-embryo chip for developmental toxicity assessment of nanoparticles", European Placenta Perfusion Workshop, June 15-18, 2023, Graz, Austria.

A. Kurmashev, J. A. Boos, A. Hierlemann, "Microfluidic platform for transwell-based upper airway cultures under alternating air-liquid and liquid-liquid interface conditions", 2nd Microphysiological Systems World Summit (MPS World Summit), June 26-30, 2023, Berlin, Germany. Abstract 220 (DOI: 10.58847/ap.2301) external page Online

M. Murdeu, A. Hierlemann, J. Boos, T. Buerki-Thurnherr, "Human based placenta-embryo chip for developmental toxicity assessment of nanoparticles", 2nd Microphysiological Systems World Summit (MPS Summit), June 26-30, 2023, Berlin, Germany. Abstract 214 (DOI: 10.58847/ap.2301) external page Online

J. B. Petr, M-S. Lin, P. Machado Almeida, A. Hierlemann, M. Baumgartner, M. M. Modena, "Dynamic platform for continous, high-resolution imaging of organotypic brain-tissue slices", 2nd Microphysiological Systems World Summit (MPS World Summit), June 26-30, 2023, Berlin, Germany. Abstract 368 (DOI: 10.58847/ap.2301). external page Online

J. Boos, I. Wegner, A. Hierlemann, "Integration of human-stem-cell-based embryoid bodies into a microfluidic multi-tissue platform for systemic embryotoxicity testing", 2nd Microphysiological Systems World Summit (MPS Summit), June 26-30, 2023, Berlin, Germany. Abstract 623 (DOI: 10.58847/ap.2301) external page Online

Invited Plenary: A. Hierlemann, "Microphysiological systems with integrated biosensors", IEEE Biosensors, July 30 - August 1, 2023, London, UK. external page Online

H. Ulusan, R. Diggelmann, J. Bartram, C. Magnan, S. Kumar, A. Hierlemann, "Multi-functional HD-MEA platform for high-resolution impedance imaging and electrophysiological recordings of brain slices", IEEE Biosensors, July 30 – Aug 1, 2023, London, UK. external page Online

M. Murdeu, A. Hierlemann, J. Boos, T. Buerki-Thurnherr, "Completing placental perfusion with a human-based placenta-embryo chip model", International Federation of Placenta Association (IFPA) Conference, September 5-8, 2023, Rotorua, New Zealand, external page Online

C. Sampaio da Silva, C. Beyer, J. Boos , S. Kumar, M. Modena, T. Valentin, A. Hierlemann, and V. Revol, "Sensitivity characterization of an impedance-based platform for viability analysis of 3D spheroids", Eurosensors XXXIV, September 10-13, 2023, Lecce, Italy. external page Online

C.-V. H. Bui, N. Maliakal, H. Ulusan, A. Hierlemann, F. Cardes, "A low-cost testbed for neural microelectrodes", Eurosensors XXXIV, September 10-13, 2023, Lecce, Italy. external page Online

M-S. Lin, J. B. Petr, D. Hochuli, P. Machado Almeida, A. Hierlemann, M. M. Modena, M. Baumgartner, "Visualization of cellular dynamics and anti-tumor drug responses using a perfused cerebellar tissue-tumor co-culture model", European Association for Cancer Research (EACR) Conference: Goodbye Flat Biology: Next Generation Cancer Models, October 10-12, 2023, Berlin. Germany. external page Online

A. Kurmashev, J. Boos, B. Laventie, L. Swart, R. Sütterlin, T. Junne, U. Jenal, A. Hierlemann, "Transwell-based microphysiological platform for high-resolution imaging of airway tissues", 12th Basel Postdoc Network Meeting, October 11-13, 2023, Klosters, Switzerland, external page Online

C. Nunes, A. Chernov, M. P. Garcia, A. Hierlemann and M. Schröter, "hiPSC-derived RETT syndrome electrophysiology and molecular phenotypic screening platform for the development of new therapies", 12th Basel Postdoc Network Meeting, October 11-13, 2023, Klosters, Switzerland.

C. Donner, J. Bartram, P. Hornauer, T. Kim, D. Roqueiro, A. Hierlemann, G. Obozinski, M. Schröter, "Ensemble learning and ground-truth validation of synaptic connectivity inferred from spike trains", Society for Neuroscience Annual Conference, SfN 2023, November 11-15, 2023, Washington, USA, Poster 577.08/XX34. external page Online

Invited: A. Hierlemann, "Microphysiological systems and highly integrated microelectrode arrays", Oliver Brand Memorial Lectureship on Electronics and Nanotechnology, November 13, 2023, Georgia Institute of Technology, Atlanta, USA. external page Online

A. Bucci, M. Buettner, N. Domdei, F.B. Rosselli, R. Diggelmann, M. Znidaric, B. Roska, A. Hierlemann, W.M. Harmening, F. Franke, "Retinal ganglion cells in the human retina synchronize action potential arrival times at the optic disc", Society for Neuroscience Annual Conference, SfN 2023, November 11-15, 2023, Washington, USA, Poster 146.26/Z1. external page Online

K. Kasuba, A. Buccino, J. Bartram, B. Gaub, S. Kumar, S. Ronchi, S. Geissler, A. Hierlemann, D.J. Mueller, "Neurons differentiate magnitude, location and loading rate of mechanical forces", Society for Neuroscience Annual Conference, SfN 2023, November 11-15, 2023, Washington, USA, Poster 309.11 / XX16. external page Online

M. Murdeu, A. Hierlemann, J. Boos, T. Buerki-Thurnherr, "Human based placenta-embryo chip for developmental toxicity assessment of nanoparticles", EMPA PhD Symposium, November 28, 2023, Dübendorf, Switzerland, external page Online

Invited: A. Hierlemann, "CMOS-microelectronics-based extracellular electrophysiology at subcellular resolution", BioCube workshop: bioelectronics, -photonics, -mechanics, December 10-16, 2023, Sestriere, Italy, external page Online

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2022

A. Bucci, R. Diggelmann, M. Znidaric, M. De Gennaro, C. Cowan, B. Roska, A. Hierlemann, F. Franke, "Propagation speeds of action potentials in the human retina compensate for traveling distances", Swiss Eye Research Meeting, January 20-21, 2022, Morat/Murten, Switzerland, Booklet of abstracts, p 12. external page Online

A. Kurmashev, J. A. Boos, M. Modena, A. Hierlemann, "Microfluidic platform for continuous perfusion of transwell-based barrier models", AMR Conference, April 7-8, 2022, Basel, Switzerland. external page Online

M. Schröter, C. Wang, M. Terrigno, P. Hornauer, Z. Huang, R. Jagasia, A. Hierlemann, "Functional imaging of human brain organoids using high-density microelectrode arrays", BACEL3D, May 12-13, 2022, Basel, Switzerland, contribution #A-142. external page Online

A. Bucci, R. Diggelmann, M. Znidaric, M. De Gennaro, C. Cowan, B. Roska, A. Hierlemann, F. Franke, "Propagation speeds of action potentials in the human retina compensate for traveling distances", Vision Sciences Annual Meeting, May 13-18, 2022, St. Pete Beach, Florida, USA. external page Online

X. Xue, A. Buccino, S. Kumar, A. Hierlemann, J. Bartram, "Paired spine Ca²⁺ imaging and large-scale extracellular HD-MEA recordings for the identification of monosynaptic connections", Dendrites: Dendritic anatomy, molecules and function, May 23-26, 2022, Heraklion, Greece, Booklet of Abstracts, p. 32. external page Online

P. Hornauer, G. Prack, N. Anastasi, S. Ronchi, T. Kim, C. Donner, M. Fiscella, K. Borgwardt, V. Taylor, R. Jagasia, D. Roqueiro, A. Hierlemann, M. Schröter "Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation", Personalized Health Technologies, June 7-8, 2022, Zurich, Switzerland. external page Online

A. Kurmashev, J. A. Boos, M. Modena, A. Hierlemann, "Microfluidic platform for continuous perfusion of transwell-based barrier models", EMBL-IBEC Winter Conference 2022, June 8-10, 2022, Barcelona, Spain, Booklet of Abstracts, p. 122-123. external page Online

C. Lohasz, D. Hasanova, S. Lützow, L. Hölting, M. Rudnik, A. Hierlemann, O. Frey, M. Modena, "hiFlow: a human immune flow platform for evaluation of cancer immunotherapy approaches", European Organ-on-Chip Society (EUROoCS) International Conference, July 4-5, 2022, Grenoble, France. external page Online

O. T. P. Nguyen, C. Lohasz, P. M. Misun, J. Lee, A. Hierlemann, "Immunocompetent Microphysiological System: Anti-tumor Activity and Toxicity by Natural Killer Cells", European Organ-on-Chip Society (EUROoCS) International Conference, July 4-5, 2022, Grenoble, France. external page Online

J. B. Petr, L. Vivancos Stalin, M. Baumgartner, A. Hierlemann, M. M. Modena, "Microfluidic Platform for Continous, High-Resolution Imaging of Organotypic Brain-Tissue Slices", European Organ-on-Chip Society (EUROoCS) International Conference, July 4-5, 2022, Grenoble, France. external page Online

J. Lee, T. Gänswein, H. Ulusan, V. Emmenegger, A. M. Saguner, F. Duru, A. Hierlemann, "Repeated and on-demand intracellular recording of cardiomyocytes", 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts, p. 13-14. external page Online

R. Bounik, F. Cardes, V. Viswam, M. M. Modena, A. Hierlemann, "A new CMOS-electrode-array-based impedance sensor integrated into an open microfluidic platform", 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts p. 124-125. external page Online  

T. Gänswein. S. S. Kumar, A. Buccino, X. Xue, J. Bartram, V. Emmenegger, A. Hierlemann, "Tracking axon-initial-segment plasticity using high-density microelectrode arrays: A computational study", 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts, p. 126-127. external page Online

H. Ulusan, R. Diggelmann, C. Magnan, M. Znidaric, V. Viswam, F. Franke, and A. Hierlemann, “Impedance Measurements and Electrophysiological Recordings of Mouse Retinae on a Multifunctional HD-MEA Platform”, 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts p. 175-176. external page Online

C. Magnan, H. Ulusan, R. Diggelmann, and A. Hierlemann "Electrochemical Measurement Platform within Multi-functional High-density Microelectrode Array”, 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts p. 122-123. external page Online

P. Hornauer, G. Prack, N. Anastasi, S. Ronchi, T. Kim, C. Donner, M. Fiscella, K. Borgwardt, V. Taylor, R. Jagasia, D. Roqueiro, A. Hierlemann, M. Schröter "DeePhys, a machine learning-driven platform for electrophysiological phenotype screening of human stem-cell derived neuronal networks", 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts p. 158-160. external page Online

X. Xue, A. Buccino, S. Kumar, A. Hierlemann, J. Bartram, "High-throughput ground-truth validation of neuronal spike sorting algorithms", 12th International Conference on Microelectrode Arrays for Life Sciences (MEA Meeting), July 06-08, 2022, Tübingen, Germany, Booklet of Abstracts, p. 128-129. external page Online

X. Xue, A. Buccino, S. Kumar, A. Hierlemann, J. Bartram, "A novel multimodal approach for probing synaptic connectivity and properties", FENS Forum, July 11-13, 2022, Paris, France, Booklet of Abstracts, p. 3200. external page Online

W. Wei, A. Hierlemann, M. M. Modena, "3D in vitro Blood-Brain-Barrier Model with Integrated TEER  Sensor for Investigating the Pathogenesis of Cerebral Ischemia",  Microfluidics EMBL Conference, July 11-13, 2022, Heidelberg, Germany, Booklet of Abstracts, p.74. external page Online

Invited: A. Hierlemann: "Microphysiological systems featuring microfluidic and microsensor structures", Microfluidics EMBL Conference, July 11-13, 2022, Heidelberg, Germany, Booklet of Abstracts, p.74. external page Online

P. Hornauer, G. Prack, N. Anastasi, S. Ronchi, T. Kim, C. Donner, M. Fiscella, K. Borgwardt, V. Taylor, R. Jagasia, D. Roqueiro, A. Hierlemann, M. Schröter "DeePhys, a machine learning-driven platform for electrophysiological phenotype screening of human stem-cell derived neuronal networks", ISSCR Madison International Symposium, September 21-23, 2022, Madison, Wisconsin, USA. external page Online

R. Bounik, J. Lee, V. Viswam , F. Cardes, M. M. Modena, A. Hierlemann, "A CMOS Microelectrode Array Integrated into an Open, Continuously Perfused Microfluidic System", Proceedings IEEE Biomedical Circuits and Systems Conference (BioCAS), October 13-15, 2022, Taipei, Taiwan, Proceedings p. 491-494. external page Online

P. Hornauer, G. Prack, N. Anastasi, S. Ronchi, T. Kim, C. Donner, M. Fiscella, K. Borgwardt, V. Taylor, R. Jagasia, D. Roqueiro, A. Hierlemann, M. Schröter "Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation", 51st Annual Meeting of the Society for Neuroscience, November 12–16, 2022, San Diego, California, USA, Poster 703.09 / F36. external page Online

M. Büttner. M. Znidaric, R. Diggelmann, A. Bucci,  A. Hierlemann, F. Franke, "Revealing nonlinear computations in the retina using random motion stimuli", 51st Annual Meeting of the Society for Neuroscience 2022, November 12–16, San Diego, California, USA, Poster 296.09 / U3 . external page Online

T. Gänswein. S. S. Kumar, A. Buccino, V. Emmenegger, A. Hierlemann, "Exploring the feasibility of tracking axon initial segment plasticity by means of high-resolution extracellular electrophysiology", 51st Annual Meeting of the Society for Neuroscience 2022, November 12–16, San Diego, California, USA, Poster 088.17 / XX19. external page Online

C. Sampaio da Silva, R. Limacher, C. Beyer, F. Gökçe, T. Valentin, A. Hierlemann and V. Revol, "Electrical impedance spectroscopy platform for label-free characterization of microtissues with facing electrodes", NanoBioTech Conference, November 14-16, 2022, Montreux, Switzerland. external page Online

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2021

J. B. Petr, L. Vivancos, M. Baumgartner, A. Hierlemann, M. Modena, "Microfluidic Platform for Continuous, High-Resolution Imaging of Ex Vivo Tissue Slices", Agora Workshop «Organoids in Cancer Research», November 24, 2021, Lausanne, Switzerland.  external page Online

Invited Keynote: A. Hierlemann, "Microtechnology and microelectronics to characterize neurons and networks at subcellular resolution", NanoBioTech Conference, November 15-17, 2021, Montreux, Switzerland. external page Online

O. T. P. Nguyen, P. M. Misun, C. Lohasz, J. Lee, A. Hierlemann, "Immunocompetent microphysiological system for simultaneous efficacy and safety assessment of immune-cell-based anti-cancer therapies", Proceedings 25^th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 10-14, 2021, Virtual Conference. external page Online

N. Rousset, R. López Sandoval, M. M. Modena, A. Hierlemann, P. M. Misun, "Modeling and measuring glucose consumption by cancer spheroids in hanging drops using integrated biosensors", Proceedings 25^th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 10-14, 2021, Virtual Conference. external page Online

W. Wei, A. Hierlemann, M. Modena, "Hanging-drop-based, 3D blood-brain-barrier model", Proceedings 25^th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 10-14, 2021, Virtual Conference. external page Online

J. A. Boos, P. M. Misun, G. Brunoldi, L. A. Furer, L. Aengenheister, M. Modena, N. Rousset, T. Bürki-Thurnherr, A. Hierlemann, "Microfluidic multi-tissue platform for systemic embryotoxicity testing along the maternal-placental-embryonic axis", Proceedings 25^th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 10-14, 2021, Virtual Conference. external page Online

A. Kurmashev, J. A. Boos, M. Modena, A. Hierlemann, "Microfluidic platform for continuous perfusion of transwell-based barrier models", Proceedings 25^th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 10-14, 2021, Virtual Conference. external page Online

P.S. Shabestari, A P. Buccino, S.S. Kumar, A. Pedrocchi, A. Hierlemann, "A modulated template-matching approach to improve spike sorting of bursting neurons", Proceedings IEEE Biomedical Circuits and Systems Conference (BioCAS), October 6-9, 2021, Virtual Conference, Paper 7023 (DOI: 10.1109/BioCAS49922.2021.9644995). external page Online

J. Lee, A. Hohn, V. Emmenegger, H. Ulusan, I. Akin, A. M. Saguner, X. Zhou, F. Duru, A. Hierlemann, I. El-Battrawy, "Functional characterization of drug responses in induced pluripotent stem cell-derived cardiomyocytes from a short QT syndrome type 5 patient", European Heart Rhythm Association (EHRA) Congress 2021, April 23-25, 2021, Virtual Conference, Proceedings EP Europace, Volume 23, Issue Supplement 3, euab116.546, (DOI: 10.1093/europace/euab116.546). external page Online

Invited: A. Hierlemann, "CMOS microelectronic systems to characterize neurons and networks at subcellular resolution", Materials Research Society Virtual Spring Meeting, April 17-23, 2021. external page Online

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2020

Invited Keynote: A. Hierlemann, "Extracellular electrophysiological characterization of neurons and networks at subcellular resolution", 9th Basic and Clinical Neuroscience Congress, December 9-11, 2020, Tehran, Iran. external page Online

A. Buccino, T. Damart, D. Mandge, M. Zbili, W. Van Geit, H. Markram and A. Hierlemann, "A multi-modal fitting procedure to construct biophysically detailed multicompartment neuronal models", Neuromatch 3.0, October 26-30, 2020, Virtual Conference. external page Online

F. Gökçe, M.M. Modena, B. Bornhauser and A. Hierlemann, "Microphysiological drug-screening platform for personalized leukemia treatment", 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), October 4-9, 2020, Virtual Conference. external page Online

T. Kim, P. Hornauer, C. Donner, A. Hierlemann, K. Borgwardt, M. Schröter and D. Roqueiro.  "Comparison of connectivity inference algorithms for classification of neuronal cultures using graph kernels", ECML PKDD Workshop on Machine Learning for Pharma and Healthcare Applications, PharmML, September 14, 2020, Virtual Workshop, external page Online

O.T.P. Nguyen, P. Vonschallen, A. Hierlemann and P.M. Misun, "A versatile gut-on-chip platform for studying intestinal crosstalk", European Organ-on-Chip Society (EUROoCS) International Conference, July 8-9, 2020, Virtual Conference. external page Online

W. Wei, M.M. Modena and A. Hierlemann, "A 3D in vitro blood-brain-barrier model for investigating the pathogenesis of CNS diseases and the transport of drugs", European Organ-on-Chip Society (EUROoCS) International Conference, July 8-9, 2020, Virtual Conference.  external page Online

J. Boos, G. Brunoldi, P. Misun, T. Bürki-Thurnherr and A. Hierlemann, "Placenta on a chip: integrating a placenta model into the metaEST platform", European Organ-on-Chip Society (EUROoCS) International Conference, July 8-9, 2020, Virtual Conference.  external page Online

F. Gökçe, B. Servais, M.M. Modena and A. Hierlemann, "Studying interactions between human liver and bone marrow microtissues for personalized leukemia treatments", European Organ-on-Chip Society (EUROoCS) International Conference, July 8-9, 2020, Virtual Conference. external page Online

N. Rousset, A. Hierlemann, P. Misun, "Investigating 3D microtissue metabolism using hanging drops with integrated biosensors", European Organ-on-Chip Society (EUROoCS) International Conference, July 8-9, 2020, Virtual Conference. external page Online

F. Gökçe, M.M. Modena and A. Hierlemann, "Physiologically relevant drug-screening approaches to personalize leukemia treatments", Personalized Health Technologies, June 29-30, 2020, Zurich, Switzerland. external page Online

S. Ronchi, G. Prack, M. Fiscella and A. Hierlemann, "Functional characterization of human iPSC-derived neuronal networks using high-density microelectrode arrays", International Society for Stem Cell Research Conference (ISSCR), June 23-27, 2020, Virtual Conference. external page Online

P. Hornauer, G. Prack, C. Donner, D. Roqueiro, V. Taylor, K. Borgwardt, A. Hierlemann and M. Schröter, "Electrophysiological characterization of α-synuclein function in human iPSC-derived dopaminergic neurons using high-density microelectrode arrays", International Society for Stem Cell Research Conference (ISSCR), June 23-27, 2020, Virtual Conference. external page Online

M. Fiscella, S. Ronchi, G. Prack and A. Hierlemann, "Functional characterization of axons in human iPSC-derived neurons modeling brain diseases by high-density microelectrode arrays", International Society for Stem Cell Research Conference (ISSCR), June 23-27, 2020, Virtual Conference. external page Online

K. C. Kasuba, B. M. Gaub, S. Ronchi, D. J. Mueller, A. Hierlemann, "Neuromechanics of mammalian cortical neurons", Biophysical Journal 2020, 118 (3), 602a (DOI: https://doi.org/10.1016/j.bpj.2019.11.3253). external page Online  

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2019

Invited: A. Hierlemann, "Extracellular electrophysiological characterization of neurons and networks at subcellular resolution", EMBO Workshop on Precision Health: Molecular Basis, Technology and Digital Health, November 13-16, 2019, Heidelberg, Germany. external page Online

G. Zorzi, M. Fiscella, S. Ronchi, G. Prack, A. Hierlemann, "Electrophysiological phenotype characterization of multiple human iPSC-derived neuron lines by means of high-resolution microelectrode arrays",  International Society for Stem Cell Research (ISSCR) International Symposium, November 6-8, 2019, Toronto, Canada. external page Online

C. Lohasz, F. Bonanini, K. Renggli, O. Frey, A. Hierlemann, "A liver-tumor co-culture system to assess metabolism-related drug-drug interactions", Proceedings 23^rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 27-31, 2019, Basel, Switzerland.  external page Online

O. T. P. Nguyen, P. M. Misun, C. Lohasz, R. Nudischer, O. Frey, J. Devan, G. De Libero, A. Hierlemann and K. Renggli, "Investigating the intercellular interaction between 3D gut epithelial microtissues and circulating MAIT cells using a microfluidic tilting platform", Proceedings 23^rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 27-31, 2019, Basel, Switzerland.  external page Online

L. Dong, M. M. Modena, A. Hierlemann, "Passive wireless sensing of microtissue properties", Proceedings 23^rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 27-31, 2019, Basel, Switzerland.  external page Online

F. Gökçe, A. Hierlemann and M. M. Modena, "Tubing-free microfluidic platform for co-culture of 2D adherent cells and 3D microtissue spheroids", Proceedings 23^rd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 27-31, 2019, Basel, Switzerland.  external page Online

T. Kim, J. Bartram, A. Hierlemann, M. Schröter, "Connectivity profiling and single-cell RNA sequencing to study homeostatic plasticity in hippocampal neuronal networks in vitro". Society for Neuroscience (SfN) Meeting, October 19-23, 2019, Chicago, Illinois, USA, Contribution 548.05. external page Online

R. Diggelmann, M. Znidaric, A. Bucci, A. Hierlemann, and F. Franke, "Improved receptive-field characterization of retinal ganglion cells using a large field-of-view light stimuli", Society for Neuroscience (SfN) Meeting, October 19-23, 2019, Chicago, Illinois, USA, Contribution 225.27. external page Online

A. Bucci, R. Diggelmann, M. Znidaric, B. Roska, R. Da Silveira, A. Hierlemann, F. Franke,  "How the coupling strength of horizontal cells effects the retinal processing of spatio-temporal light stimuli - Model and experiments", Society for Neuroscience (SfN) Meeting, October 19-23, 2019, Chicago, Illinois, USA, Contribution 225.28. external page Online

M. Znidaric, R. Diggelmann, A. Bucci, A. Hierlemann, F. Franke, "Ex vivo mouse retinal recordings using HD-MEA systems: From characterizing single cells to analyzing populations", Society for Neuroscience (SfN) Meeting, October 19-23, 2019, Chicago, Illinois, USA, Contribution 225.29. external page Online

X. Xue, T. Lummen, A. Hierlemann and J. Bartram, "Investigating dendritic signals evoked by natural patterns of presynaptic activity", Society for Neuroscience (SfN) Meeting, October 19-23, 2019, Chicago, Illinois, USA, Contribution 737.18.  external page Online

Invited: A. Hierlemann, "Subcellular-resolution extracellular electrophysiology with CMOS-based high-density microelectrode arrays", STIM-REI Research Workshop on Interdisciplinary endeavor in technology at nanoscale, water and environment, October 9-11, 2019, Split, Croatia. external page Online

Invited: A. Hierlemann, "Extracellular electrophysiological characterization of neurons and networks at subcellular resolution", Asilomar Bioelectronics Symposium, September 3-7, 2019, Asilomar, Monterey, USA. external page Online

C. Lohasz, K. Renggli, F. Bonanini, O. Frey, A. Hierlemann, "Generation of physiological flow conditions for arrays of microtissues through gravity-driven flow", 1^st Annual conference of the European Organ-on-Chip Society (EUROoC), July 2-3, 2019, Graz, Austria. external page Online

P. M. Misun, J.A. Boos, N. Rousset, O. Frey, A. Hierlemann, "Microfluidic hanging-drop platforms for culture, interaction and analysis of 3D microtissues", 1^st Annual conference of the European Organ-on-Chip Society (EUROoC), July 2-3, 2019, Graz, Austria. external page Online

O. T. P. Nguyen, A. Hierlemann and K. Renggli, "A modular microfluidic platform with gravity-driven flow for establishing intestinal barrier models", 1^st Annual conference of the European Organ-on-Chip Society (EUROoC), July 2-3, 2019, Graz, Austria. external page Online

M. Fiscella, G. Zorzi, S. Ronchi, G. Prack, M. Schröter, A. Hierlemann, "Electrophysiological phenotype characterization of human iPSC-derived neuronal-cell lines by means of high-resolution microelectrode arrays”, ISSCR Annual Meeting, June 26th - 29^th, 2019 Los Angeles, USA. external page Online

M. Schröter, D. Roqueiro, G. Prack, M. Fiscella, K. Borgwardt, A. Hierlemann, “Machine learning for deep electrophysiological phenotyping of human dopaminergic neurons", ISSCR Annual Meeting, June 26th - 29^th, 2019 Los Angeles, USA. external page Online

Invited: A. Hierlemann, "Subcellular-resolution electrophysiology with highly Integrated CMOS-based microelectrode arrays", 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, July 23-27, 2019, Berlin, Germany. external page Online

F. Gökçe, P. S. Ravaynia, A. J. Kaestli, M. M. Modena, A. Hierlemann and K. Renggli, "Leukemia on chip – Electrical impedance spectroscopy as an online readout to investigate drug-cancer interaction", Proceedings 20^th International Conference on Solid-State Sensors, Actuators and Microsystems & Eurosensors XXXIII (Transducers & Eurosensors XXXIII), June 23-27, 2019, Berlin, Germany, pp. 606-608. (DOI: 10.1109/TRANSDUCERS.2019.8808781). external page Online

N. Rousset, P.M. Misun, A. Hierlemann, "Measuring and simulating glucose and lactate metabolism by cancer spheroids in microfluidic hanging drops", Tumor Metabolism (B5), February 24-28, 2019, Keystone, Colorado, USA. external page Online

F. Gökçe, A. J. Kaestli, P. S. Ravaynia, M. de Geus, M. M. Modena, A. Hierlemann and K. Renggli, "Leukemia on chip – A drug-screening platform for real-time monitoring of patient-derived acute lymphoblastic leukemia", Proceedings 6th International Winterschool on Bioelectronics (BioEl 2019), March 15-23, 2019, Kirchberg, Tirol, Austria. external page Online

R. Bounik, M. Gusmaroli, P. M. Misun , V. Viswam, A. Hierlemann, M. M. Modena, “Integration of discrete sensors and microelectrode arrays into open microfluidic hanging-drop networks”, Proceedings IEEE International Conference on Micro Electro Mechanical Systems (MEMS), January 27-31, 2019, Seoul, Korea (South), pp. 441-444, (DOI: 10.1109/MEMSYS.2019.8870732). external page Online

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2018

K. Renggli, A. Hierlemann, "Organs on a chip - Challenges and perspectives for future applications", OpenTox Association Workshop, December 19, 2018, Basel, Switzerland.

R. Nudischer, C. Bertinetti-Lapatki, K. Renggli, C. Claus, A.B. Roth, "Establishment and characterization of three-dimensional mouse liver spheroids for mechanistic studies in cancer immunotherapy", Roche 3rd Pharmaceutical Science Organs-on-a-Chip Symposium, December 14, 2018, Basel, Switzerland.

Invited: A. Hierlemann, "Direct interfacing of neurons with CMOS microelectronics", IEEE EMBS Micro and Nanotechnology in Medicine Conference, December 10-14, 2018, Kauai, Hawaii, USA. external page Online

J. Boos, M. Modena, P. M. Misun, K. Renggli, O. Frey, A. Hierlemann, "Microfluidic multi-organ platform to study the effect of prodrugs on early embryonic development", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), November 11-15, 2018, Koahsiung, Taiwan. external page Online

P. Ravaynia, K. Chawla, M. Modena, F. Lombardo, J. Keiser, A. Hierlemann, "Microfluidic impedance platform for long-term detection of parasite viability", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), November 11-15, 2018, Koahsiung, Taiwan. external page Online

N. Rousset, P. M. Misun, A. Hierlemann, "Predicting and measuring glucose and lactate metabolism of cancer spheroids in hanging-drop networks", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), November 11-15, 2018, Koahsiung, Taiwan. external page Online

C. Lohasz, P. Argast, M. Rausch, M. Wartmann, J. Loretan, E. Goerlach, O. Frey, K. Renggli, A. Hierlemann, "Microphysiological platform for live 3D high-resolution imaging of multiple interconnected and interacting microtissues", Proceedings of the 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), November 11-15, 2018, Koahsiung, Taiwan. external page Online

A.J. Kaestli, M. de Geus, B. Mouttet, C. Lohasz, N. Rousset, F. Bonanini, F. Gökce, Y. Huang, B. Bornhauser, J.-P. Bourquin, A. Hierlemann, K. Renggli, "Microtissues Meet Microfluidics – Leukemia on Chip”, International Organ-on-Chip Symposium, November 8-9, 2018, Eindhoven, The Netherlands. external page Online

J. Bartram, M. Schröter, S. Ronchi, V. Emmenegger, J. Müller, A. Hierlemann, "Mechanisms of homeostatic synaptic plasticity", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA. Contribution 037.11. external page Online

M. Girr, J. Boos, P. Misun, J. Bartram, M. Renner, M. Gazorpak, A. Hierlemann, M. Schröter, "Spontaneous neuronal activity in developing mouse cerebral organoids", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA. Contribution 724.14. external page Online

S. Ronchi, M. Fiscella, C. Marchetti, V. Viswam, J. Müller, U. Frey, A. Hierlemann, "Single-neuron sub-cellular-resolution electrical stimulation with high-density microelectrode arrays", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA. Contribution 174.05. external page Online

A. Drinnenberg, F. Franke, R. Morikawa, J. Jüttner, A. Hierlemann, R. da Silveira, B. Roska, "How feedback at the first visual synapse shapes functional diversity in the retina", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA, Contribution 395.04. external page Online

M. Lewandowska, E. Bogatikov, A. Hierlemann, A. Punga, "Long-term high-density extracellular recordings enable studies of muscle cell physiology and pathology", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA, Contribution 700.13. external page Online

M. Fiscella, N. Leary, S. Ronchi and A. Hierlemann, "Electrophysiological phenotype characterization of human iPSC-derived dopaminergic neuronal lines by means of high-resolution microelectrode array", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA, Contribution 700.13. external page Online

V. Emmenegger, J. Bartram, S. Sitnikov, A. Hierlemann, "Investigating the analog modulation of action-potential waveforms in axonal arbors of cortical neurons using whole-cell patch-clamp recordings and high-density microelectrode arrays", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA, Contribution 203.05. external page Online

S. Idrees, M.-P. Baumann, F. Franke, Z. Hafed, T. Münch, "Extra-retinal mechanisms as compensation for retinal-circuit-level visual suppression around saccades", Society for Neuroscience (SfN) Meeting, November 3-7, 2018, San Diego, CA, USA, Contribution 061.06. external page Online

X. Yuan, V. Emmenegger, M. J. Obien, A. Hierlemann, U. Frey, "Dual-Mode Microelectrode Array Featuring 20k Electrodes and High SNR for Extracellular Recording of Neural Networks", Proceedings IEEE Biomedical Circuits and Systems Conference (BioCAS), October 17-19, 2018, Cleveland, Ohio, USA, paper 6065 (DOI: 10.1109/BIOCAS.2018.8584735). external page Online

Invited: A. Hierlemann, "Microphysiological systems featuring microfluidic and microsensor structures", Tagungsband 19. Heiligenstädter Kolloquium, September 24-26, 2018, Heiligenstadt, Germany, pp. 251-254 (ISBN 978-3-00-060656-4). external page Online

Invited: A. Hierlemann, "Versatile microphysiological systems including microfluidic and microsensor structures", Microsystems and Nanoengineering Summit, MINE, July 9-11, 2018, Beijing, China. external page Online

Invited Keynote: A. Hierlemann, "Microfluidic and microsensor structures for "body-on-a-chip" systems", Workshop on Microfluidic Chip and Tissue Engineering, WMCTE, July 12-14, 2018, Nanjing, China, external page Online

A. Drinnenberg, F. Franke, R. Morikawa, J. Jüttner, A. Hierlemann, R. da Silveira, B. Roska. "Horizontal cell feedback differentially shapes the response dynamics of distinct retinal output channels", 14th Federation of American Societies for Experimental Biology (FASEB) Science and Research Conference on Retinal Neurobiology and Visual Processing, June 24-29, 2018, Olean, NY, USA. external page Online

F. Franke, A. Drinnenberg, R. Morikawa, J. Jüttner, A. Hierlemann, B. Roska, R. da Silveira. "How diverse retinal functions arise from feedback at the first visual synapse", 14th Federation of American Societies for Experimental Biology (FASEB) Science and Research Conference on Retinal Neurobiology and Visual Processing, June 24-29, 2018, Olean, NY, USA. external page Online

A. Drinnenberg, F. Franke, R. Morikawa, J. Jüttner, A. Hierlemann, R. da Silveira, B. Roska. "How diverse retinal functions arise at the first visual synapse", 11th FENS Forum of Neuroscience, July 7-11, 2018, Berlin, Germany. external page Online

F. Franke, A. Drinnenberg, R. Morikawa, J. Jüttner, A. Hierlemann, B. Roska, R. da Silveira. "How feedback inhibition at the first visual synapse shapes functional diversity in the retina", 11th FENS Forum of Neuroscience, July 7-11, 2018, Berlin, Germany. external page Online

A. Bucci, R. Diggelmann, A. Drinnenberg, M. Znidaric, B. Roska, R. da Silveira, A. Hierlemann, F. Franke, "The role of horizontal cells in spatial computation in early visual processing", 11th FENS Forum of Neuroscience, July 7-11, 2018, Berlin, Germany. external page Online

R. Diggelmann, A. Hierlemann, F. Franke, "Effective benchmarking of high-density MEA spike-sorters", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), July 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00092). external page Online

M. Znidaric, A. Bucci, R. Diggelmann, A. Hierlemann, F. Franke, "Large field-of-view HD-MEA setup for ex vivo mouse retina electrophysiological recordings", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00100). external page Online

J. Bartram, M. Schröter, S. Ronchi, V. Emmenegger, J. Müller and A. Hierlemann. "Probing synaptic connectivity and function using high-density microelectrode arrays and whole-cell patch-clamp recordings", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00085). external page Online

S. Ronchi, M. Fiscella, J. Müller, V. Viswam, U. Frey, A. Hierlemann, "Single-cell electrical stimulation with CMOS-based high-density microelectrode arrays",11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00086). external page Online

M. Schröter, M. Girr, J. Boos, M. Renner, M. Gazorpak, W. Gong, J. Bartram, J. Müller, A. Hierlemann, "Mapping neuronal network dynamics in developing cerebral organoids", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00066). external page Online

M. Engelene Obien, G. Zorzi, M. Fiscella, N. Leary and A. Hierlemann, "Comparison of axonal-conduction velocity in developing primary cells and human iPSC-derived neurons", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00095). external page Online

G. Zorzi, M. Engelene Obien, M. Fiscella, N. Leary and A. Hierlemann, "Automatic extraction of axonal arbor morphology applied to h-iPSC-derived neurons", MEA Meeting 2018, 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00049). external page Online

R. Bounik, M. Gusmaroli, V. Viswam, M. Modena and A. Hierlemann, "COMSOL modeling of an integrated impedance sensor in a hanging-drop platform", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI:10.3389/conf.fncel.2018.38.00083). external page Online

X. Yuan, A. Hierlemann, U. Frey, "Dual-mode Microelectrode Array with 20k-electrodes and High SNR for High-Throughput Extracellular Recording and Stimulation", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00088). external page Online

C. Urwyler, R. Bounik, V. Viswam and A. Hierlemann, "Electrical impedance tomography on high-density microelectrode arrays", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00084). external page Online

M. Fiscella, N. Leary, E. Acun, S. Ronchi and A. Hierlemann, "Electrophysiological phenotype characterization of human iPSC-derived dopaminergic neuronal lines by means of high-resolution microelelectrode arrays", 11th International Meeting on Substrate Integrated Microelectrode Arrays (MEA Meeting), Jul 4-6, 2018, Reutlingen, Germany, Front. Cell. Neurosci. Conference Abstract (DOI: 10.3389/conf.fncel.2018.38.00014). external page Online

M. Fiscella, N. Leary, E. Acun, S. Ronchi and A. Hierlemann, "Electrophysiological phenotype characterization of human iPSC-derived dopaminergic neuronal lines by means of high-resolution microelelectrode arrays", International Society for Stem Cell Research (ISSCR) Annual Meeting, June 20-23, 2018, Melbourne, Australia. external page Online

F. Hürlimann, C. Lohasz, B. Yeslidag, D. Fluri, K. Renggli, A. Hierlemann, O. Frey, "A microfluidic multi-tissue platform engineered for 3D InSight microtissues", 78th Scientific Sessions, American Diabetes Association, June 22-26, 2018, Orlando, Florida, USA. external page Online

C. Lohasz, O. Frey, K. Renggli, A. Hierlemann, "A tubing-free, microfluidic tilting platform for the realization of in vivo-like drug exposure scenarios for three-dimensional microtissues", Book of Abstracts Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 168. external page Online

F. Hürlimann, S. Mannino, C. Lohasz, K. Renggli, A. Hierlemann, L. Suter-Dick, O. Frey, "Microphysiological system based on human liver microtissues for intrinsic clearance prediction", Book of Abstracts Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 145. external page Online

R. Nudischer, C. Bertinetti-Lapatki, C. Claus, K. Renggli, C. Lohasz, O. Frey, A. Hierlemann, A. Roth, "Towards a three-dimensional microfluidic in vitro model to assess efficacy & safety of immune-stimulatory antibody drugs", Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 121. external page Online

J. Boos, A. Michlmayr, K. Renggli, O. Frey, A. Hierlemann, "Microfluidic platform for advanced embryotoxicity testing in vitro", Book of Abstracts Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 76. external page Online

N. Rousset, M. de Geus, A. Kaestli, K. Renggli, A. Hierlemann. "Towards controlling the mobility of flowing cells in a hanging-drop network for microphysiological systems", Book of Abstracts Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 142. external page Online

K. Renggli, C. Lohasz, S. Bürgel, D. Fluri, A. Hierlemann, O. Frey. "Microtissues meet microfluidics – next generation microphysiological tilting system", Book of Abstracts Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 59. external page Online

M. Modena, K. Chawla, F. Lombardo, S. Bürgel, G. Panic, J. Keiser, A. Hierlemann, "Impedance analysis of viability of Schistosoma mansoni larvae for drug screning applications", Book of Abstracts Dechema 3D Cell Culture, June 5-7, 2018, Freiburg, Germany, p. 185. external page Online

K. Chawla, M. Modena, P. Ravaynia, F. Lombardo, G. Panic, S. Bürgel, J. Keiser, A. Hierlemann, "Microfluidic platform for parallelized and automated viability detection of Schistosoma mansoni", SELECT Bio Lab-on-a-chip and microfluidics Europe conference, June 5-6, 2018, Rotterdam, Netherlands. external page Online

C. Lohasz, K. Renggli, O. Frey, A. Hierlemann. "A versatile microfluidic chip for interconnecting multiple organs", CBMS European Organ-on-Chip Conference, May 24-25, 2018, Stuttgart, Germany. external page Online

S. Idrees, F. Franke, Z. Hafed, T. Münch, "Extra-retinal mechanisms as compensation for retinal-circuit-level visual masking effects in saccadic suppression", Vision Sciences Society Annual Meeting, May 18 – 23, 2018, St. Pete Beach, Florida, USA (DOI: 10.1167/18.10.199). external page Online

A. Kaestli, M. de Geus, B. Mouttet, C. Lohasz, Y. Huang, B. Bornhauser, J-P. Bourquin, A. Hierlemann, K. Renggli. "Leukemia on chip – Flow- and metabolism-based microphysiological multi-tissue system for patient-derived liquid biopsies", Keystone Symposia on Molecular and Cellular Biology D1: Organs- and Tissues on Chips, April 8-12, 2018, Big Sky, Montana, USA. external page Online

R. Nudischer, C. Bertinetti-Lapatki, C. Claus, K. Renggli, C. Lohasz, O. Frey, A. Hierlemann, A. Roth. "Towards a Three-Dimensional Microfluidic in vitroModel to Assess Efficacy & Safety of Immune-Stimulatory Antibody Drugs", Keystone Symposia on Molecular and Cellular Biology D1: Organs- and Tissues on Chips, April 8-12, 2018, Big Sky, Montana, USA. external page Online

P. Misun, A. Ringauf, C. Lohasz, O. Frey, A. Hierlemann. "A microfluidic multi-tissue system to study the interaction of pancreatic islets and liver microtissues", Keystone Symposia on Molecular and Cellular Biology D1: Organs- and Tissues on Chips, April 8-12, 2018, Big Sky, Montana, USA. external page Online

F. Hürlimann, C. Lohasz, D. Asgeirsson, K. Renggli, B. Yesildag, D. Fluri, A. Hierlemann, O. Frey. "Automating Multi-Tissue Microphysiological Systems Based on 3D Microtissues", Keystone Symposia on Molecular and Cellular Biology D1: Organs- and Tissues on Chips, April 8-12, 2018, Big Sky, Montana, USA. external page Online

J. Boos, A. Michlmayr, K. Renggli, O. Frey, A. Hierlemann, "Multi-organ platform for systemic embryotoxicity testing in vitro", Keystone Symposia on Molecular and Cellular Biology D1: Organs- and Tissues on Chips, April 8-12, 2018, Big Sky, Montana, USA. external page Online

C. Lohasz, P. Misun, F. Bonanini, F. Hürlimann, O. Frey, K. Renggli, A. Hierlemann. "Microphysiological multi-tissue platform for simultaneous efficacy and toxicity testing of drug formulations", 255th American Chemical Society National Meeting, March 18-22, 2018, New Orleans, LA, USA. external page Online

B. Yesildag, P.M. Misun, F. Forschler, A. Neelakandhan, A. Biernath, A. Hierlemann, O. Frey, "Using Uniform Reaggregated Pancreatic Islets in a Microfluidic Perifusion System Enables Studying Insulin Release Dynamics at Single-Islet Level", Keystone Symposia on Molecular and Cellular Biology B3: Frontiers in Islet Biology and Diabetes, February 4-8, 2018, Keystone, Colorado, USA. external page Online

F. Hürlimann, C. Lohasz, K. Renggli, J-Y. Kim, D. Fluri, A. Hierlemann, O. Frey. "Automating multi-tissue microphysiological systems based on 3D microtissues", Society for Laboratory Automation and Screening (SLAS) International Conference & Exhibition, February 3-7, 2018, San Diego, CA, USA. external page Online

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2017

Invited: A. Hierlemann, "Highly Integrated CMOS Microsystems to Interface with Neurons at Subcellular Resolution", Material Research Society Fall Meeting, November 26 - December 1, 2017, Boston, MA, USA, BM08.02.01. external page Online.

Invited: R. Diggelmann, “Retina on a Chip – Measuring Functional Properties of Retinal Ganglion Cells Using CMOS Microelectrode Arrays”, Biomedical Engineering Seminar of the University of Melbourne, November 29, 2017, Melbourne, Australia

A.J. Kaestli, M. de Geus, B. Mouttet, C. Lohasz, Y. Huang, B. Bornhauser, J.-P. Bourquin, A. Hierlemann, K. Renggli, "A Flow and Metabolism-Based Drug Screening Platform for Liquid Patient Samples", Stanford-EMBL Personalized Health Conference, November 1-4, 2017 Stanford, CA, USA. external page Online

J.A. Boos, A. Michlmayr, A. Birchler, O. Frey, A. Hierlemann, "Adding Metabolism to the Embryonic Stem Cell Test", Proceedings of the 21^st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS),  October 22-26, 2017, Savannah, GA, USA, pp. 842-843, ISBN: 978-0-692-94183-6. external page Online

P.M. Misun, F. Forschler, B. Yesildag, O. Frey, A. Hierlemann, "A Microfluidic Hanging-drop Perfusion System to Study the Secretion Dynamics of Single Pancreatic iIslet Microtissues”, Proceedings of the 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 22-26, 2017, Savannah, GA, USA, pp. 814-815, ISBN: 978-0-692-94183-6. external page Online

C. Lohasz, O. Frey, K. Renggli, A. Hierlemann, "A Microfluidic Tilting Platform for in vivo-like Drug Exposure of Three-Dimensional Microtissues", Proceedings of the 21^st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 22-26, 2017, Savannah, GA, USA, pp. 1015–1016, ISBN: 978-0-692-94183-6. external page Online

K.Chawla, M. Leonhardt, M. M. Modena, F.Lombardo, S.C. Bürgel, A. Hierlemann, "Microfluidic Impedance Platform for Automated Schistosomal Motility Detection", Proceedings of the 21^st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 22-26, 2017, Savannah, GA, USA, pp. 1098-1099, ISBN: 978-0-692-94183-6. external page Online

N. Rousset, M. de Geus, A.J. Kaestli, K. Renggli, A. Hierlemann, "Modeling Hanging-drop Networks to Optimize the Mobility of Flowing Cells in a Physiological Environment", Proceedings of the 21^st International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 22-26, 2017, Savannah, GA, USA, pp. 1173–1174, ISBN: 978-0-692-94183-6. external page Online

V. Viswam, M. Obien, U. Frey, F. Franke, A. Hierlemann, "Acquisition of Bioelectrical Signals with Small Electrodes", Proceedings IEEE Biomedical Circuits and Systems Conference (BioCAS), October 19-21, 2017, Torino, Italy, Paper 7111 (DOI: 10.1109/BIOCAS.2017.8325216). external page Online

Mario M. Modena, Ketki Chawla, Flavio Lombardo, Sebastian C. Bürgel, Gordana Panic, Jennifer Keiser, Andreas Hierlemann, "Impedance-based detection of Schistosoma mansoni larvae viability for drug screening", Proceedings IEEE Biomedical Circuits and Systems Conference (BioCAS), October 19-21, 2017, Torino, Italy, Paper 7041 (DOI: 10.1109/BIOCAS.2017.8325227). external page Online

K. Renggli, A. Hierlemann, O. Frey, "Adding Metabolic Competence to 3D Cell-Based Assays Using a Microtissue-based Microphysiological System", Open Meeting 2017 – Drug Metabolism Discussion Group, September 20-22, 2017, Cambridge, UK.

C. Lohasz, O. Frey, K. Renggli, A. Hierlemann. "A Tubing-Free, Microfluidic Platform for the Realization of Physiologically Relevant Dosing Curves on Cellular Models", Proceedings of Eurosensors 2017, MDPI Proceedings, 2017, Vol. 1, No. 4, p. 497-501 (DOI: 10.3390/proceedings1040497). external page Online

L. He, C. Lohasz, K. Renggli, D.A. Fluri, A. Hierlemann, O. Frey, "GravityFLOW: A Microtissue-Based Multi-Tissue Platform", World Congress – Alternatives and Animal Use in the Life Sciences, August 20-24, 2017, Seattle, WA, USA. external page Online

M. E. J. Obien, G. Zorzi, A. Hierlemann, “Mapping neuron cluster development based on axonal action potential propagation”, The 40th Annual Meeting of the Japan Neuroscience Society, July 20-23, 2017, Chiba, Japan

R. Diggelmann, M. Fiscella, A. Hierlemann, F. Franke, "Pre-whitening as a means to improve dimensionality reduction and simplify clustering in spike-sorters for multi-electrode recordings”, 26th Annual Computational Neuroscience Meeting (CNS2017), July 15-20, 2017, Antwerp, Belgium  external page Online

K. Renggli, P.M. Misun, E.A. Aeby, O. Frey, A. Hierlemann, "Hanging Drop Networks – Multi-Tissue Interaction and High-Resolution Microscopy of 3D Microtissues", SELECTBIO Organs-on-Chips World Congress and 3D-Cultures, July 10-11, 2017, Boston, MA, USA. external page Online

R. Nudischer, C. Bertinetti, O. Frey, K. Renggli, C. Lohasz, A. Hierlemann. A.B. Roth, "Towards a Three-Dimensional Microfluidic in vitro Model to Assess Efficacy & Safety in Cancer Immunotherapy", SELECTBIO Organs-on-Chips World Congress and 3D-Cultures, July 10-11, 2017, Boston, MA, USA. external page Online

C. Lohasz, O. Frey, K. Renggli, A. Hierlemann, "A Microfluidic Tilting Platform for Physiologically Relevant Drug Exposure of Three-Dimensional Microtissues", SELECTBIO Organs-on-Chips World Congress and 3D-Cultures, July 10-11, 2017, Boston, MA, USA. external page Online

V. Viswam, R. Bounik, A. Shadmani, J. Dragas, M. Obien, J. Müller, Y. Chen, A. Hierlemann, "High-density Mapping of Brain Slices Using a Large Multi-functional High-density CMOS Microelectrode Array System", Proceedings of the 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), Kaohsiung, Taiwan, June 18-22, 2017, pp. 135-138 (DOI: 10.1109/TRANSDUCERS.2017.7994006). external page Online

E. Aeby, P. Misun, M. Müller, K. Renggli, A. Hierlemann, O. Frey, "Microfluidic Hydrogel Hanging-drop Network for High-resolution Microscopy of 3D Microtissues", Proceedings of the 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), Kaohsiung, Taiwan, June 18-22, 2017, pp. 269-272 (DOI: 10.1109/TRANSDUCERS.2017.7994040). external page Online

Z. Zhu, P. Chen, R. Peng, K. Zheng, Y. Fan, A. Hierlemann, Q-A. Huang, "A Microfluidic 16×6-cell-trap Array for Comparative Cell Culturing", Proceedings of the 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), Kaohsiung, Taiwan, June 18-22, 2017, pp. 1781-1784 (DOI: 10.1109/TRANSDUCERS.2017.7994414). external page Online

M. Obien, J. Müller, J. Boos, R. Bounik, M. Fiscella,  and A. Hierlemann, "High-resolution Functional Imaging of Cardiomyocytes Derived from Embryonic Stem Cell Spheroids", International Society for Stem Cell Research (ISSCR) Meeting, June 14-17, 2017, Boston, MA, USA, T-3084. external page Online

M. Fiscella, J. Müller and A. Hierlemann, "High-resolution Microelectrode Array Platform for Biomarker Discovery and Novel Functional Assays in Human iPSC-derived Neurons", International Society for Stem Cell Research (ISSCR) Meeting, June 14-17, 2017, Boston, MA, USA, W-3027. external page Online

B. Yesildag, P.M. Misun, F. Forschler, A. Neelakandhan, A. Biernath, A. Hierleman, O. Frey, "Using Uniform Reaggregated Pancreatic Islets in a Microfluidic Perifusion System Enables Studying Insulin Release Dynamics at Single-islet Level", American Diabetes Association (ADA) 77^th Scientific Sessions,  June 9-13, 2017, San Diego, CA, USA. external page Online

Invited: U. Frey, M. Obien, J. Müller, and A. Hierlemann, "Technology Trends and Commercialization of High-density Microelectrode Arrays for Advanced In-vitro Electrophysiology", Proceedings of the IEEE International Symposium on Circuits and Systems (ISCAS), May 28-31, 2017, Baltimore, MD, USA, p. 10 (DOI: 10.1109/ISCAS.2017.8050215). external page Online

Invited: A. Hierlemann, "CMOS-based Monolithic Microelectrode Systems for Subcellular-resolution Electrophysiology and Sensor Applications", 3^rd International Workshop on Functionalized Surfaces for Sensor Applications, SURFOCAP, May 30-31, 2017, Besançon, France. external page Online

J.A. Boos, A. Michlmayr, A. Birchler, O. Frey, A. Hierlemann, "Adding Metabolism to the Embryonic Stem Cell Test", 2^ndInternational Organ-on-Chip Symposium, May 2-3, 2017, Lausanne, Switzerland. external page Online

J.A. Boos, P.M. Misun, O. Frey, K. Renggli, A. Hierlemann, "Microfluidic Hanging-Drop Networks for Physiological Multi-tissue Interaction and Analysis", 2^ndInternational Organ-on-Chip Symposium, May 2-3, 2017, Lausanne, Switzerland. external page Online

K. Renggli, C. Lohasz, J.-Y. Kim, D.A. Fluri, J.M. Kelm, O. Frey, A. Hierlemann, "Pro-Drug Activation in a Versatile Microtissue-Based Microfluidic Tilting Platform", 2^ndInternational Organ-on-Chip Symposium, May 2-3, 2017, Lausanne, Switzerland. external page Online

R. Nudischer, C. Bertinetti, A.B. Roth, C. Claus, C. Lohasz, O. Frey, K. Renggli, A. Hierlemann, "Mimicking Immune-Stimulatory Drugs in vitro Using Micro-Physiological Systems", Roche Global Safety Meeting, April 19, 2017, Basel, Switzerland.

P. Misun, A. Shadmani, A. Hierlemann, O. Frey, "Integrating Multi-electrode Arrays in Microfluidic Hanging-drop Networks" Proceedings of the 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), January 22-26, 2017, Las Vegas, NV, USA, pp. 91-94 (DOI: 10.1109/MEMSYS.2017.7863347). external page Online

Invited Plenary: A. Hierlemann, "Direct Interfacing of Neurons to Highly Integrated Microsystems", Proceedings of the 30th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), January 22-26, 2017, Las Vegas, NV, USA, pp. 199-204 (DOI: 10.1109/MEMSYS.2017.7863375). external page Online

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2016   

Invited Keynote: A. Hierlemann, "Subcellular-resolution Interfacing of Neurons to Highly Integrated CMOS Microelectrode Systems", International MicroNanoConference, December 13-14, 2016, Amsterdam, The Netherlands. external page Online

V. Viswam, R. Bounik, A. Shadmani, J. Dragas, A.J. Boos, A. Birchler, J. Müller, Y. Chen, A. Hierlemann, "High-Density CMOS Microelectrode Array System for Impedance Spectroscopy and Imaging of Biological Cells", Proceedings of the IEEE Sensors, Oct. 30 - Nov. 2, 2016, Orlando, FL, USA, pp. 1-3 (DOI: 10.1109/ICSENS.2016.7808761). external page Online

V. Viswam, Y. Chen, A. Shadmani, J. Dragas, R. Bounik, M. Radivojevic, J. Müller, A. Hierlemann, "2048 Action Potential Recording Channels with 2.4 µVrms Noise and Stimulation Artifact Suppression", Proceedings of the IEEE Biomedical Circuits and Systems Conference (BioCAS), Oct. 17-19, 2016, Shanghai, China (DOI: 10.1109/BioCAS.2016.7833750). external page Online

P.M. Misun, F. Forschler, A. Hierlemann and O. Frey. "Hanging-drop networks for in vitro dose-response studies on 3D tumor microtissues”, Proceedings of the 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 9-13, 2016, Dublin, Ireland, pp. 1621-1622, ISBN: 978-0-9798064-9-0.

V. Sessi, F. Seichepine, S. Pregl, N. Szabo, A. Hierlemann, T. Mikolajick, W. M. Weber, and U. Frey, “Integrating Bottom-Up Grown Silicon Nanowires on a CMOS Chip to Realize High-Density Transistor Arrays for Chemical Sensing”, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS), October 9-13, 2016, Dublin, Ireland, pp. 1118–1119. ISBN: 978-0-9798064-9-0.

J. Kim, S. Bürgel, D. Fluri, R. Marchan, J. Hengstler, J. Kelm, K. Renggli, A. Hierlemann, O. Frey, "Microtissues Meet Microfluidics – Perfused Tilting Device", Roche Symposium ­– Organs on a Chip: Is the end of animal testing near?, September 09, 2016, Basel, Switzerland.

P. Misun, S. Rismani Yazdi, D. Fluri, J. Kelm, K. Renggli, A. Hierlemann, O. Frey, "Microtissues Meet Microfluidics – Hanging-Drop Networks", Roche Symposium ­– Organs on a Chip: Is the end of animal testing near?, September 09, 2016, Basel, Switzerland.

A. Dudina, F. Seichepine, Y. Chen, A. Stettler, A. Hierlemann, U. Frey “Switch-matrix-based Monolithic CMOS Platform Featuring a Large Array of Carbon Nanotube Sensor Elements and a 96-channel Readout Circuitry”, Proceedings of the 30^th Eurosensors Conference , September 4-7, 2016, Budapest, Hungary, and Procedia Engineering 2016, 168, pp. 916-919 (DOI: 10.1016/j.proeng.2016.11.305). external page Online

V. Viswam, R. Bounik, A. Shadmani, J. Dragas, J. Müller, Y. Chen, A. Hierlemann, "32-Channel Integrated Electrical Impedance Sensors on a Multi-Functional Neural Microelectrode Array Platform", Proceedings of the 30^th Eurosensors Conference, September 4-7, 2016, Budapest, Hungary, and Procedia Engineering 2016, 168, pp. 510-513 (DOI: 10.1016/j.proeng.2016.11.511). external page Online

M. Fiscella, J. Müller and A. Hierlemann, “High-resolution Microelectrode Array Platform for Characterizing iPSC-derived Cells at Subcellular, Cellular, and Network Levels”, Cellular Dynamics International iForum, October 11^th, 2016, France. external page Online

S.A. Geissler, and A. Hierlemann, “Electrical Conduction Through Axons in Tunnel Culture Systems”, Society for Neuroscisnce (SfN) Meeting, 2016, San Diego, CA, USA, Program No. 469.14/NNN29. external page Online

J. Kim, P. Misun, D. Fluri, J. Kelm, K. Renggli, A. Hierlemann, O. Frey, "Microphysiological Fluidic System for Multi-Tissue Interaction and Analysis", Latsis Symposium on Personalized Medicine – Challenges and Opportunities, June 27-29, 2016, Zürich, Switzerland.

P. Misun, S. Rismani Yazdi, S. Bürgel, D. Fluri, J. Kelm, K. Renggli, A. Hierlemann, O. Frey, "Microphysiological Fluidic Hanging Drop Network for Multi-Tissue Interaction and Analysis", Organ-on-a-Chip World Congress & 3D-Cultures, July 7-8, 2016, Boston, MA, USA. external page Online

U. Frey, T. Bullmann, X. Yuan, and A. Hierlemann, “Towards High-Throughput Acquisition of Axonal-Delay Maps Using High-Density Microelectrode Arrays”, The 4th RIEC International Symposium on Brain Functions and Brain Computer, February 23-24, 2016, Sendai, Japan, pp. S1-3. external page Online

V. Viswam, J. Dragas, A. Shadmani, Y. Chen, J. Müller, A. Stettler, A. Hierlemann, "Multi-Functional Microelectrode Array System featuring 59’760 Electrodes, 2048 Electrophysiology Channels, Impedance and Neurotransmitter Measurement Units", Digest of Technical Papers of the International Solid-State Circuits Conference (ISSCC), 2016, Jan. 31 - Feb. 4, San Francisco, CA, USA, Session 22.8, pp. 394-396 (DOI: 10.1109/ISSCC.2016.7418073). external page Online

X. Yuan, S. Kim, J. Juyon, M. D'Urbino, T. Bullmann, Y. Chen, A. Stettler, A. Hierlemann, U. Frey, "A microelectrode array with 8,640 electrodes enabling simultaneous full-frame readout at 6.5 kfps and 112-channel switch-matrix readout at 20 kS/s", Proceedings of the IEEE Symposium on VLSI Circuits, 15-17 June 2016, Honolulu, HI, USA, pp. 1-2 (DOI: 10.1109/VLSIC.2016.7573558). external page Online

Invited Plenary: A. Hierlemann, "Highly integrated CMOS microsystems to interface with neurons at subcellular resolution", Joint Symposium of the 18th Annual Conference of Chinese Society of Micro-Nano Technology and Microsystems & Nanoengineering Summit 2016 (CSMNT2016 & MAN2016), Beijing, China, July 29-31, 2016. external page Online

A. Stettler, S. Bürgel, O. Frey, and A. Hierlemann, "Non-planar Electrodes Made from Bond Wires for Impedance Spectroscopy of 3D-Microtissues", Proceedings Hilton Head Workshop: A Solid-State Sensors, Actuators and Microsystems Workshop, June 5 - 9, 2016, Sonesta Resort, Hilton Head Island, South Carolina, USA. external page Online 

J. Müller, F. Franke, M. Fiscella, U. Frey, D. Bakkum, and A. Hierlemann, “Optimizing Spike-Sorting Yield through Selection of Optimal Recording Sites in High-density Microelectrode Arrays”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00122). external page Online

A. Shadmani, V. Viswam, J. Dragas, Y. Chen, R. Bounik, A. Stettler, M. Radivojevic, J. Müller, and A. Hierlemann, “A Novel Multi-Functional High-Density MEA Platform for Studying Electrogenic Cells”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00086). external page Online

M. Fiscella, K. Yonehara, A. Drinnenberg, F. Franke, J. Müller, B. Roska, and A. Hierlemann, “Screening Transgenic Mouse Models of Human Eye Diseases with CMOS High-Density Microelectrode Arrays”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00091). external page Online

V. Viswam, Y. Chen, R. Bounik, A. Shadmani, J. Dragas, J. Müller, and A. Hierlemann, “Highly Matched TΩ Pseudo-resistors for Multi-channel Neural Signal Recording Applications”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00090). external page Online

W. Gong, J. Senčar, D. Bakkum, and A. Hierlemann, “Long-term High-density Microelectrode Array Recordings Evidence Stability of Neuron Locations in Organotypic Hippocampus Slices”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00056). external page Online

S. Sitnikov, D. Jäckel, A. Hierlemann, “Studying extracellular action potential waveforms using HD MEAs”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00130). external page Online

T. Russell, F. Franke, and A. Hierlemann, “Recording From Hamster Ventral Respiratory Group Slices During Simulated Hibernation Bouts”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00024). external page Online

Bounik R, V. Viswam, A. Shadmani, J. Dragas, Müller J, Y. Chen and A. Hierlemann ,“Impedance Measurements on a Multi-functional Neural MEA Platform”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00025). external page Online

M. Radivojevic, D. Jäckel, M. Altermatt, J. Müller, V. Viswam, A. Hierlemann, and D. Bakkum, “Electrical Identification and Selective Microstimulation of Neuronal Compartments Based on Features of Extracellular Action Potentials”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00021). external page Online

R. Diggelmann, M. Fiscella, A. Drinnenberg, F. Franke, B. Roska, and A. Hierlemann, “Using High-Density MEAs For High-Throughput Retinal Ganglion Cell Type Classification”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00015). external page Online

X. Yuan, S. Kim, M. D’Urbino, J. Juyon, M.E. Obien, T. Bullmann, Y. Chen, A. Stettler, A. Hierlemann, and U. Frey, “Dual-mode-operation Microelectrode Array for Extracellular Action Potential Recording”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00014). external page Online

J. Dragas, V. Viswam, A. Shadmani, Y. Chen, A. Stettler, M. Radivojevic, J. Müller, A. Hierlemann, “Multi-Functional CMOS-HDMEA Integrating 59'760 Electrodes, 2'048 Electrophysiology Readouts, Stimulation Units, Impedance and Neurotransmitter Measurement Units”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00002). external page Online

S. Geissler, A. Hierlemann, “Tunnel Culture System to Examine Cell-Cell Interaction on Microelectrode Array”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00003). external page Online

M.E. Obien, A. Hierlemann, U. Frey, “Analyzing Recurrent Activity in Acute Cortical Slices Using High-Density Microelectrode Arrays”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00121). external page Online

S. Huber, T. Bullmann, K. Deligkaris, A. Hierlemann, and U. Frey, “Assessment of Connectivity in Neuronal Cultures by Recording from Axonal Arbors”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00077). external page Online

T. Bullmann, S. Huber, K. Deligkaris, A. Hierlemann, and U. Frey, “Temperature Effects on Neuronal Network Activity”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00096). external page Online

B. van Lier, A. Hierlemann, and F. Knoflach, “Gamma, but not Delta, Theta, and Beta Oscillation Occurrence Increases with Age of Organotypic Hippocampal Cultures”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00017). external page Online

S. Idrees, F. Franke, R. Diggelmann, A. Hierlemann, and T. Münch, “UnitBrowser - A Tool to Evaluate and Post-Process Units Sorted by Automatic Spike Sorting Algorithms”, Front. Neurosci. Conference Abstracts of the 10th International Meeting on Substrate-Integrated Electrode Arrays, 2016, Reutlingen, Germany (DOI: 10.3389/conf.fnins.2016.93.00054). external page Online

S. Bürgel, L. Diener, J. Kim, M. Pena-Francesch, O. Frey, A. Hierlemann, "Automated impedance analysis of drug impact on cancer spheroids", Book of Abstracts 3D Cell Culture 2016, April 19 - 21, Freiburg, Germany, pp. 138-139 (ISBN 978-3-89746-182-6).

Invited Plenary: A. Hierlemann, "Highly integrated CMOS microsystems to interface with neurons at subcellular resolution" Micronanosystems Workshop 2016, May 17 - 18, Lund, Sweden. external page Online

P. Misun, J. Rothe, A. Hierlemann, O. Frey, "Biosensor interface for real-time monitoring of 3D microtissue spheroids in hanging-drop networks", Book of Abstracts 3D Cell Culture 2016, April 19 - 21, Freiburg, Germany, pp. 164-165 (ISBN 978-3-89746-182-6).

O. Frey, J. Kim, A. Hierlemann, D. Fluri, J. Kelm, T. Petreus, E. Tang, R. Marchan, J. Hengstler, "Adding metabolic competence to 3D spheroid-based assays by using a microfluidic multi-tissue culturing platform", Book of Abstracts 3D Cell Culture 2016, April 19 - 21, Freiburg, Germany, pp. 27-28  (ISBN 978-3-89746-182-6).

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2015

Invited: A. Hierlemann, J. Müller, D. Bakkum, F. Franke, "Highly integrated CMOS microsystems to interface with neurons at subcellular resolution", Technical Digest IEEE International Electron Devices Meeting, 2015, Dec. 7-9, Washington, USA, pp. 13.2.1-4, ISBN: 978-1-4673-9893-0 (DOI: 10.1109/IEDM.2015.7409688). external page Online

R. Diggelmann, M. Fiscella, A. Drinnenberg, F. Franke, B. Roska, A. Hierlemann, "High-throughput identification of retinal ganglion cell types based on their light-evoked spiking patterns", Society for Neuroscience (SFN) Meeting, 2015, Chicago, USA, Program No. 450.03/DD22. external page Online

J. Müller, D.J. Bakkum, A. Hierlemann. "Connectivity analysis of whole-network recordings obtained by a high-spatiotemporalresolution microelectrode array", Society for Neuroscience (SFN) Meeting, 2015, Chicago, USA, Program No. 266.01/BB31. external page Online

F. Franke, M. Fiscella, R. Diggelmann, A. Drinnenberg, B. Roska, A. Hierlemann, "Position-dependent characteristics of retinal ganglion cell mosaics across the entire retina", Society for Neuroscience (SFN) Meeting, 2015, Chicago, USA, Program No. 147.17/K24. external page Online

W. Gong, J. Sencar, D. Jaeckel, D. Bakkum, A. Hierlemann, "Tracking the activity of multiple individual neurons over one month in organotypic hippocampal slices grown on high-density multi-electrode arrays",  Society for Neuroscience (SFN) Meeting, 2015, Chicago, USA, Program No. 540.08/CC24. external page Online

T. Bullmann, K. Deligkaris, A. Hierlemann, U. Frey, "Measurement and simulation of temperature effects on axonal conduction, synaptic transmission and network activity - Implications for the evolution of hibernation", Society for Neuroscience (SFN) Meeting, 2015, Chicago, USA, Program No. 672.11/C44. external page Online

Invited: A. Hierlemann, "Highly integrated CMOS microsystems to interface with neurons at subcellular resolution", Workshop on Computational Neuroscience and the Hybrid Brain, October 12-14, 2015, Bernstein Center, Freiburg, Germany. external page Online

M. Fiscella, F. Franke, A. Hierlemann, R.A. da Silveira, "Visual  Coding  and  Structure  of  Noise  Correlations  in  a  Population of Retinal Direction-Selective Neurons", European Retina Meeting 2015, October 1-3, Brighton, UK. external page Online

J. Kelm, D. Fluri, R. Marchan, K. Boonen, S. Hammad, B. Landuyt, J.G. Hengstler, A. Hierlemann and O. Frey, "Pro-drug activation in a dynamic microfluidic system interconnecting liver and tumor microtissues", 16th Annual Congress of the European Society for Alternatives to Animal Testing (EUSAAT), 2015, Linz, Austria, ALTEX Proceedings 2015, Volume 4(2), p. 126, ISSN 2194-0479. external page Online

J.-Y. Kim, D.A. Fluri, J.M. Kelm, A. Hierlemann and O. Frey, "Microfluidic in-vitro platform for parallel human multi-tissue interaction studies", 16th Annual Congress of the European Society for Alternatives to Animal Testing (EUSAAT), 2015, Linz, Austria, ALTEX Proceedings 2015, Volume 4(2), p. 127, ISSN 2194-0479. external page Online

S. Rismani Yazdi, S. C. Bürgel, A. Shadmani, A. Hierlemann, and O. Frey, "Integrated Pump for Hanging-Drop Networks Controlled by Human iPS-Derived Cardiac Microtissue", Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 25-29, 2015, Gyeongju, Korea, pp. 111-113, ISBN: 978-0-9798064-8-3.

A. K. Birchler, M. Berger, V. Jäggin, T. Lopes, A. Hierlemann, and O. Frey, "Seamless Combination of FACS and Microfluidic Culturing of Cell Suspensions using the Hanging Drop Network Technology",Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 25-29, 2015, Gyeongju, Korea, pp. 334-336, ISBN: 978-0-9798064-8-3.

J.-Y. Kim, T. Petreus, D. A. Fluri, J. M. Kelm, E. K. Y. Tang, A. Hierlemann and O. Frey, "96 well format-based microfludiic platform for multiorgan network using multicellular spheroids", Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 25-29, 2015, Gyeongju, Korea, pp. 747-749, ISBN: 978-0-9798064-8-3.

Z. Zhu, O. Frey, N. Haandbæk, F. Franke, F. Rudolf and A. Hierlemann, "Monitoring Cell Growth of Single Immobilized S. pombe Cells Through Electrical Impedance Spectroscopy", Proceedings of the19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 25-29, 2015, Gyeongju, Korea, pp. 63-65, ISBN: 978-0-9798064-8-3.

K. Chawla, S. C. Bürgel, G. W. Schmidt, F. Rudolf, O. Frey, A. Hierlemann, "Microfluidic Cell Culturing Platform for Parallelized Long-term, High-Resolution Imaging in Combination with Impedance Spectroscopy", Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 25-29, 2015, Gyeongju, Korea, pp. 141-143, ISBN: 978-0-9798064-8-3.

L. Diener, S. C. Bürgel, J.-Y. Kim, M. Pena-Francesch, O. Frey, and A. Hierlemann, "Automated and Parallelized Impedance Analysis of Cancer Spheroids", Proceedings of the 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), October 25-29, 2015, Gyeongju, Korea, pp. 731-733, ISBN: 978-0-9798064-8-3.

Invited: F. Franke, "Sensory Coding with Correlated Neurons", Bernstein Conference 2015, Satellite Workshop Dynamic retinal coding: Mechanisms and consequences, Sept. 14, 2015, Heidelberg, Germany. external page Online

W. Gong, M. Radivojevic, D. Jäckel, D. Bakkum and A. Hierlemann, "Long-term, high-spatiotemporal resolution recording and stimulation of hippocampal slice on high-density microelectrode arrays", Proceedings of the 7th International IEEE EMBS Conference on Neural Engineering, 2015, April 22-24, Montpellier, France. external page Online

G.W. Schmidt, O. Frey, F. Rudolf, A. Hierlemann, "Versatile and User-Friendly Microfluidics for High-Resolution Long-Term Imaging of Yeast", YEAST 2015, 6-12 September 2015, Levico Terme, Italy (DOI: 10.1002/yea.3092). external page Online

K. Chawla, S.C. Bürgel, G.W. Schmidt, F. Rudolf, O. Frey, A. Hierlemann, "Microfluidic Cell Culturing Platform Combining Long-term, High-resolution Imaging with Impedance Spectroscopy", Proceedings of Eurosensors 2015, Freiburg, Germany, and Procedia Engineering, 2015, 120, pp.154-157 (DOI: 10.1016/j.proeng.2015.08.592). external page Online

J. Lin, M. E. J. Obien, A. Hierlemann, and U. Frey, "Automated Navigation of a Glass Micropipette on a High-density Microelectrode Array", Proceedings of the 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Milan, Italy, August 25-29, 2015, pp. 881–884 (DOI: 10.1109/EMBC.2015.7318503). external page Online

G.W. Schmidt, M. Lang, O. Frey, F. Rudolf, A. Hierlemann, "A microfluidic platform for high-resolution imaging of single yeast cells with versatile environmental control", FEBS 2015, 4-9 July, 2015, Berlin, Germany. external page Online

P. Misun, J. Rothe, A. Hierlemann, O. Frey, "Real-time Multi-analyte Online Monitoring of 3D Cell Cultures by Integrated Enzyme-based Biosensors in Hanging-drop Networks", Proceedings of the 18th International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers, 2015, Anchorage, Alaska, USA, pp. 1625-1628, ISBN: 978-1-4799-8954-6 (DOI: 10.1109/TRANSDUCERS.2015.7181252). external page Online
Received Best Poster Award of external page Transducers 2015.

W. Gong, J. Sencar, D. Jäckel, J. Müller, M. Fiscella, M. Radivojevic, D. Bakkum, A. Hierlemann, "Long-term, High-spatiotemporal-resolution Recording from Cultured Organotypic Slices with High-density Microelectrode Arrays", Proceedings of the 18th International Conference on Solid-State Sensors, Actuators and Microsystems, Transducers, 2015, Anchorage, Alaska, USA, pp. 1037-1040, ISBN: 978-1-4799-8954-6 (DOI: 10.1109/TRANSDUCERS.2015.7181103). external page Online

Invited: A. Hierlemann, "CMOS Technology to Interface with Single Neurons and Axons", Special Evening Session ES2 "Brain Machine Interfaces", Digest of Technical Papers of the International Solid-State Circuits Conference (ISSCC), 2015, San Francisco, CA, USA, p. 523, ISBN: 978-1-4799-6223-5. external page Online

J. Y. Kim, D. A. Fluri, R. Marchan, K. Boonen, S. Hammad, B. Landuyt, J. G. Hengstler, J. M. Kelm, A. Hierlemann, O. Frey, "Prodrug Activation in a Dynamic Microfluidics System Interconnecting Liver and Tumor Microtissues", 54^th Annual Meeting of the Society of Toxicology, 22-26 March, 2015, San Diego, USA.

O. Frey, J.-Y. Kim, D. A. Fluri, R. Marchan, J. G. Hengstler, A. Hierlemann, J. M. Kelm, "Microtissues Meet Microfluidics: A Body on a Chip Platform Technology Based on a Highly Parallel Standard SBS Layout", 4^th Annual Conference of the Society for Laboratory Automation and Screening, Feb. 7-11, 2015, Washington, USA.

K. Deligkaris, D.J. Bakkum, A. Hierlemann and U. Frey, "Identification And Analysis Of Large Amplitude Axonal Spikes In Spontaneously-Active Neural Networks", 38th Annual Meeting of the Japan Neuroscience Society, July 28-31, 2015, Kobe, Japan, 2P368. external page Online

M. E. J. Obien, J. Lin, T. Bullmann, A. Hierlemann, and U. Frey, "Automatically guided single-cell electroporation on high-density microelectrode arrays", 38th Annual Meeting of the Japan Neuroscience Society, July 28-31, 2015, Kobe, Japan, 2O07–3–1. external page Online

T. Bullmann, K. Deligkaris, A. Hierlemann, and U. Frey, "Neurons in the Cold: from hibernating hamsters to neuronal networks on high-density CMOS arrays", 38th Annual Meeting of the Japan Neuroscience Society, July 28-31, 2015, Kobe, Japan, 2O09–3–4. external page Online

F. Seichepine, J. Rothe, A. Dudina, A. Hierlemann, and U. Frey, "Array of 1024 LG-CNTFET biosensors integrated on a CMOS microsystem", in Digest of Contributions of the 16th International Conference on the Science and Application of Nanotubes (NT15), Nagoya, Japan, 2015, p. 296.

S. C. Bürgel, Y. Schmid, I. Agarkova, D. A. Fluri, J. M. Kelm, A. Hierlemann, O. Frey, "Simultaneous Impedance Spectroscopy and Stimulation of Human IPS-derived Cardiac 3D Spheroids in Hanging-drop Networks", Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 2015, Estoril, Portugal, pp. 226-229, ISBN: 978-1-4799-7954-7 (DOI: 10.1109/MEMSYS.2015.7050928). external page Online

S. R. Yazdi, A. Shadmani, A. Hierlemann, O. Frey, "Microfluidic Hanging-drop Platform for Parallel Closed-loop Multi-tissue Experiments", Proceedings of the 28th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 2015, Estoril, Portugal, pp. 535-538, ISBN: 978-1-4799-7954-7 (DOI: 10.1109/MEMSYS.2015.7051010). external page Online

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2014

J. Müller, M. Ballini, P. Livi, Y. Chen, D. J. Bakkum, M. Radivojevic, U. Frey, A. Stettler, and A. Hierlemann, “Large-scale Recordings from Axonal Arbors of Single Neurons with CMOS based High-density Microelectrode Arrays” Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX, USA, 2014, pp. 986–988, ISBN: 978-0-9798064-7-6. external page Online

V. Viswam, D. Jäckel, I. Jones, M. Ballini, J. Muller, A. Stettler, U. Frey, F. Franke, and A. Hierlemann, “Effects of Sub-10μm Electrode Sizes on Extracellular Recording of Neuronal Cells”, Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX, USA, 2014, pp. 980–982, ISBN: 978-0-9798064-7-6. external page Online

F. Seichepine, J. Rothe, A. Dudina, A. Hierlemann, and U. Frey, “CMOS-integrated High-density Arrays of Carbon Nanotube Sensors”, Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX, USA, 2014, pp. 1835–1837, ISBN: 978-0-9798064-7-6. external page Online

O. Frey, Y. Schmid, and A. Hierlemann, "Monitoring of 3D Multi-cellular Spheroids in Hanging Drop Networks through in-situ Impedance Spectroscopy", Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX, USA, 2014, pp. 175-177, ISBN: 978-0-9798064-7-6. external page Online
 
J.-Y. Kim, D. Fluri, J. Kelm, A. Hierlemann and O. Frey, "Liver-Tumor Model based on Spheroids in Microfluidic Networks for Pharmacokinetic Studies", Proceedings of the 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), San Antonio, TX, USA, 2014, pp. 756-758, ISBN: 978-0-9798064-7-6. external page Online

J.-Y. Kim, D. Fluri, J. G. Hengstler, R. Marchan, J. M. Kelm, A. Hierlemann, O. Frey, "Microtissues meet microfluidics: A multi-parallel body on a chip concept", 9th World Congress on Alternatives and Animal Use in the Life Sciences, 2014, August 24-28, Prague, Czech Republic. ALTEX Proceedings Vol. 3, No.1, ISSN: 2194-0479. external page Online
 
J. M. Kelm, A. Stucki, J. Stucki, T. Geiser, O. Guenat, P. De Pasquale, A. Sandoz, I. Charvet, P. Passeraub, M. Chiappalone, L. Stoppini, J.-Y. Kim, D. Fluri, J. G. Hengstler, R. Marchan, M. Rimann, U. Graf, A. Hierlemann, O. Frey, "Developments towards physiologic in vitro models in Switzerland", 9th World Congress on Alternatives and Animal Use in the Life Sciences, 2014, August 24-28, Prague, Czech Republic. ALTEX Proceedings Vol. 3, No.1, ISSN: 2194-0479. external page Online
 
O. Frey, P. M. Misun, J. Rothe, and A. Hierlemann, "Real-time In-situ Lactate Monitoring in 3D Multi-Cellular Spheroid Cultures by using Enzyme-Based Biosensors in Hanging Drop Networks", Eurosensors Conference, 2014, September 7-10, Brescia, Italy, Procedia Engineering 2014, 87, pp. 96-99 (DOI: 10.1016/j.proeng.2014.11.274). external page Online

A. Stettler, P. Buchmann, J. Rothe, M. Radivojevic, and A. Hierlemann, "Development of a Reliable Packaging for CMOS-based Microelectrode Arrays by Using an Automated Setup", Eurosensors Conference, 2014, September 7-10, Brescia, Italy, Procedia Engineering 2014, 87, pp. 1402-1405 (DOI: 10.1016/j.proeng.2014.11.705). external page Online

S. Rismani Yazdi, A. Shadmani, A. Hierlemann, O. Frey, "Integration of a Peristaltic Micropump into Microfluidic Hanging Drop Networks", Proceedings of Micro and Nano Engineering Conference 2014, Sept. 22-26, Lausanne, Switzerland.

M. Radivojevic, F. Franke, J. Müller, A. Hierleman, and D. Bakkum, "Method to non-invasively study variations in waveforms and velocities between single action potentials in mammalian axons" in Society for Neuroscience (SfN) Conference, Washington DC, USA, 2014, p. 370.17. external page Online

M. E. J. Obien, A. Hierlemann, and U. Frey, “Modeling the extracellular action potentials of single neurons towards accurate source localization” in Society for Neuroscience (SfN) Conference, Washington DC, USA, 2014, p. 372.20. external page Online

D. J. Bakkum, M. Radivojevic, D. Jaeckel, F. Franke, T. L. Russell, U. Frey, H. Takahashi, and A. Hierlemann, “The axon initial segment is a strong contributor to a neuron’s local extracellular field potential” in Society for Neuroscience (SfN) Conference, Washington DC, USA, 2014, p. 372.05. external page Online

F. Seichepine, J. Rothe, A. Dudina, A. Hierlemann, and U. Frey, “Large-scale Integration of Carbon Nanotube Devices on a Switch-Matrix-based CMOS System”, Book of Abstracts MNE, 40th International Conference on Micro and Nano Engineering, Lausanne, Switzerland, 2014, p. 527.

M. E. J. Obien, A. Hierlemann, and U. Frey, “Steering a Patch-Pipette in an Acute Slice atop a High-Density Microelectrode Array”, Proceedings of the 2014 Annual Conference of Electronics, Information, and Systems Society of IEEJ, 2014, Matsue, Japan, pp. 277–280.

K. Deligkaris, F. Gunneweg, D.J. Bakkum, A. Hierlemann and U. Frey, "Mapping Extracellular Spike Shapes to Neuronal Location and Type: A Study with Microelectrode Arrays and Fluorescence Imaging", Neuro 2014, September 11-13, Yokohama, Japan, P3-379. external page Online

F. Seichepine, J. Rothe, A. Dudina, A. Hierlemann, and U. Frey, “Integration of Double Wall Carbon Nanotube Sensors on CMOS Platform”, Abstracts of the 47th Fullerenes-Nanotubes-Graphene General Symposium, 2014, Nagoya, Japan, p. 51.

M. E. J. Obien, A. Hierlemann, and U. Frey, "Can microelectrode arrays detect calcium spikes?", 9th FENS Forum, 2014, Milan, Italy, Abstr. No. 2181. external page Online

J. Müller, D. J. Bakkum, M. Radivojevic, M. Ballini, P. Livi, Y. Chen, A. Hierlemann, "Flexible Feedback Stimulation Loop(s) between Arbitrary Sets of Individual Neurons on High-Resolution CMOS-Based Microelectrode Arrays", 9th FENS Forum, 2014, Milan, Italy. external page Online

F. Franke, M. Fiscella, M. Sevelev, A. Hierlemann, B. Roska, Rava A. da Silveira, "High-Resolution Coding with Correlated Neurons: Theory and Application to Direction-Selective Retinal Ganglion Cells", Proceedings of AREADNE: Research in Encoding and Decoding of Neural Ensembles, 2014, Santorini, Greece, p.72, ISSN: 2154-6819 (online), ISSN: 2155-3203 (print). external page Online

M. Fiscella, F. Franke, J. Müller, I. L. Jones, A. Hierlemann, "Decoding of Motion Directions by Direction-Selective Retinal Cells", in Proceedings of the 9th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2014, Reutlingen, Germany, pp. 98-99, ISSN: 2199-1596. external page Online

J. Müller, M. Ballini, Y. Chen, P. Livi, M. Radivojevic, U. Frey, D. J. Bakkum, A Hierlemann, "High-Density CMOS-based Microelectrode Array Platform for Large-Scale Neuronal Network Analysis", in Proceedings of the 9th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2014, Reutlingen, Germany, pp. 244-246, ISSN: 2199-1596. external page Online

K. Reinhard, M. Mutter, M. Fiscella, J. Müller, F. Franke, A. Hierlemann, Thomas Münch, "Novel Insights into Visual Information Processing of Human Retina", in Proceedings of the 9th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2014, Reutlingen, Germany, pp. 102-103, ISSN: 2199-1596. external page Online

W. Gong, D. Jäckel, J. Müller, M. Fiscella, M. Radivojevic, D. J. Bakkum, F. Franke, F. Knoflach, B. Gähwiler, B. Roscic, T. Russell, A. Hierlemann, "Long-Term Cultivation and Recording from Organotypic Brain Slices on High-density Micro-electrode Arrays", in Proceedings of the 9th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2014, Reutlingen, Germany, pp. 335-336, ISSN: 2199-1596. external page Online

I. L. Jones, T. Russell, M. Fiscella, F. Franke, J. Müller, M. Radivojevic, A. Hierlemann, "Characterization of Mammalian Retinal Ganglion Cell Response to Voltage Stimulus", in Proceedings of the 9th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2014, Reutlingen, Germany, pp. 75-76, ISSN: 2199-1596. external page Online

D. J. Bakkum, M. Radivojevic, D. Jäckel, F. Franke, T. L. Russell, U. Frey, H. Takahashi, and A. Hierlemann, "3D Finite Element Modeling of Single Neurons and the Microelectrode Array Microenvironment", in Proceedings of the 9th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2014, Reutlingen, Germany, pp. 160–161, ISSN: 2199-1596. external page Online

D. Jäckel, J. Müller, T. L. Russell, M. Radivojevic, F. Franke, U. Frey, D. J. Bakkum, and A. Hierlemann, "Simultaneous Intra- and Extracellular Recordings using a Combined High-Density Microelectrode Array and Patch-Clamp System", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 153–155, ISSN: 2199-1596. external page Online

T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, "Functional Connectivity Estimate from Spontaneous and Stimulus Evoked Activities in Dissociated Cultured Neurons on a High-Density CMOS Microelectrode Array", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 147–148, ISSN: 2199-1596. external page Online

M. E. J. Obien, A. Hierlemann, and U. Frey, "Technique for Analysis of Purkinje Cell Sub-Cellular Functional Dynamics in Acute Cerebellar Slices Using a High-Density Microelectrode Array",  in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 88–90, ISSN: 2199-1596. external page Online

H. Takahashi, T. Mita, S. Okawa, R. Kanzaki, U. Frey, A. Hierlemann, and D. Bakkum, "Neuronal Migration and Activity in Mature Primary Cultures on a High-Density CMOS Array", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 166–167, ISSN: 2199-1596. external page Online

V. Viswam, D. Jäckel, M. Ballini, J. Müller, M. Radivojevic, U. Frey, F. Franke, and A. Hierlemann, "An Automated Method for Characterizing Electrode Properties of High-Density Microelectrode Arrays" in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 302–303, ISSN: 2199-1596. external page Online

J. Dragas, D.Jäckel, F. Franke, A. Hierlemann, "High-throughput, High-performance, Low-latency Spike-Sorting Hardware Platform", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 185-186, ISSN: 2199-1596. external page Online

M. Radivojevic, D. Jäckel, J. Müller, V. Viswam, I.L. Jones, A. Hierlemann, D. Bakkum, "Finding the most effective site for extracellular neuronal stimulation", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 60-61, ISSN: 2199-1596. external page Online

A. Shadmani, J. Müller, P. Livi, M. Ballini, Y. Chen, A. Hierlemann, "Stimulation Artifact Suppression Techniques for High-Density Microelectrode Arrays", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 326–327, ISSN: 2199-1596. external page Online

B. van Lier, A. Hierlemann, F. Knoflach, "Detecting Significant Changes in Oscillatory Power with Cluster-Based Permutation Testing", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 190-191, ISSN: 2199-1596. external page Online

M. K. Lewandowska, D. J. Bakkum, A. Hierlemann, "Axon-isolating channels on a high density microelectrode array", in Proceedings of the 9th International Meeting on Substrate-Integrated Microelectrode Arrays, 2014, Reutlingen, Germany, pp. 176-177, ISSN: 2199-1596. external page Online

T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, “Network plasticity induced by tetanic stimulation of single neurons in dissociated neuronal cultures" (分散培養神経系における単一細胞へのテタナス刺激で誘発される複数細胞の結合の可塑性), Neuro 2014, Yokohama, Japan, P3–380. external page Online

T. Mita, Y. Ishihara, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, “Functional Connectivity Estimates Based on Spontaneous and Stimulus Evoked Activity Patterns in Dissociated Cultured Neurons on a High-Density CMOS Array" (高密度 CMOS アレイ上の分散培養系の自発および誘発神経活動パターンに基づく機能ネットワークの推定), Proceedings of The Institute of Electrical Engineers of Japan Meeting, 2014, Tokyo, Japan, 2014, MBE–14–031, ISSN: 2199-1596. external page Online

J-Y. Kim, A. Hierlemann, O. Frey "Simple and Robust Platform for Spheroid Culturing", Book of Abstracts 3D Cell Culture 2014, Advanced Model Systems, Applications, Enabling Technologies, June 25-27, Freiburg, Germany, p. 132. ISBN: 978-3-89746-152-9.

O. Frey, P. Misun, A. Hierlemann "Connecting Hanging Drops in a Microfluidic Network for Compound Testing in Continuously Perfused Multi-tissue Formats", Book of Abstracts 3D Cell Culture 2014, Advanced Model Systems, Applications, Enabling Technologies, June 25-27, Freiburg, Germany, p. 47. ISBN: 978-3-89746-152-9.

J. Dragas, D. Jäckel, F. Franke and A. Hierlemann "High-Throughput Hardware for Real-Time Spike Overlap Decomposition in Multi-Electrode Neuronal Recording Systems", Proceedings of the IEEE International Symposium on Circuits and Systems (ISCAS), 2014, Melbourne, Australia, pp. 658-661. ISBN: 978-1-4799-3432-4/14 (DOI: 10.110/ISCAS.2014.6865221). external page Online

Invited: A. Hierlemann, O. Frey, D. Bakkum, Y. Chen "CMOS-Based Monolithic Microelectrode Systems for Subcellular-Resolution Electrophysiology and Sensor Applications", Mátrafüred International Conference on Electrochemical Sensors, 2014, June 15-20, Budapest, Hungary (DOI: 10.1002/elan.201480032). external page Online

Invited: A. Hierlemann, "CMOS-based monolithic microelectrode systems for subcellular-resolution electrophysiology", NERF Neurotechnology Symposium, 2014, May 5-6, Leuven, Belgium.

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2013

S. C. Bürgel, J. Y. Kim, A. Hierlemann, O. Frey, “Electrical Impedance Spectroscopy for Label-free, Continuous Monitoring of Drug Impact on 3d Tissue Spheroids”, Proceedings of the 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2013, Freiburg, Germany, pp. 1797-1799, ISBN: 978-0-9798064-6-9. external page Online

E. Matsuda, T. Mita, J. Hubert, M. Oka, D. Bakkum, U. Frey, H. Takahashi, and T. Ikegami, “Multiple Time Scales Observed in Spontaneously Evolved Neurons on High-density CMOS Electrode Array”, Proceedings of the Twelfth European Conference on the Synthesis and Simulation of Living Systems, Advances in Artificial Life, ECAL 2013, Taormina, Italy, September 2-6 2013, pp. 1075-82, ISBN: 9780262317092. external page Online

D. J. Bakkum, U. Frey, M. Radivojevic, T. L. Russel, J. Mueller, M. Fiscella, H. Takahashi, and A. Hierlemann, “Electrical imaging of axon function”, 3rd International Symposium Frontiers in Neurophotonics, Bordeaux, France, 2013, p. 25. external page Online

M. K. Lewandowska, D. J. Bakkum, A. Hierlemann, “Microfluidic Channels for the Study of Axonal Properties on CMOS Microelectrode Array”, IEEE EMBS Conference on Neural Engineering (NER), San Diego, USA, 2013, ISSN: 1948-3546. external page Online

M. Lewandowska, D. Bakkum, A. Hierlemann, “Axonal isolation channels on a high density microelectrode array”, Society for Neuroscience (SfN) Conference, San Diego, USA, 2013, p. 783.08. external page Online

Z. Zhu, O. Frey, D. Ottoz, F. Rudolf and A. Hierlemann, “Comparative Microfluidic Culturing of Immobilized Single Cells with on-site Fluorescent-Protein Induction”, Proceedings of the 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2013, Freiburg, Germany, pp. 1713-1715, ISBN: 978-0-9798064-6-9.

O. Frey, P. M. Misun and A. Hierlemann, "Hanging Microfluidics:
 A Highly Versatile Platform for Production and Cultivation of 3D Spherical Microtissues", 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS), 2013, Freiburg, Germany, pp. 2016-2018, ISBN: 978-0-9798064-6-9.  

M. E. J. Obien, A. Hierlemann, and U. Frey, “Blind localization of single neurons in acute brain slices for subcellular-resolution analysis through a combination of a high-density microelectrode array and patch clamp”, Society for Neuroscience (SfN) Conference, San Diego, USA, 2013, p. 783.11. external page Online

M. E. J. Obien, A. Hierlemann, and U. Frey, “Factors Affecting Blind Localization of a Glass Micropipette Using a High-Density Microelectrode Array” Proceedings of IEEE Sensors, Baltimore, MD, USA, 2013, pp. 932–935, ISBN: 978-1-4673-4642-9. external page Online

D. J. Bakkum, U. Frey, M. Radivojevic, J. Mueller, M. Fiscella, H. Takahashi, and A. Hierlemann, “Local differences in axonal action potential conduction velocity”, Society for Neuroscience (SfN) Conference, San Diego, USA, 2013, p. 520.04. external page Online

M. Ballini, J. Müller, P. Livi, Y.Chen, U. Frey, A. Shadmani, I. L. Jones, W. Gong, M. Fiscella, M. Radivojevic, D. J. Bakkum, A. Stettler, F. Heer and A. Hierlemann, "A 1024-Channel CMOS Microelectrode-Array System with 26'400 Electrodes for Recording and Stimulation of Electro-active Cells In-vitro", Digest of Technical Papers of Symposium on VLSI Circuits, 2013, Kyoto, Japan, pp. C54-C55, ISBN: 978-4-86348-348-4. external page Online

M. Fiscella, F. Franke, K. Farrow, I. L. Jones, J. Müller, B. Roska, A. Hierlemann, "Decoding the Activity of ON-OFF Direction-Selective Retinal Ganglion Cells", European Retina Meeting, 2013, Alicante, Spain. (DOI: 10.12751/nncn.bc2013.0110). external page Online

F. Hilti, S.C. Bürgel, O. Frey, N. Haandbæk, A. Hierlemann, "Microdevice for Impedance Monitoring of Single Cell Electroporation", in Book of Abstracts MNE, 39th International Conference on Micro and Nano Engineering, London, UK, 2013, p. 114.

F. Seichepine, A. Dudina, S. Kim, A. Hierlemann, and U. Frey,"Semi-sacrificial Electrode Dielectrophoresis for Large-Scale Integration of Carbon Nanotubes onto a CMOS-integrated Switch-Matrix System", in Book of Abstracts MNE, 39th International Conference on Micro and Nano Engineering, London, UK, 2013, p. 207.

N. Haandbaek, S. C. Bürgel, F. Rudolf, F. Heer and A. Hierlemann, "Microfluidic Impedance Cytometer for Characterization of Subcellular Morphology of Single Cells", Proceedings of the 17th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2013, Barcelona, Spain, pp. 1314-1317, ISBN: 978-1-4673-5983-2/13 (DOI: 10.1109/Transducers.2013.6627018). external page Online

Z. Zhu, O. Frey, N. Haandbaek, D. S. Ottoz, F. Rudolf and A. Hierlemann, "Real-time Multi-parameter Monitoring of Immobilized Single Yeast Cells via Electrical Impedance Spectroscopy", Proceedings of the 17th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2013, Barcelona, Spain, pp. 1527-1530, ISBN: 978-1-4673-5983-2/13 (DOI: 10.1109/Transducers.2013.6627072). external page Online

J. Müller, M. Ballini, P. Livi, Y. Chen, A. Shadmani, U. Frey, I. L. Jones, M. Fiscella, M. Radivojevic, D. J. Bakkum, A. Stettler, F. Heer and A. Hierlemann, "Conferring Flexibility and Reconfigurability to a 26'400 Microelectrode CMOS Array for High Throughput Neural Recordings", Proceedings of the 17th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2013, Barcelona, Spain, pp. 744-747, ISBN: 978-1-4673-5983-2/13 (DOI: 10.1109/Transducers.2013.6626873).  external page Online

P. Livi, M. Wipf, A. Tarasov, R. Stoop, K. Bedner, J. Rothe, Y. Chen, A. Stettler, C. Schönenberger and A. Hierlemann, "Silicon Nanowire Ion-Sensitive Field-Effect Transistor Array Integrated with a CMOS-based Readout Chip", Proceedings of the 17th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2013, Barcelona, Spain, pp. 1751-1754, ISBN: 978-1-4673-5983-2/13 (DOI: 10.1109/Transducers.2013.6627126). external page Online

J. Dragas, D. Jäckel, F. Franke and A. Hierlemann, "An Unsupervised Method for On-Chip Neural Spike Detection in Multi-Electrode Recording Systems", Proceedings of the 35th Annual International Conference of the IEEE EMBS, Osaka, Japan, 2013, pp. 2535-2538. ISSN: 1557-170X (DOI: 10.1109/EMBC.2013.6610056). external page Online

E. Matsuda, T. Mita, J. Hubert, D. Bakkum, U. Frey, A. Hierlemann, H. Takahashi, and T. Ikegami, "Analysis of neuronal cells of dissociated primary culture on high-density CMOS electrode array", Proceedings of the 35th Annual International Conference of the IEEE EMBS, Osaka, Japan, 2013, pp. 1045–1048. ISSN: 1557-170X (DOI: 10.1109/EMBC.2013.6609683) external page Online

M. E. J. Obien, A. Hierlemann, and U. Frey, "Blind Localization of a Stimulation Electrode Using a High-Density Microelectrode Array", Proceedings of the 35th Annual International Conference of the IEEE EMBS, Osaka, Japan, 2013, SaB08.8, ISSN: 1557-170X. external page Online

M. E. Obien, A. Hierlemann, and U. Frey, "High-Resolution Recording and Analysis of Complex Spike Responses in Cerebellar Purkinje Cells with Monoplanar and Multiplanar Dendrites", Neuro 2013, June 20-23, Kyoto, Japan, 2013, P3-2-250. external page Online

T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, "Estimation of Neuronal Somata Location and Methods Toward Neuronal Network Analysis of Dissociated Cultured Neurons on High-Density CMOS Microelectrode Arrays", Neuro 2013, June 20-23, Kyoto, Japan, 2013, P3-2-248. external page Online

K. Deligkaris, S. Kim, D. J. Bakkum, A. Hierlemann, and U. Frey, "Dynamics of Multiple Interconnected Neuronal Populations Cultured on a High-Density Microelectrode Array System", Neuro 2013, June 20-23, Kyoto, Japan, 2013, P1-2-222. external page Online

Invited: U. Frey, M. Fiscella, D. Jaeckel, and A. Hierlemann, "CMOS-based Microelectrode Arrays for High-Resolution Electrophysiology of the Retina", 2nd HD Physiology International Symposium, Tokyo, Japan, 2013, p. 24.

S. Okawa, T. Mita, D. Bakkum, A. Hierlemann, U. Frey, R. Kanzaki and H. Takahashi, "Time dependent co-variation of neural network configuration and activity in matured dissociated cultures (成熟した培養神経回路のネットワーク形状と活動の経時変化)", Proceedings of The Institute of Electrical Engineers of Japan Meeting, Tokyo, Japan, 2013, pp. 97–102.

Invited Plenary: A. Hierlemann, "CMOS-based monolithic microsensor systems for biological applications", Proceedings of the 8th German BioSensor Symposium, March 11-13, 2013, TH Wildau, Germany, PV10 p.39. external page Online

Invited: A. Hierlemann, "Direct Interfacing of Neuronal Ensembles with CMOS Microelectronics", 1^st Bernstein Sparks Workshop on Cortical Neurointerfaces, March 06 – 10, 2013, Hanse-Wissenschaftskolleg, Delmenhorst, Germany. external page Online

Invited: A. Hierlemann, "CMOS-based monolithic micro- and nanosensor systems", Swiss NanoConvention, May 23-24, 2013, Congress Center Basel, Switzerland. external page Online

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2012

S. C. Bürgel, C. Escobedo, S. Kemmerling, N. Sauter, N. Haandbæk, O. Frey, A. Hierlemann, “Combined Microfluidic, Single-cell Electroporation and Impedance Spectroscopy Analysis”, Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), 2012, Okinawa, Japan, pp. 410-412, ISBN: 978-0-9798064-5-2. external page Online

D. J. Bakkum, U. Frey, J. Mueller, M. Fiscella, B. Roscic, H. Takahashi, A. Hierlemann, "Capability of an 11,011-electrode CMOS array to study action potential propagation plasticity", Annual Meeting of the Society for Neuroscience (SfN), 2012, New Orleans, USA 322.07. external page Online

D. Jäckel, D. J. Bakkum, M. Radivojevic, J. Müller, M. Fiscella, U. Frey, F. Franke, A. Hierlemann, "Using extracellular high-resolution microelectrode array recordings to estimate intracellular features of cultured neurons", Annual Meeting of the Society for Neuroscience (SfN), 2012, New Orleans, USA. external page Online

O. Frey, S. Mohanty, W. Moritz, A. Hierlemann, "Microfluidic platform for drug development based on 3D spherical microtissues", EMBL Conference: Microfluidics 2012, Heidelberg, Germany, July 25-27, 2012, p. 72

F. Franke, P. Meier, A. Sobolev, E. Hagen, A. Hierlemann, K. Obermayer, G.T. Einevoll, T. Wachtler, "Automatic spike sorting evaluation: A website based community approach", 5th INCF Congress of Neuroinformatics 2012, Munich, Germany (DOI: DOI:10.3389/conf.fninf.2014.08.00050). external page Online

P. Meier, F. Franke, E. Hagen, G.T. Einevoll, K. Obermayer, "A simulation framework for acute extracellular recordings" , 5th INCF Congress of Neuroinformatics 2012, Munich, Germany (DOI: 10.3389/conf.fninf.2014.08.00037). external page Online

E. Hagen, T. Ness, A. Khosrowshahi, F. Franke, G.T. Einevoll, "Modeling realistic extracellular recordings of neuronal populations for the purpose of evaluating automatic spike-sorting algorithms" , 5th INCF Congress of Neuroinformatics 2012, Munich, Germany (DOI: 10.1186/1471-2202-13-S1-P143). external page Online

D. Jäckel, F. Franke, U. Frey, A. Hierlemann, "Simulator for Realistic High-Density Microelectrode Array Signals", 5th INCF Congress of Neuroinformatics 2012, Munich, Germany (DOI: 10.3389/conf.fninf.2014.08.00022). external page Online

J. Dragas, D. Jäckel, F. Franke, A. Hierlemann, "FPGA implementation of a template matching-based real-time spike sorter for extracellular multi-electrode recordings of neural signals", 5th INCF Congress of Neuroinformatics 2012, Munich, Germany (DOI: 10.3389/conf.fninf.2014.08.00007). external page Online

P. Meier, F. Franke, E. Hagen, G.T. Einevoll, K. Obermayer, "A simulation framework for acute extracellular recordings", Bernstein Conference on Computational Neuroscience 2012, Munich, Germany. external page Online

E. Hagen, T. Ness, A. Khosrowshahi, F. Franke, G.T. Einevoll, "Modeling realistic extracellular spiking activity in populations of neurons for the purpose of evaluating automatic spike-sorting algorithms", Twenty First Annual Computational Neuroscience Meeting: CNS, 2012, p. 143, Decatur, GA, USA (DOI: 10.1186/1471-2202-13-S1-P143). external page Online

T. Mita, D. J. Bakkum, N. Tanada, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, "Physiological Characteristics of Neurons and the Observed Action Potentail by High Density CMOS Array (高密度 CMOS アレイの観測電位と神経細胞の生理学的特性)", in Proceedings of The Institute of Electrical Engineers of Japan Meeting, Hirosaki, Japan, 2012, pp. 88–93.

K. Deligkaris, J. Kaneko, M. Fiscella, I. L. Jones, M. Engelene, A. Hierlemann, M. Takahashi, and U. Frey, "Detecting Light Response Patterns of rd1 Mouse Retinae: Electrophysiological and Optical Challenges", in Proceedings of The Institute of Electrical Engineers of Japan Meeting, Hirosaki, Japan, 2012, pp. 1747–1748.

J. Rothe, O. Frey, A. Stettler, Y. Chen, A. Hierlemann, "CMOS chip for electrochemical monitoring of the metabolic activity of biological cells", in Proceedings of IEEE Sensors Conference, 2012, Taipei, Taiwan. (DOI: 10.1109/ICSENS.2012.6411351). external page Online

P. Livi, V. A. Guzenko, J. Rothe, A. Stettler, Y. Chen, A. Hierlemann, "Monolithic system featuring a gold nanowire array on a CMOS chip for biosensing applications", in Proceedings of IEEE Sensors Conference, 2012, Taipei, Taiwan. (DOI: 10.1109/ICSENS.2012.6411299). external page Online

P. Livi, S. Rigante, Y. Chen, A. M. Ionescu, A. Hierlemann, "A hybrid finFET-based biosensor with integrated readout capability", in Proceedings of the 26th European Conference on Solid-State Transducers (Eurosensors), 2012, Krakow, Poland, Procedia Engineering Vol. 47, 2012, ISSN: 1877-7058 (DOI: 10.1016/j.proeng.2012.09.273). external page Online

F. Franke, D. Jäckel, A. Hierlemann, "High performance spike sorting for HDMEA recordings", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 218-219, ISSN: 2194-5519. external page Online

M. Ballini, J. Mueller, P. Livi, Y. Chen, U. Frey, F. Heer, A. Stettler, A. Hierlemann, "A 1024-channel 26k-electrode, low noise, CMOS microelectrode array for in-vitro recording and stimulation of electrogenic cells at high resolution", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 272-273, ISSN: 2194-5519. external page Online

V. Viswam, M. Ballini, V. Jagannadh, R. Branka, J. Mueller, J. David, A. Hierlemann, "High Resolution Bio Impedance Imaging and spectroscopy with CMOS based Micro Electrode Arrays", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 284-285, ISSN: 2194-5519. external page Online

M. Fiscella, K. Farrow, I. L. Jones, D. Jäckel, J. Müller, U. Frey, D. J. Bakkum, B. Roska, A. Hierlemann, "Targeting Defined Populations of Retinal Ganglion Cells with CMOS Microelectrode Arrays", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 114-116, ISSN: 2194-5519. external page Online

E. Masi, M. Fiscella, J. Müller, U. Frey, S. Mancuso, A. Hierlemann, "Investigating Electrical Network Dynamics in Plant Root Cells by Means of a High-Density CMOS-based Microelectrode Array", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 246-247, ISSN: 2194-5519. external page Online

M, Radivojevic, D. Jäckel, J. Müller, M. Fiscella, U. Frey, B. Roscic, A. Hierlemann, D. J. Bakkum, "Methods for Long-term High-resolution Characterization of In Vitro Developing Neuronal Networks Grown over High-density CMOS-based Microelectrode Arrays", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 68-69, ISSN: 2194-5519. external page Online

K. Deligkaris, J. Kaneko, M. Fiscella, J. Müller, I. L. Jones, A. Hierlemann, M. Takahashi, U. Frey, "Light Response Patterns in Silenced rd1 Mice Retinal Ganglion Cells", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 126-127, ISSN: 2194-5519. external page Online

D. J. Bakkum, U. Frey, J. Müller, M. Fiscella, B. Roscic, H. Takahashi, A. Hierlemann, "Capabilities of a High-Density CMOS Microelectrode Array to Identify, Record, and Stimulate Individual Neurons in Cultured Networks", in Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 206-207, ISSN: 2194-5519. external page Online

J. Dragas, D. Jäckel, F. Franke, A. Hierlemann, "Hardware implementation, optimisation and performance analysis of a real-time spike sorter for high-density microelectrode recordings", Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 232-233, ISSN: 2194-5519. external page Online

J. Mueller, D. J. Bakkum, B. Roscic, A. Hierlemann, "A flexible system to provide sub-millisecond feedback stimulation loops between multiple sets of individually identifiable neurons", Proceedings of the 8th International Meeting on Substrate-Integrated Micro Electrode Arrays, 2012, Reutlingen, Germany, pp. 76-77, ISSN: 2194-5519. external page Online

Y. Ishihara, T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, H. Takahashi, "Navigation of stimulation microelectrode for intracellular stimulation on high density CMOS array", Conference of Japanese Society for Medical and Biological Engineering (JSMBE), Fukuoka, Japan.

Invited: D. J. Bakkum, U. Frey, J. Mueller, M. Fiscella, H. Takahashi, A. Hierlemann, "Towards an ideal interface to neural cultures: recording and stimulation via high-density CMOS electrode arrays", Medical Physics and Biomedical Engineering (MPBE) World Congress, Beijing, China, 2012, May 26th: TH.16/01.1-1. ISBN: 978-3-642-29305-4. external page Online

S. Rigante, P. Livi, A. Rusu, Y. Chen, A Hierlemann, A. M. Ionescu, "Hybrid dg-mosfets integrated circuits for enhanced ionic and biological sensing applications", Proceedings 22nd Anniversary World Congress on Biosensors, May 15-18, 2012, Cancun, Mexico, oral 3-B2. external page Online

S.C. Bürgel, N. Haandbæk, O. Frey, A. Hierlemann, "Characterization of cell clusters by electric impedance spectroscopy", Proceedings 22nd Anniversary World Congress on Biosensors, May 15-18, 2012, Cancun, Mexico, P1.23. external page Online

M.K. Lewandowska, O. Frey, D.J. Bakkum, A. Hierlemann, "Integrated microfluidic neuronal culture chamber on high density CMOS MEA", Proceedings 22nd Anniversary World Congress on Biosensors, May 15-18, 2012, Cancun, Mexico, oral 3-B1. external page Online

C. Escobedo, S. C. Bürgel, S. Kemmerling, Z. Zhu, M. Gerspach, A. Stettler, O. Frey, A. Hierlemann, "On-chip cell lysis via corona discharge", Proceedings 22nd Anniversary World Congress on Biosensors, May 15-18, 2012, Cancun, Mexico, P2.112. external page Online

Z. Zhu, O. Frey, N. Haandbæk, L. Lei, A. Stettler, A. Hierlemann, "Microfluidic chip for array-based cultivation and continuous electric impedance spectroscopy monitoring of single yeast cells", Proceedings 22nd Anniversary World Congress on Biosensors, May 15-18, 2012, Cancun, Mexico, P2.72. external page Online

S. C. Bürgel, Z. Zhu, N. Haandbæk, O. Frey, A. Hierlemann, "Dynamic and static impedance spectroscopy for single particle characterization in microfluidic chips", Proceedings of the 24th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 2012, Paris, France, pp. 1033-1036, ISBN: 978-978-1-4673-0325-5. (DOI: 10.1109/MEMSYS.2012.6170247). external page Online

Invited: Douglas J. Bakkum, U. Frey, J. Mueller, M. Fiscella, H. Takahashi, A. Hierlemann, "Uncovering neuronal cellular and network function using a high-density 11,011-microelectrode CMOS array", Swiss Society for Neuroscience Annual Meeting, February 2012, Zurich; Symposium: "Advances in neuromorphic systems". external page Online

Invited Keynote: A Hierlemann, "Microtechnology for microtissue handling and analysis", Book of Abstracts, 3D Cell Culture, Advanced Model Systems, Applications & Enabling Technologies, March 14-16, 2012, Zurich, p. 6. external page Online

O. Frey, Z. Schumacher and A. Hierlemann, "Microfluidic approaches and impedance spectroscopy for screening of spherical microtissues", Book of Abstracts, 3D Cell Culture, Advanced Model Systems, Applications & Enabling Technologies, March 14-16, 2012, Zurich, p. 81. external page Online

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2011

Z. Schumacher, O. Frey and A. Hierlemann, "Microfluidic Impedance Spectroscopy Scanner for Spherical Microtissues", Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Seattle, Washington, USA, pp. 1731-1733, ISBN: 978-0-9798064-4-5. external page Online

Z. Zhu, O. Frey and A. Hierlemann, "Microfluidic Single-Cell Culture Chip for Individual Trapping, Cultivation, and Selective Release of Yeast Cells", Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Seattle, Washington, USA, pp. 136-138, ISBN: 978-0-9798064-4-5. external page Online

N. Haandbaek, K. Mathwig, R. Streichan, N. Goedecke, S. Bürgel, F. Heer and A. Hierlemann, "Characterization of Cell Phenotype Using Dynamic Vision Sensor and Impedance Spectroscope", Proceedings of the 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Seattle, Washington, USA, pp. 1236-1238, ISBN: 978-0-9798064-4-5. external page Online

D. J. Bakkum, U. Frey, J. Mueller, M. Fiscella, H. Takahashi, A. Hierlemann, "Advancing neuronal cellular and network analysis using a high-density 11,011-microelectrode CMOS array", International Brain Research Organization (IBRO), 2011, Florence, Italy. (DOI: 10.5214/ans.0972.7531.180411). external page Online

M. Fiscella. I. L. Jones, D. Jäckel, J. Müller, U. Frey, K. Farrow, B. Roska and A. Hierlemann, "Recording of Light Induced Neural Activity of Mouse Retinal Ganglion Cells on a CMOS-Integrated High-Density Microelectrode Array", Proceedings of the European Retina Meeting (ERM), 2011, Amsterdam, The Netherlands, pp. 92. external page Online

S. Truax, K.S. Demirci, L. Beardslee, Y. Luzinova, B. Mizaikoff, A. Hierlemann, O. Brand, "Effect of polymer thickness on the chemical sensing behavior of polymer-coated mass-sensitive disk resonators", Proceedings of the 24th IEEE International Conference on Micro Electro Mechanical Systems (MEMS), 2011, Cancun, Mexico, pp. 853-856. ISBN: 978-1-4244-9632-7. (DOI: 10.1109/MEMSYS.2011.5734559). external page Online

D. Jäckel, U. Frey, M. Fiscella, and A. Hierlemann, "Blind Source Separation for Spike Sorting of High Density Microelectrode Array Recordings", Proceedings of the 5th International IEEE EMBS Conference on Neural Engineering, 2011, Cancun, Mexico, pp. 5-8. ISBN: 978-1-4244-4140-2. (DOI: 10.1109/NER.2011.5910476). external page Online

S. Rigante, P. Livi, A. Hierlemann, A. M. Ionescu, "A simulation study of N-shell silicon nanowires as biological sensors", Proceedings of the 12th IEEE International Conference on Ultimate Integration on Silicon (ULIS), March 14-16, 2011, Cork, Ireland, pp. 1-4. ISBN: 978-1-4577-0090-3. (DOI: 10.1109/ULIS.2011.5758003). external page Online

U. Frey, U. Egert, and A. Hierlemann, "CMOS-based Microelectrode Arrays for High-Resolution, Non-Invasive Electrophysiology", 50th Annual Conference of the Japanese Society for Medical and Biological Engineering (JSMBE), April 29 - May 1, 2011, Tokyo, Japan, Transactions of the JSMBE, Vol. 49.1, pp. 77, ISSN: 1347-443X. external page Online

D. Jäckel, J. Müller, M.U. Khalid, U. Frey, D.J. Bakkum, and A. Hierlemann "High-Density Microelectrode Array System and Optimal Filtering for Closed-Loop Experiments", Proceedings of the 16th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2011, Beijing, China, pp. 1200-1203. ISBN: 978-1-4577-0157-3. (DOI: 10.1109/TRANSDUCERS.2011.5969314). external page Online  

I.L. Jones, M. Fiscella, U. Frey, D. Jäckel, J. Müller, B. Roscic, R. Streichan, A. Hierlemann, "Recording of Neural Activity of Mouse Retinal Ganglion Cells by Means of an Integrated High-density Microelectrode Array", Proceedings of the 16th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2011, Beijing, China, pp. 186-189. ISBN: 978-1-4577-0157-3 (DOI: 10.1109/TRANSDUCERS.2011.5969341). external page Online  

O. Frey, J. Rothe, M.K. Lewandowska, P.D. van der Wal, N.F. de Rooij, and A. Hierlemann, "Multi-site Monitoring of Choline and Glutamate Using Biosensor Microprobe Arrays in Combination with CMOS Circuitry", Proceedings of the 16th IEEE International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, 2011, Beijing, China, pp. 1829-1832. ISBN: 978-1-4577-0157-3 (DOI: 10.1109/TRANSDUCERS.2011.5969298). external page Online

T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, "Measurement of Action Potentials of Dissociated Cultured Neurons by High Density CMOS Array and Network Analysis", Proceedings of the 34th Annual Meeting of the Japan Neuroscience Society, 2011, Yokohama, Japan, pp. P4–v08 (DOI: 10.1016/j.neures.2011.07.1813). external page Online

T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, "Functional Network Analysis of Dissociated Cultured Neurons at High Spatial Resolution", Annual Conference of Electronics, Information and Systems Society, September 2011, Toyama, Japan, GS6-3, pp.1305-1310.

T. Mita, D. J. Bakkum, U. Frey, A. Hierlemann, R. Kanzaki, and H. Takahashi, "Comparison of Functional Network by Conditional Firing Probability and Mutual Information", Papers of Technical Meeting on Medical and Biological Engineering, March 2011, Japan, MBE-11-026-038, pp. 1-6.

U. Frey, D. Jäckel, M. Fiscella, and A. Hierlemann, "Spike Sorting Techniques for High-Resolution Microelectrode Array Recordings", in Proceedings of the 26th Symposium on Biological and Physiological Engineering (BPES), Shiga, Japan, 2011, pp. 131–134.

M. Fiscella, I.L. Jones, D. Jäckel, J. Müller, U. Frey, K. Farrow, B. Roska, A. Hierlemann, "Recording of Light Induced Neural Activity of Mouse Retinal Ganglion Cells on an Integrated High-density Microelectrode Array", Abstract Book 1st International SystemsX.ch Conference on Systems Biology, Oct 24th – 26th, 2011, Basel, Switzerland, p.142. ISBN: 978-3-909386-21-5. external page Online
Received Best Student Poster Award.

S. Kemmerling, J. Ziegler, G. Schweighauser, S. Arnold, D. Giss, S.A. Müller, P. Ringler, K.N. Goldie, N. Goedecke, A. Hierlemann, H. Stahlberg, A. Engel, T. Braun, "Towards Visual Proteomics by Electron Microscopy: Vision, Developments and Preliminary Results", Abstract Book 1st International SystemsX.ch Conference on Systems Biology, Oct 24th – 26th, 2011, Basel, Switzerland, p.150. ISBN: 978-3-909386-21-5. external page Online

N. Haandbaek, K. Mathwig, R. Streichan, N. Goedecke, S. Bürgel, F. Heer and A. Hierlemann, "Bandwidth Compensation for High Resolution Impedance Spectroscopy", Proceedings Eurosensors XXV, September 4-6, 2011, Athens, Greece (DOI: 10.1016/j.proeng.2011.12.298). external page Online

R. Gutierrez-Osuna, R. Gosangi, A. Hierlemann, "Advances in Active and Adaptive Chemical Sensing", Proceedings of the 14th International Symposium on Olfaction and Electronic Nose, May 02-05, 2011, New York, USA, Volume: 1362, Pages: 11-12. ISBN: 978-0-7354-0920-0 (DOI: 10.1063/1.3626288). external page Online

F. Franke, D. Jäckel, P. Meier, U. Frey, M. Fiscella, A. Hierlemann, K. Obermayer, "Spike sorting for multielectrode arrays", Annual Meeting of the Society for Neuroscience (SfN), 2011, Washington DC, USA. external page Online

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2010

O. Frey, J. Rothe, M. Lewandowska, F. Heer, T. Holtzman, J.W. Dalley, P.D. van der Wal, A. Hierlemann, N.F. de Rooij, "Towards multi-site monitoring of neurotransmitters in freely moving animals using biosensor microprobe arrays combined with CMOS electronics", 13th International Conference on In Vivo Methods: Monitoring Molecules in Neuroscience, Brussels, Belgium, 2010, pp. 160-162. external page Online

P. Livi, F. Heer, U. Frey, D. J. Bakkum, and A. Hierlemann, "Compact Voltage and Current Stimulation Buffer for High-Density Microelectrode Arrays", Proceedings of the IEEE International Solid-State Circuits Conference, ISSCC, San Francisco, USA, 2010, pp. 240 – 241, 2010, ISSN 0193-6530, ISBN: 978-1-4244-6034-2 (DOI: 10.1109/TBCAS.2010.2080676). external page Online

M. Fiscella, U. Frey, D. Jäckel, J. Müller, R. Streichan, I. L. Jones, B. Roscic, K. Farrow, B. Roska, A. Hierlemann, "Recording of Neural Activity of Mouse Retinal Ganglion Cells by Means of an Integrated High-Density Microelectrode Array", in FENS Abstr., vol.5, 019.10, 2010, Amsterdam, The Netherlands. external page Online

A. Hierlemann, "Microtechnology: Enabling Technology for Systems Biology", 16th Annual World Micromachine Summit, April 26-30, 2010, Dortmund, Germany. external page Online

M.K. Lewandowska, J. Rothe, F. Heer, M. Josowicz, J. Janata, A Hierlemann, "Characterization of label-free DNA hybridization sensor array in CMOS technology", Proceedings of the 20th Anniversary World Congress on Biosensors, May 26-28, 2010, Glasgow, United Kingdom, P3.1.059.

M. Fiscella, U. Frey, D. Jäckel, J. Müller, R. Streichan, I. Jones, B. Roscic, C. Farrow, B. Roska, A. Hierlemann, "Recording of Neural Activity of Mouse Retinal Ganglion Cells by Means of an Integrated High Density Microelectrode Array", Proceedings of the 7th International meeting on substrate-integrated micro electrode arrays, 2010, Reutlingen, Germany, p. 106-107, ISBN: 3-938345-08-5. external page Online

D. Jäckel, U. Frey, J. Müller, I. Jones, U. Khalid, J. Sedivy, A. Hierlemann, "Online Spike Extraction for Bidirectional High-Density Microelectrode Arrays using Optimal Filters", Proceedings of the 7th International meeting on substrate-integrated micro electrode arrays, 2010, Reutlingen, Germany, p. 201-202, ISBN: 3-938345-08-5. external page Online

P. Livi, F. Heer, U. Frey, D. Bakkum, A. Hierlemann, "Voltage and Current Stimulation Buffer for High-Density Microelectrode Arrays", Proceedings of the 7th International meeting on substrate-integrated micro electrode arrays, 2010, Reutlingen, Germany, p. 340-341, ISBN: 3-938345-08-5. external page Online

D. Bakkum, U. Frey, J. Müller, M. Fiscella, H. Takahashi, A. Hierlemann, "Novel neuronal cellular and network measurements enabled by a high-density 11'011-Microelectrode CMOS Array", Proceedings of the 7th International meeting on substrate-integrated micro electrode arrays, 2010, Reutlingen, Germany, p. 324-326, ISBN: 3-938345-08-5. external page Online

D. Bakkum, U. Frey, T. Mita, J. Müller, M. Fiscella, H. Takahashi, A. Hierlemann, "Neuronal cellular and network analysis using a high-density 11'011-electrode CMOS Array", 33rd Annual meeting of the Japan Neuroscience Society, 2010, Kobe, Japan, oral contribution O2-10-2-4 (DOI: 10.1016/j.neures.2010.07.235). external page Online

Invited: A. Hierlemann, "Microtechnology and microelectronics for non-invasive electrophysiology at subcellular resolution", International Conference on Microplate Technology (MipTec), 2010, Basel, Switzerland. external page Online

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2009

Invited Plenary: A. Hierlemann, "CMOS-Based Bio/Chemosensor and Bioelectronic Microsystems", Book of Abstracts Eurosensors XXIII, Lausanne, Switzerland, 2009, p. 48, ISSN: 1876 61 96 (DOI: 10.1016/j.proche.2009.07.002). external page Online

B. Roscic, M. Fiscella, J. Pereira, F. Faraci, U. Frey, J. Relvas, and A. Hierlemann, "Neurobiological Studies on Cultured Neuronal and Glial Networks Using Micro Electrode Arrays (MEA)", in Abstracts of the USGEB, 2009 Meeting, Interlaken, Switzerland, 2009, T6–39. external page Online

Invited: A. Hierlemann, "Highly Integrated Biosensor and Bioelectronic Microsystems in CMOS Technology", Pittsburgh Conference, March 8-13, Chicago, IL, 2009, Abstract 650-2. external page Online

Invited: Andreas Hierlemann, U. Frey, F. Heer, S. Hafizovic, "CMOS-Based High-Density Microelectrode Arrays for Subcellular Resolution Recordings", Proceedings of the 8th Göttingen Meeting of the German Neuroscience Society, 32nd Göttingen Neurobiology Conference, March 25-29, Göttingen, Germany, 2009, Abstract S20-4, ISSN: 0947-0875. external page Online

Invited: A. Hierlemann, P. Kurzawski, V. Schurig, "The use of different transduction principles for qualitative and quantitative chiral gas analysis", 215th Electrochemical Society Meeting, May 24-29, San Francisco, CA, USA, 2009, Meeting Abstracts, Abstract 1546, ISSN: 1091-8213. (DOI: 10.1149/1.3118556). external page Online

U. Frey, U. Egert, D. Jäckel, J. Sedivy, M. Ballini, P. Livi, F. Faraci, F. Heer, S. Hafizovic, B. Roscic, and A. Hierlemann,"Depth Recording Capabilities of Planar High-Density Microelectrode Arrays", Proceedings of the 4th International IEEE EMBS Conference on Neural Engineering, Antalya, Turkey, 2009, pp. 207–210, ISBN: 978-1-4244-2073-5 (DOI: 10.1109/NER.2009.5109270). external page Online

Invited: U. Frey and A. Hierlemann, "High-Density Microelectrode Array in CMOS Technology Applied to Acute Brain Slice Recordings and to Gene-Function Studies", Proceedings of the 3rd IEEE International Workshop on Advances in Sensors and Interfaces, Trani, Italy, 2009, p. 7 (DOI: 10.1109/IWASI.2009.5184758). external page Online

T. Lanz, S. Hafizovic, J. Rothe, R. Streichan, N. Goedecke, F. Heer A. Hierlemann, "Differential Impedance Spectrometer and Vision System for the Analysis of Single Cells", Proceedings of the 15th International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, Denver, CO, USA, June 21-25, 2009, 1297-1300, ISBN: 978-1-4244-4193-8 (DOI: 10.1109/SENSOR.2009.5285868). external page Online

U. Frey, U. Egert, F. Heer, S. Hafizovic, and A. Hierlemann, "Subcellular-Resolution Recording of Electrical Activity Using a CMOS-Microelectrode System", Proceedings of the 15th International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, Denver, CO, USA, June 21-25, 2009, 1674-1677, ISBN: 978-1-4244-4193-8. (DOI: 10.1109/SENSOR.2009.5285753). external page Online

S. Truax, K.S. Demirci, A. Hierlemann, O. Brand, "Exploring the Resolution of Different Disk-Type Chemical Sensors", Proceedings of the 15th International Conference on Solid-State Sensors, Actuators & Microsystems, Transducers, Denver, CO, USA, June 21-25, 2009, 1838-1841, ISBN: 978-1-4244-4193-8 (DOI: 10.1109/SENSOR.2009.5285703) external page Online

A. Perera, A. Pardo, D. Barrettino, A. Hierlemann, S. Marco, "Evaluation of fish spoilage by means of a single metal oxide sensor under temperature modulation", Proceedings 13th International Symposium on Olfaction and the Electronic Nose, ISOEN, Brescia, Italy, April 15-17, 2009, AIP Conference Proceedings, Volume1137, pages: 483-486, ISBN: 978-0-7354-0674-2 (DOI: 10.1016/j.snb.2009.11.037). external page Online

D. J. Bakkum, U. Frey, J. Mueller, M. Fiscella, A. Hierlemann, and H. Takahashi, "Accessing neuronal network activity with an 11,011 electrode CMOS array", Proc. of the 24th Symposium on Biological and Physiological Engineering, Sendai, Japan, pp. 27–28, 2009. Received 'Young Investigators' Award (Society of Instrument and Control Engineers). external page Online

D. J. Bakkum, U. Frey, A. Hierlemann, and H. Takahashi, "Subcellular-resolution electronic recording and stimulation of cultured cortical networks using an 11,011 electrode CMOS array", Proceedings of the 32nd Annual Meeting of the Japan Neuroscience Society, Nagoya, Japan , O2–I5–2, 2009.

J. Šedivý, U. Frey, D. Jäckel, and A. Hierlemann, "Independent-Component-Analysis-Based Spike Sorting Algorithm for High-Density Microelectrode Array Data Processing", Proceedings of the IEEE Sensors Conference, Christchurch, New Zealand, Vol. 1, pp. 384 – 386, 2009, ISBN: 978-1-4244-5335-1. external page Online

D. J. Bakkum, U. Frey, J. Mueller, M. Fiscella, A. Hierlemann, and H. Takahashi, "Subcellular-resolution electronic recording and stimulation of cultured cortical networks using an 11,011 electrode CMOS array", in Society for Neuroscience Conference, 2009, Chicago, USA, p. 390.23/HH31, 2009. external page Online

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2008

F. Heer, M. Keller, G. Yu, J. Janata, M. Josowicz, A. Hierlemann, "CMOS electro-chemical DNA detection array with on-chip ADC", Proceedings of the IEEE International Solid-State Circuits Conference, ISSCC, San Francisco, USA, 2008, p. 168, 169, and 604, ISBN: 978-1-4244-2010-0. (DOI: 10.1109/ISSCC.2008.4523110). external page Online

S. Truax, K.S. Demirci, J.H. Seo, P. Kurzawski, Y. Luzinova, A. Hierlemann, B. Mizaikoff, O. Brand, "Gas and liquid phase sensing of volatile organics with disk microresonator", Proceedings of the 21st IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2008), Tucson, AZ, 2008, p 220-223, ISBN: 978-1-4244-1792-6 (DOI: 10.1109/MEMSYS.2008.4443632). external page Online  

Invited Keynote: A. Hierlemann, U. Frey, S. Hafizovic, F. Heer, "CMOS-based bioelectronics and microelectrode arrays", Proc. of the 6th International meeting on substrate-integrated micro electrode arrays, 2008, Reutlingen, Germany, p. 236-239, ISBN: 3-938345-05-5 (DOI: 10.1016/j.proche.2009.07.002). external page Online

U. Frey, U. Egert, J. Sedivy, F. Heer, S. Hafizovic, A. Hierlemann, "High-resolution CMOS-based microelectrode array and its application to acute slice preparations", Proc. of the 6th International meeting on substrate-integrated micro electrode arrays, 2008, Reutlingen, Germany, p. 291-292, ISBN: 3-938345-05-5. external page Online

C. Diaz, U. Frey, J. Kelm, A. Hierlemann, M. Fussenegger, "Modulation of cardiomyocyte electrical properties by regulated BMP-2 expression", Proc. of the 6th International meeting on substrate-integrated micro electrode arrays, 2008, Reutlingen, Germany, p. 175-177, ISBN: 3-938345-05-5. external page Online

A. Antamonico, N. Goedecke, R. Streichan, M. Heinemann, R. Zenobi, "Mass-spectrometric approach to single-cell yeast analysis", 3rd International Workshop on approaches to Single-Cell Analysis, 2008, Zurich, Switzerland.
Received Best Poster Award.

R. Streichan, N. Goedecke, F. Faraci, F. Heer, S. Hafizovic, A. Hierlemann, "Microsystem for Single-Cell Metabolomics", 3rd International Workshop on approaches to Single-Cell Analysis, 2008, Zurich, Switzerland (DOI: 10.1109/SENSOR.2007.4300233). external page Online

S. Truax, K.S. Demirci, J.H. Seo, P. Kurzawski, Y. Luzinova, A. Hierlemann, B. Mizaikoff, O. Brand, "Sensing of volatile organics with disk microresonators", Book of Abstracts Eurosensors XXII, Dresden, Germany, 2008, p. 181, ISBN: 978-3-00-025218-1. external page Online

N. Goedecke, F. Faraci, F. Heer, S. Hafizovic, R. Streichan, A. Hierlemann, "Microfluidic device for continuous-flow cell lysis", Book of Abstracts Eurosensors XXII, Dresden, Germany, 2008, p. 735, ISBN: 978-3-00-025218-1. external page Online

P. Kurzawski, A. Bogdanski, V. Schurig, R. Wimmer, A. Hierlemann. "Capacitive microsensors to identify the enantiomers of methyl propionates and to assess their purity", Book of Abstracts Eurosensors XXII, Dresden, Germany, 2008, p. 1277, ISBN: 978-3-00-025218-1. external page Online

F. Heer, M. Keller, G. Yu, J. Janata, M. Josowicz, A. Hierlemann, "CMOS electro-chemical DNA detection array", Book of Abstracts Eurosensors XXII, Dresden, Germany, 2008, p. 1443, ISBN: 978-3-00-025218-1. external page Online

U. Frey, C. Diaz, J. Sedivy, J. M. Kelm, M. Fussenegger, A. Hierlemann, "CMOS-based microelectrode array for gene-function studies", Book of Abstracts Eurosensors XXII, Dresden, Germany, 2008, p. 1456, ISBN: 978-3-00-025218-1. external page Online

Invited: A. Hierlemann, "CMOS-based biosensors and bioelectronics", Booklet of Abstracts, International Workshop on micro/nanoelectronics: devices and technologies for biomedical applications, sponsored by the U.S. National Science Foundation and the Interuniversity Microelectronics Center (IMEC), 2008, Leuven, Belgium.

Invited: A. Hierlemann, U. Frey, F. Heer, S. Hafizovic, "CMOS-based bioelectronic microsystems", The 19th Micromechanics Europe Workshop, 2008, Aachen, Germany, p. 243-246, ISBN: 978-3-00-025529-8. external page Online

Invited: F. Heer, A. Hierlemann, "Integrated Biosensors and Bioelectronics in CMOS Technology", Proceedings of the 34th International Conference on Micro- and Nanoengineering, Athens, Greece, 2008, p. 129 (contribution 6C5). external page Online

Invited: U. Frey, M. Graf, S. Taschini, K.-U. Kirstein, and A. Hierlemann, "Digital Systems Architecture to Accommodate Wide Range Resistance Changes of Metal-Oxide Sensors", Proceedings of the 7th IEEE International Conference on Sensors, 2008, Lecce, Italy, p. 593-595, ISBN: 978-1-4244-2581-5 (DOI: 10.1109/ICSENS.2008.4716509). external page Online

N. Goedecke, R. Streichan, F. Heer, S. Hafizovik, A. Hierlemann, "Microfluidic System for Single-Cell Analysis", 22nd International Symposium on MicroScale Bioseparations & Methods for Systems Biology, Berlin, Germany, 2008 (DOI:10.1016/j.chroma.2008.07.085). external page Online

R. Streichan, N. Goedecke, J. Rothe, F. Faraci, F. Heer, S. Hafizovic, A. Hierlemann, "Microsystem for Single-Cell Metabolomics", Nanotech, 2008, Montreux, Switzerland.

Invited: Andreas Hierlemann, "CMOS-based bio/chemosensor and bioelectronic microsystems", Booklet 3rd International SGVC-Workshop on Microbioreactors in R&D for Fine Chemicals and Pharmaceutical Production, 2008, LONZA, Visp, Switzerland, p. 10-29 (DOI:10.1016/j.proche.2009.07.002). external page Online

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2007

Invited: U. Frey, J. Sedivy, F. Heer, S. Hafizovic, A. Hierlemann, "Interfacing with Neurons at High Spatio-temporal Resolution", Proceedings of the 6th IEEE International Conference on Sensors, 2007, Atlanta, USA, p. 1113-1115, ISBN: 1-4244-1262-5 (DOI: 10.1109/ICSENS.2007.4388601). external page Online

Chunguang Jin, Edward T. Zellers, Petra Kurzawski, Andreas Hierlemann, "A Comparison of Multi-Transducer Arrays and Single-Transducer Arrays for the Determination of Multi-Vapor Mixtures", Proceedings of the 6th IEEE International Conference on Sensors, 2007, Atlanta, USA, p. 1217-1220, ISBN: 1-4244-1262-5 (DOI: 10.1109/ICSENS.2007.4388628). external page Online

J. Sedivy, U. Frey, F. Heer, S. Hafizovic, A. Hierlemann, "Multi-Chip High-Density Microelectrode System for Electrogenic-Cell Recording and Stimulation", Proceedings of the 6th IEEE International Conference on Sensors, 2007, Atlanta, USA, p. 716-719, ISBN: 1-4244-1262-5 (DOI: 10.1109/ICSENS.2007.4388500). external page Online

Urs Frey, Carlota Diaz Sanchez-Bustamante, Tanja Ugniwenko, Flavio Heer, Jan Sedivy, Sadik Hafizovic, Branka Roscic, Martin Fussenegger, Axel Blau, Ulrich Egert, Andreas Hierlemann, "Cell Recordings with a CMOS High-Density Microelectrode Array", Proceedings of the 29th IEEE EMBS Annual International Conference, 2007, Lyon, France, p. 167-170, ISBN: 1-4244-0788-5 (DOI: 10.1109/IEMBS.2007.4352249). external page Online

Flavio Heer, Sadik Hafizovic, Urs Frey, Branka Roscic, Tanja Ugniwenko, Axel Blau, Andreas Hierlemann, "Using Microelectronics Technology to Communicate with Living Cells", Proceedings of the 29th IEEE EMBS Annual International Conference, 2007, Lyon, France, p. 6081-6084, ISBN: 1-4244-0788-5 (DOI: 10.1109/IEMBS.2007.4353736). external page Online

S. Hafizovic, F. Heer , U. Frey, T. Ugniweniko, A. Blau, C. Ziegler, A. Hierlemann, "A CMOS-based microelectrode array for information processing with natural neurons", Proceedings of the 3rd IEEE EMBS Conference on Neural Engineering, 2007, Hawaii, USA, 692-695, ISBN: 1-4244-0792-3 (DOI: 10.1109/CNE.2007.369767). external page Online

S. Hafizovic, F. Heer, U. Frey, T. Ugniwenko, A. Blau, C. Ziegler, A. Hierlemann, "Bio-microelectronic information processing device consisting of natural neurons on a CMOS microsystems", Proceedings of the IEEE Transducers, 2007, Lyon, France, p. 1223-1226, ISBN: 1-4244-0841-5 (DOI: 10.1109/SENSOR.2007.4300357). external page Online

P. Kurzawski, A. Hierlemann, "Chiral discrimination performance of a monolithic CMOS gas sensor microsystem", Proceedings of the IEEE Transducers, 2007, Lyon, France, p. 2545-2548, ISBN: 1-4244-0841-5 (DOI: 10.1109/SENSOR.2007.4300690). external page Online

C. Vancura, K.-U. Kirstein, Y. Li, F. Josse, A. Hierlemann, "Equivalent-circuit model for CMOS-based resonant cantilever biosensors", Proceedings of the IEEE Transducers, 2007, Lyon, France, p. 1733-1736, ISBN: 1-4244-0841-5 (DOI: 10.1109/SENSOR.2007.4300487). external page Online

N. Goedecke, R. Toelke, F. Heer, A. Hierlemann, "Microsystem for single-cell metabolomics", Proceedings of the IEEE Transducers, 2007, Lyon, France, p. 727-730, ISBN: 1-4244-0841-5 (DOI: 10.1109/SENSOR.2007.4300233). external page Online

U. Frey, F. Heer, R. Pedron, S. Hafizovic, F. Greve, J. Sedivy, K-U. Kirstein, A. Hierlemann, "11k-Electrode, 126-Channel, High-Density Microelectrode Array to Interact with Electrogenic Cells", Digest of Technical Papers, ISSCC, IEEE International Solid-State Circuits Conference, San Francisco, USA, 2007, p. 158-159, and 593, ISSN: 0193-6530 (DOI: 10.1109/ISSCC.2007.373636). external page Online

U. Frey, F. Heer, R. Pedron, F. Greve, S. Hafizovic, K.-U. Kirstein, A. Hierlemann, "11’000 Electrode-, 126 Channel-CMOS Microelectrode Array for Electrogenic Cells". Proceedings IEEE MEMS, 2007, Kobe, Japan, 2007, p. 541-544, ISSN: 1084-6999 (DOI: 10.1109/MEMSYS.2007.4433154). external page Online

Invited: S. Hafizovic, F. Heer, U. Frey, J. Sedivy, F. Greve, A. Hierlemann, "CMOS-based microelectrode arrays for interacting with neurons", Proceedings of the 8th International Conference on Ultimate Integration on Silicon, ULIS, 2007, Leuven, Belgium, p. 92-95. external page Online

Invited Plenary: A. Hierlemann, "Chemosensors, biosensors, and microsystems based on standard semiconductor technology (CMOS)", Proceedings of the 5th IASTED International Conference on Biomedical Engineering, Innsbruck, Austria, 2007, p. 1-5, ACTA Press, (ISBN: 978-0-88986-648-5). external page Online

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2006

Stéphane Kühne, Markus Graf, Antonio Tricoli, Hektor Meier, Felix Mayer, Sotiris E. Pratsinis, Andreas Hierlemann, "CMOS-compatible wafer-level fabrication of microsensors with flame-spray-pyrolysis-deposited gas-sensitive layers", Proceedings of the 20th Eurosensors, 2006, Gothenburg, Sweden, 274-275, ISBN: 91-631-9280-2. external page Online

P. Kurzawski and A. Hierlemann, "Applications and Performance of a Polymer-coated Monolithic CMOS Gas Sensor Microsystem", Proceedings of the 20th Eurosensors, 2006, Gothenburg, Sweden, 228-229, ISBN: 91-631-9280-2. external page Online

F. Greve, J. Lichtenberg, K. U. Kirstein, U. Frey, A. Hierlemann, "A perforated CMOS microchip for cell immobilization and monitoring of electrogenic cells", Proceedings of the 20th Eurosensors, 2006, Gothenburg, Sweden, 286-287, ISBN: 91-631-9280-2 (DOI: 10.1088/0960-1317/17/3/007). external page Online
Received Best Paper Award Eurosensors 2006.

Invited: Andreas Hierlemann, "Interfacing microelectronics with chemistry and living cells", (Keynote),Proceedings of the 20th Eurosensors, 2006, Gothenburg, Sweden, 244-245, ISBN: 91-631-9280-2. external page Online

S. Hafizovic, F. Heer, A. Hierlemann, "Signal processing chain for CMOS microelectrode arrays interfaced to electrogenic cells", Proceedings of the 5th Int. meeting on substrate-integrated microelectrodes, 2006, Reutlingen, Germany, p. 210-211, ISBN: 3-938345-02-0. external page Online

F. Heer, S. Hafizovic, W. Franks, U. Frey, F. Greve, A. Blau, T. Ugniwenko, C. Ziegler, A. Hierlemann, "CMOS integrated bidirectional 128-electrode array for electrogenic cells", Proceedings of the 5th Int. meeting on substrate-integrated microelectrodes, 2006, Reutlingen, Germany, p. 212-213, ISBN: 3-938345-02-0. external page Online

Invited: A. Hierlemann, "Microelectronics technology for chemo/biosensors", Digest of the International Conference on Microtechnologies in Medicine and Biology, Bankoku-Shinryokan, Okinawa, Japan, 2006, p.7, ISBN: 1-4244-0338-3 (DOI: 10.1109/MMB.2006.251469). external page Online

F. Greve, L. Seemann, S. Bonneick, J. Lichtenberg, A. Hierlemann, "High-throughput cell-based screening system with on-chip dilution stage", Digest of the International Conference on Microtechnologies in Medicine and Biology, Bankoku-Shinryokan, Okinawa, Japan, 2006, p.28, ISBN: 1-4244-0338-3 (DOI: 10.1109/MMB.2006.251525). external page Online

F. Heer, S. Hafizovic, W. Franks, U. Frey, F. Greve, T. Ugniwenko, A. Blau, C. Ziegler, A. Hierlemann, "CMOS Integrated Bidirectional 128-Electrode Array for Electrogenic Cells", Abstracts of the EPFL Latsis Symposium, 2006, Lausanne, Switzerland, p. 87-88, ISBN: 978-2-8399-0134-5. external page Online

N. Goedecke, R. Tölke, O. Frey, K.U. Kirstein, and A. Hierlemann, "Microfluidic System for Single-Cell Metabolomics", Nanotech, 2006, Montreux, Switzerland 2006.

S. Hafizovic, F. Heer, W. Franks, F. Greve, A. Blau, C. Ziegler, and A. Hierlemann, "CMOS Integrated Bidirectional 128-Electrode Array for Electrogenic Cells", Technical Digest of the IEEE MEMS, 2006, Istanbul, Turkey, p. 4-7, ISBN: 0-7803-9475-5. external page Online

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2005

P. Kurzawski, T. Salo, A. Hierlemann, "Towards a versatile DRIE: Silicon pit structures combined with electrochemical etch stop", Technical Digest, IEEE-MEMS, 2005, Miami, FL, USA, p. 504-507, ISBN: 0-7803-8732-5 (DOI: 10.1109/MEMSYS.2005.1453977). external page Online

S. Hafizovic, T. Volden, D. Barrettino, K.-U. Kirstein, A. Hierlemann, "Single-chip atomic force microscope", Technical Digest, IEEE-MEMS, 2005, Miami, FL, USA, p. 638-641, ISBN: 0-7803-8732-5 (DOI: 10.1109/MEMSYS.2005.1454010). external page Online

Invited: A. Hierlemann, "CMOS-based chemical sensors", CD of Abstracts Pittcon, 2005, Orlando, FL, USA, Abstract 80-1. external page Online

K.U. Kirstein, J. Sedivy, T. Salo, C. Hagleitner, C. Vancura, A. Hierlemann, "A CMOS-based tactile sensor for continuous blood pressure monitoring", Proceedings of the "Design, Automation and Test 2005 in-Europe” (DATE), 2005, Munich, Germany, 210-14 (DOI: 10.1109/DATE.2005.4). external page Online

K.-U. Kirstein, Y. Li, M. Zimmermann, C. Vancura, T. Volden, W. H. Song, J. Lichtenberg, A. Hierlemannn, "Cantilever-Based Biosensors in CMOS Technology", Proceedings of the "Design, Automation and Test in-Europe" (DATE), 2005, Munich, Germany, 1340-1341 (DOI: 10.1109/DATE.2005.90). external page Online

J. Lichtenberg, A. Hierlemann, "Liquid-core piezoresistive fully polymer-based pressure sensor", Proceedings IEEE Transducers, Seoul, Korea, 2005, 491-494, ISBN: 0-7803-8994-8 (DOI: 10.1109/SENSOR.2005.149646). external page Online

C. Vancura, Y. Li, K.U. Kirstein, F. Josse, A. Hierlemann, J. Lichtenberg, "Fully integrated CMOS resonant cantilever sensor for biochemical detection in liquid environments", Proceedings IEEE Transducers, Seoul, Korea, 2005, 640-643, ISBN: 0-7803-8994-8 (DOI: 10.1109/SENSOR.2005.1496498). external page Online

Invited: A. Hierlemann, "Integrated chemical microsensor systems in CMOS-technology", Proceedings IEEE Transducers, Seoul, Korea, 2005, 1134-1137, ISBN: 0-7803-8994-8 (DOI: 10.1109/SENSOR.2005.1497276). external page Online

Y. Li, C. Vancura, D. Barrettino, M. Graf, C. Hagleitner, A. Kummer, M. Zimmermann, K.U. Kirstein, A. Hierlemann, "Monolithic CMOS multi-transducer gas sensor microsystem", Proceedings IEEE Transducers, Seoul, Korea, 2005, 1142-1145, ISBN: 0-7803-8994-8 (DOI: 10.1109/SENSOR.2005.1497278). external page Online

F. Greve, J. Lichtenberg, K.U. Kirstein, U. Frey, A. Hierlemann, "Perforated CMOS microchip platform for immobilization and activity monitoring of electrogenic cells", Proceedings IEEE Transducers, Seoul, Korea, 2005, 1745-1747, ISBN: 0-7803-8994-8 (DOI: 10.1109/SENSOR.2005.1497429). external page Online

W.H. Song, J. Lichtenberg, A. Hierlemann, "Dead-end injection molding of polymeric microcantilever arrays", Proceedings IEEE Transducers, Seoul, Korea, 2005, 2040-2043, ISBN: 0-7803-8994-8 (DOI: 10.1109/SENSOR.2005.1497503). external page Online

G. Romera-Guereca, J. Lichtenberg, A. Hierlemann, D. Poulikakos, "Micro platform for investigation of explosive vaporization in micro TAS enclosures", Proceedings of 2005, Ninth International Conference on Miniaturized Systems for Chemistry and Life Sciences, Boston, USA, 2005, p. 1137-1139, ISBN: 0-9743611-1-9. external page Online

G. Romera-Guereca, J. Lichtenberg, A. Hierlemann, D. Poulikakos, "Explosive vaporization in micro enclosures", Proceedings of the ECI International Conference on Heat Transfer and Fluid Flow in Microscale, 2005, Castelvecchio Pascoli, Italy (DOI: 10.1016/j.expthermflusci.2006.03.012). external page Online

O. Frey, A. Hierlemann, J. Lichtenberg, "Microfluidic multi-channel system for polymerase chain reaction with integrated liquid handling", TAS 2005, Ninth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTas), Boston, USA, 2005, p.79-81, ISBN: 0-9743611-1-9. external page Online

C. Vancura, Y. Li, J. Lichtenberg, F. Josse, A. Hierlemann, "Detection of volatile organic compounds in liquid environments using fully integrated CMOS resonant cantilevers", Proceedings of Ninth International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTas), Boston, USA, 2005, p. 1170-1172, ISBN: 0-9743611-1-9. external page Online

F. Heer, S. Hafizovic, W. Franks, T. Ugniwenko, A. Blau, C. Ziegler, A. Hierlemann, "Fully integrated 128-electrode CMOS chip for bidirectional interaction with electrogenic cells", Proceedings Eurosensors XIX, Barcelona, Spain, 2005, Vol. II, WB 12. external page Online

F. Heer, S. Hafizovic, W. Franks, T. Ugniwenko, A. Blau, C. Ziegler, A. Hierlemann, "CMOS microelectrode array for bidirectional interaction with neuronal networks", Proceedings of ESSCIRC 2005, Grenoble, France, 2005, p. 335-338, ISBN: 0-7803-9205-1 (DOI: 10.1109/JSSC.2006.873677). external page Online
Received 2005 ESSCIRC Best Young Scientist Presentation Award

Invited: A. Hierlemann, “CMOS platform technology for chemical and biosensors”, Proceedings 7th Dresdner Sensor Symposium, 2005, Dresden, Germany, Dresdner Beiträge zur Sensorik, Vol. 27, 2005, TUD press, p. 41-47, ISBN: 3-938863-29-3.

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2004

M. Graf, S. Taschini, P. Käser, C. Hagleitner, A. Hierlemann, H. Baltes, "Digital MOS-transistor-based microhotplate array for simultaneous detection of environmentally relevant gases", IEEE-MEMS 2004, Maastricht, NL, 351-354, ISBN: 0-7803-8265-X (DOI: 10.1109/MEMS.2004.1290594). external page Online

D. Barrettino, M. Graf, S. S. Taschini, C. Hagleitner, A. Hierlemann, H. Baltes, "A Single-Chip CMOS Micro-Hotplate Array for Hazardous Gas Detection and Material Characterization", Proceedings of the IEEE International Solid-State Circuits Conference (ISSCC), San Francisco, USA, 2004, pp. 312-313 (DOI: 10.1109/ISSCC.2004.1332719). external page Online

D. Barrettino, M. Graf, K.U. Kirstein, A. Hierlemann, and H. Baltes, "A Monolithic Fully-Differential CMOS Gas Sensor Microsystem for Microhotplate Temperatures up to 450°C", Proceedings IEEE International Symposium on Circuits and Systems (ISCAS), Vancouver, Canada, 2004, Vol. 4, pp. 888-891 (DOI: 10.1109/ISCAS.2004.1329147). external page Online

F. Heer, W. Franks, I. McKay, S. Taschini, A. Hierlemann, H. Baltes, "CMOS Microelectrode Array for Extracellular Stimulation and Recording of Electrogenic Cells", Proceedings IEEE International Symposium on Circuits and Systems (ISCAS), Vancouver, Canada, 2004, Vol. 4, pp. 53-56 (DOI: 10.1109/ISCAS.2004.1328938). external page Online

F. Heer, W. Franks, A. Blau, S. Hafizovic, F. Greve, S. Taschini, C. Ziegler, A. Hierlemann, H. Baltes, "CMOS microchip for recording and stimulation of electrogenic cells", 4th International Meeting on Substrate-integrated Microelectrode Arrays, Reutlingen, 2004, Technical Program, p. 60.

H. Baltes, A. Blau, P. Bonifazi, K. Brander, O. Dubochet, W. Franks, F. Greve, F. Heer, S. Hafizovic, T. Hessler, A. Hierlemann, B. Kochte-Clemens, S. Koster, T. Kraus, C. Leister, N.F. de Rooij, E. Ruaro, V. Torre, C. Ziegler, "A new Platform for Studying Information Processing by Natural Neural Networks", 4th International Meeting on Substrate-integrated Microelectrode Arrays, Reutlingen, 2004, Technical Program, p. 20.

D. Barrettino, S. Hafizovic, T. Volden, J. Sedivy, K.U. Kirstein, A. Hierlemann and H. Baltes, "CMOS Monolithic Atomic Force Microscope", Proceedings IEEE Symposium on VLSI Circuits, Hawaii, USA, 2004, pp. 306-309 (DOI: 10.1109/VLSIC.2004.1346597). external page Online

Invited: A. Hierlemann, "CMOS Toolbox for Monolithic Chemical Microsensor Systems", Proceedings 10th International Meeting on Chemical Sensors, Tsukuba, Japan, 2004 and Chemical Sensors, Vol. 20, Supplement B (2004) p. 112-113 (DOI: 10.1109/SENSOR.2005.1497276). external page Online

M. Graf, D. Barrettino, K.U. Kirstein, H. Baltes, A. Hierlemann, "Metal-oxide-based Monolithic CMOS Microhotplate System for Operating Temperatures up to 500°C", Proceedings 10th International Meeting on Chemical Sensors, Tsukuba, Japan, 2004 and Chemical Sensors, Vol. 20, Supplement B (2004) p. 114-115.

P. Kurzawski, C. Hagleitner, V. Schurig, H. Baltes, A. Hierlemann, "Applications and Performance of a Polymer-coated Monolithic CMOS Gas Sensor Microsystem", Proceedings 10th International Meeting on Chemical Sensors, Tsukuba, Japan, 2004 and Chemical Sensors, Vol. 20, Supplement B (2004) p. 116-117.

C. Vancura, Yue Li, C. Hagleitner, A. Hierlemann, H. Baltes, "Detection of Volatile Organic Compounds Using a New Integrated Single-chip CMOS Cantilever Gas Sensor with Magnetic Actuation", Proceedings 10th International Meeting on Chemical Sensors, Tsukuba, Japan, 2004 and Chemical Sensors, Vol. 20, Supplement B (2004) p. 190-191.

T. Salo, P. Kurzawski, A. Hierlemann, H. Baltes, "Novel Micromachining Sequence to Improve Performance and Yield of Calorimetric Microsensors", Proceedings 10th International Meeting on Chemical Sensors, Tsukuba, Japan, 2004 and Chemical Sensors, Vol. 20, Supplement B (2004) p. 320-321.

W. Franks, S. Tosatti, A. Hierlemann, M. Textor, H. Baltes, "Biomimetic Self-assembled Surfaces for Highly Selective Guided Cell Growth on Cell-based Biosensors", Book of Abstracts, 8th World Congress on Biosensors, Granada, Spain, 2004, P. 2.5.6. external page Online

F. Greve, J. Lichtenberg, H. Hall, A. Hierlemann, H. Baltes, "Microfluidic PDMS Channel System to Achieve Defined Neuronal Network Topologies for Reliable Electrical Activity Measurements", Book of Abstracts, 8th World Congress on Biosensors, Granada, Spain, 2004, P 1.3.39. external page Online

U. Frey, M. Graf, S. Taschini, K.-U. Kirstein, C. Hagleitner, A. Hierlemann, H. Baltes, "A digital CMOS Microhotplate Array for Analysis of Environmentally Relevant Gases", Proceedings IEEE ESSCIRC, Leuven, Belgium, 2004, p. 299-302, ISBN: 0-7803-8480-6 (DOI: 10.1109/ESSCIR.2004.1356677). external page Online

T. Volden, D. Barrettino, S. Hafizovic, K.-U. Kirstein, A. Hierlemann, H. Baltes, "Single.chip AFM array with integrated digital controllers", Proc. IEEE Sensors, Vienna, 2004, 1228-1231, ISBN: 0-7803-8693-0.

Invited: Y. Li, C. Vancura, D. Barrettino, M. Graf, C. Hagleitner, A. Kummer, K.-U. Kirstein, A. Hierlemann, "Advanced chemical microsensor systems in CMOS technology", Proc. IEEE Sensors, Vienna, 2004, 24-27, ISBN: 0-7803-8693-0.

M. Graf, M. Graf, U. Frey, P. Reichel, S. Taschini, N. Bârsan, U. Weimar, and A. Hierlemann, "Monitoring of Environmentally Relevant Gases by a Digital Monolithic Metal-Oxide Microsensor Array", Proc. IEEE Sensors, Vienna, 2004, 776-779, ISBN: 0-7803-8693-0.

F. Greve, J. Lichtenberg, A. Hierlemann, "Precise cell placement by pneumatic anchoring", Proc. IEEE Sensors, Vienna, 2004, 80-82, ISBN: 0-7803-8693-0.

W. Franks, F. Heer, S. Tosatti, S. Hafizovic, P. Seif. M. Textor, A. Hierlemann, "CMOS biosensor with guided cell growth", Proc. IEEE Sensors, Vienna, 2004, 1014-1017, ISBN: 0-7803-8693-0.

C. Vancura, J. Lichtenberg, A. Hierlemann, "Characterization of resonant CMOS micro cantilevers in viscous fluids", Proc. Nanochemical Sensors Workshop (2004) 15-16.

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2003

M. Graf, D. Barrettino, S. Taschini, C. Hagleitner, A. Hierlemann, H. Baltes, "Monolithic metal-oxide microsensor system in industrial CMOS technology", Proceedings IEEE MEMS, Kyoto, Japan, (2003) 303-306, ISBN: 0-7803-7744-3 (DOI: 10.1109/MEMSYS.2003.1189746). external page Online

D. Barrettino, M. Graf, M. Zimmermann, C. Hagleitner, A. Hierlemann, H. Baltes, "A micro-hotplate-based monolithic CMOS gas sensor array", Proceedings IEEE ISCAS, Bangkok, Thailand, (2003) Vol 4, p. 852-855 (DOI: 10.1109/ISCAS.2003.1206354). external page Online

C. Hagleitner, D. Barrettino, A. Hierlemann, O. Brand, H. Baltes, "Interface circuitry for CMOS-based monolithic gas sensor arrays", Proceedings IEEE ISCAS, Bangkok, Thailand, (2003) Vol. 3, p. 542-545 (DOI: 10.1109/ISCAS.2003.1205076). external page Online

D. Barrettino, M. Graf, S. Taschini, M. Zimmermann, C. Hagleitner, A. Hierlemann, H. Baltes, "Hotplate-based conductometric monolithic CMOS gas sensor system", IEEE VLSI Symposium, Kyoto, Japan, (2003), 157-160, ISBN: 4-89114-034-8 (DOI: 10.1109/VLSIC.2003.1221188). external page Online

W. Franks, F. Heer, I. McKay, S. Taschini, R. Sunier, C. Hagleitner, A. Hierlemann, H. Baltes, "CMOS monolithic microelectrode array for stimulation and recording of natural neural networks", Proceedings IEEE Transducers, Boston, MA, USA, (2003), 963-966, ISBN: 0-7803-7731-1 (DOI: 10.1109/SENSOR.2003.1216927). external page Online

M. Graf, D. Barrettino, P. Käser, J. Cerdà, A. Hierlemann, H. Baltes, "Smart single-chip CMOS microhotplate aray for metal-oxide-based gas sensors", Proceedings IEEE Transducers, Boston, MA, USA, (2003), 123-126, ISBN: 0-7803-7731-1 (DOI: 10.1109/SENSOR.2003.1215268). external page Online

C. Vancura, M. Rüegg, Y. Li, D. Lange, C. Hagleitner, O. Brand, A. Hierlemann, H. Baltes, "Magnetically actuated CMOS resonant cantilever gas sensor for volatile organic compounds", Proceedings IEEE Transducers, Boston, MA, USA, (2003), 1355-1358, ISBN: 0-7803-7731-1 (DOI: 10.1109/SENSOR.2003.1217025). external page Online

P. Kurzwaski, I. Lazic, C. Hagleitner, A. Hierlemann, H. Baltes, "Multitransducer recordings from a single-chip gas sensor system coated with different polymers", Proceedings IEEE Transducers, Boston, MA, USA, (2003), 1359-1362, ISBN: 0-7803-7731-1 (DOI: 10.1109/SENSOR.2003.1217026). external page Online

M. Graf, S. Taschini, P. Käser, C. Hagleitner, A. Hierlemann, H. Baltes, "Integrated metal-oxide microsensor array of micro-hotplates with MOS-transistor heater", Proceedings Eurosensors, Guimaraes, Portugal (2003) 661-662, ISBN: 972-98603-1-9. external page Online

F. Greve, J. Lichtenberg, H. Hall, A. Hierlemann, H. Baltes, "Physical neuron immobilization by mild suction on electrode arrays", “SmallTalk”, San Jose, USA, July 13-16 (2003).

D. Barrettino, W.H. Song, M. Graf, A. Hierlemann, H. Baltes, "A micro-hotplate-based monolithic CMOS thermal analysis system", Proceedings ESSCIRC, 2003, Estoril, Portugal, editors: Jose Franca, Rudolf Koch, p. 329-332, ISBN: 0-7803-7995-0 (DOI: 10.1109/ESSCIRC.2003.1257139). external page Online

F. Heer, S. Hafizovic, W. Franks, A. Blau, C. Ziegler, S. Taschini, A. Hierlemann, H. Baltes, "CMOS neurochip for stimulation and recording of electrogenic cells", Proceedings Biosurf V” Functional Polymeric Surfaces in Biotechnology”, Sept. 25th –26th, 2003, Zurich, CH, p.103. external page Online

I. Schenker, W. Franks, P. Schmutz, A. Hierlemann, H. Baltes, "Impedance of electrodes for stimulation and recording of natural neural networks", Proceedings Biosurf V” Functional Polymeric Surfaces in Biotechnology”, Sept. 25th –26th, 2003, Zurich, CH, p. 114. external page Online

F. Greve, A. Hierlemann, H. Baltes, H. Hall, "Neuron guidance on bio-electronic chips", Proceedings Biosurf V” Functional Polymeric Surfaces in Biotechnology”, Sept. 25th –26th, 2003, Zurich, CH, p. 99. external page Online

F. Greve, J. Lichtenberg, A. Hierlemann, H. Baltes, "Physical immobilization and polymeric microchannel networks to achieve defined neuronal network structures", Miniaturized Systems for Chemistry and Life Sciences (µTas), Squaw Valley, USA, (2003), 327-330, ISBN: 0-9743611-0-0. external page Online

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2002

C. Hagleitner, D. Lange, N. Kerness, A. Hierlemann, O. Brand, H. Baltes, "A gas detection system on a single CMOS chip comprising capacitive, calorimetric, and mass-sensitive sensors", Proceedings IEEE-ISSCC, San Francisco, USA, 2002, Vol. 45, 430-431, ISBN: 0-7803-7335-9 (DOI: 10.1109/JSSC.2002.804359). external page Online

C. Hagleitner, D. Lange, N. Kerness, A. Kummer, W.H. Song, A. Hierlemann, O. Brand, H. Baltes, "CMOS single-chip multisensor gas detection system", Technical Digest IEEE-MEMS, Las Vegas, USA, 2002, 244-247, ISBN 0-7803-7185-2 (DOI: 10.1109/MEMSYS.2002.984248). external page Online

Invited: H. Baltes, O. Brand, A. Hierlemann, D. Lange, C. Hagleitner, "CMOS-MEMS, Presence and Future", Technical Digest IEEE-MEMS, Las Vegas, USA, 2002, 459-466, ISBN: 0-7803-7185-2 (DOI: 10.1109/MEMSYS.2002.984302). external page Online

A. Kummer, T. Burg, A. Hierlemann, H. Baltes, "Tuning Sensitivity and Selectivity of Monolithic CMOS Capacitive Chemical Microsensors", Proceedings 9th International Meeting on Chemical Sensors (IMCS), Boston, MA, 2002, 226-227.

M.Graf, D. Barrettino, M. Zimmermann, A. Hierlemann, H. Baltes, "CMOS Single-chip Metal Oxide Gas Sensing System Based on Microhotplates", Proceedings 9th International Meeting on Chemical Sensors (IMCS), Boston, MA, 2002, 141-142.

C. Vancura, C. Hagleitner, A. Hierlemann, O. Brand, D. Lange, H. Baltes, "Quantitative Detection of Volatile Organic Compounds Using a Single-chip CMOS Cantilever Gas Sensor Array", Proceedings 9th International Meeting on Chemical Sensors (IMCS), Boston, MA, 2002, 272-273.

D. Barrettino, M. Graf, M. Zimmermann, A. Hierlemann, H. Baltes, "A Smart Single-chip Microhotplate-based Chemical Sensor System in CMOS Technology", Proceedings 2002-IEEE-International-Symposium-on-Circuits-and-Systems, ISCAS, Phoenix, AZ, Vol. 2, 157-160. Proceedings-Cat.-No. 02CH37353 (DOI: 10.1109/ISCAS.2002.1010948). external page Online

D. Barrettino, M. Graf, M. Zimmermann, A. Hierlemann, H. Baltes, S. Hahn, N. Barsan, U. Weimar, "A System Architecture of Microhotplate-based Chemical Sensors in CMOS Technology", Proceedings Eurosensors 16, Prague, Czechia, Editors J. Sanisteir, P. Ripka, 2002, Vol. 1, 227-228, ISBN: 80-01-02576-4.

M.Graf, D. Barrettino, M. Zimmermann, A. Hierlemann, H. Baltes, "CMOS Microhotplate with MOS Transistor Heater for Integrated Metal-Oxide Microsensors", Proceedings Eurosensors 16, Prague, Czechia, Editors J. Sanisteir, P. Ripka, 2002, Vol. 2, 249-250, ISBN: 80-01-02576-4.

A. Kummer, A. Hierlemann, H. Baltes, "Tuning Selectivity of CMOS Capacitive Chemicall Microsensors", Proceedings Eurosensors 16, Prague, Czechia, Editors J. Sanisteir, P. Ripka, 2002, Vol. 3, 527-528, ISBN: 80-01-02576-4.

Invited: C. Hagleitner, A. Hierlemann, H. Baltes, "Single-chip CMOS Capacitive Gas Sensor For Detection of Volatile Organic Compounds", Proceedings of IEEE Sensors, 2002, First IEEE International Conference on Sensors, Orlando, FL, 2002, 1428-1431, Cat.-No.02CH37394 (DOI: 10.1109/ICSENS.2002.1037331). external page Online

W.H. Song, C. Hagleitner, A. Hierlemann, O. Brand, H. Baltes, "Multi Flip-chip Module for Chemical Microsystems", Proceedings 4th IEEE International Workshop on Area Array Packaging Technologies, Berlin, Germany, 2002, 4.5.1-5.

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2001

C. Hagleitner, D. Lange, O. Brand, A. Hierlemann, H. Baltes, "A single chip CMOS resonant beam gas sensor", Proceedings IEEE-ISSCC, San Francisco, USA, 2001, Vol. 44, 246-247, ISBN: 0-7803-6608-5 (DOI: 10.1109/ISSCC.2001.912623). external page Online

W. Franks, D. Lange, S. Lee, A. Hierlemann, N. D. Spencer, H. Baltes, "Nanochemical surface analyzer in CMOS technology", Conference on Sensors and Nanostructures, Makuhari, Chiba, Japan, May 2001. external page Online

2000

N. Kerness, A. Koll, A. Schaufelbühl, C. Hagleitner, A. Hierlemann, O. Brand, H. Baltes, "N-well-Based CMOS Calorimetric Chemical Sensors", Technical Digest IEEE MEMS, Miyazaki, Japan, 2000, 96-101, ISBN: 0-7803-5273-4 (DOI: 10.1109/MEMSYS.2000.838497). external page Online

N. Kerness, C. Hagleitner, A. Koll, A. Hierlemann, O. Brand, H. Baltes, "CMOS Calorimetric Chemical Gas Sensors", Abstract Book, 8th International Meeting on Chemical Sensors, Basel, 2000, 201.

D. Lange, C. Hagleitner, A. Hierlemann, O. Brand, H. Baltes, "Discrimination of Volatile Organic Compounds Using CMOS Resonant Beam Gas Sensors", Abstract Book, 8th International Meeting on Chemical Sensors, Basel, 2000, 202.

A. Krauss, D. Lange, U. Weimar, A. Hierlemann, O. Brand, H. Baltes, "Reverse Mode of Operation for Miniaturized Gas Sensor Systems", Abstracts International Symposium on Electronic Noses (ISOEN), Brighton, UK, 2000, 35-36.

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Before 2000

H. Baltes, O. Brand, C. Hagleitner, A. Hierlemann, N. Kerness, A. Koll, D. Lange, R. Vogt, "CMOS Integrated Chemical Sensors for Application-specific Micronoses", Proceedings of the 6th International Symposium Olfaction and Electronic Nose, Tübingen, Germany, M. Frank, U. Weimar, Editors, p. 95-98, 1999, ISBN: 3-00-004819-7.

A. Hierlemann, A. Koll, D.Lange, C. Hagleitner, N. Kerness, O. Brand, H. Baltes, "CMOS Based Chemical Microsensors: Components of a Micronose System", in Chemical Microsensors and Applications II, Stephanus Büttgenbach, Editor, Proc. Meeting of the SPIE, Boston, MA, Vol. 3857, 158-169, 1999, ISSN: 0277-786X, ISBN: 0-8194-3450-7 (DOI: 10.1117/12.370283). external page Online

A. Krauss, A. Koll, D. Lange, U. Weimar, A. Hierlemann, O. Brand, H. Baltes, W. Göpel, "Miniaturisierung eines Gassensorsystems für mehr Sicherheit am Arbeitsplatz", oral presentation at the 4th Dresdner Sensor-Symposium, Dresden, Germany, December 6-8, 1999.

A. Hierlemann, A.J. Ricco, K. Bodenhöfer., W. Göpel, "Molecular Recognition in Gas Sensing: Results from Acoustic Wave and In-Situ FTIR Measurements", Conf. Proc. Solid-State Sensor and Actuator Workshop, Hilton Head Island, USA, 1998, Late News Contributions, p. 41, ISBN: 09640024-2-6.

W.M. Lackowski, J.K. Campbell, G. Edwards, L.A. Baker, R.M. Crooks, A. Hierlemann, A.J. Ricco, "Structural Characterization of Dendrimer/n-Alkanethiol Mixed Monolayers on Au (111)", Materials Research Society Fall Meeting, Boston, USA, 1998.

A. Hierlemann, A.J. Ricco, K. Bodenhöfer., W. Göpel, "Acoustic Wave and In-Situ FTIR Characterization of Molecular Recognition in Gas Sensors", Meeting of the Electrochem. Soc., Boston, USA, 1998, Meeting Abstracts Vol. 98-2, Abstr. 1219, ISSN: 1091-8213.

W. Göpel, K. Bodenhöfer., A. Hierlemann, V. Schurig, "Artificial Noses and Chiral Discrimination: Mass-sensitive Chemical Sensors and Chromatographic Columns with Biomimetic Coatings", Meeting of the Electrochem. Soc. Proc., Vol. 97-19 (1997) 1053-1057, ISBN: 1-56677-147-1. external page Online

K. Bodenhöfer, A. Hierlemann, W. Göpel, M. Juza, B. Gross and V. Schurig, "Efficient Gas Sensor Mediated Enantiomer Discrimination of 2-Substituted Methyl Propionates and Chiral Inhalation Anaesthetics on a Modified Cyclodextrin", Conf. Proc. Chiral Europe, London, England 1997,  ISSN: 0392-839X. external page Online

K. Bodenhöfer, A. Hierlemann, W. Göpel, "Chiral Recognition by Simple Gas Sensors", Conf. Proc. International Conference on Solid State Sensors and Actuators, Chicago, USA, 1997, IEEE Catalog 6/1997, 1391-1394, ISBN: 0-7803-3829-4/97.

W. Göpel, K. Bodenhöfer., A. Hierlemann, V. Schurig, "Artificial Noses and Chiral Discrimination: The Use of Biomimetic Coatings for Mass-sensitive Chemical Sensors and for Chromatographic Columns", Conf. Proc. Eurosensors XI, Warsaw (P), 1997. external page Online

J. Mitrovics, A. Hierlemann, F. Davide, A. Lloyd Spetz, T. Ringvall, G. Hamrefors, D. Sauter, P. Martensson, C. DiNatale, U. Weimar, A. D'Amico, I. Lundström, L. Ludwig, J. Göppert, W. Rosenstiel, W. Göpel, "Dynamic Analysis of Process Gases in a PFBC Plant with a Hybrid Sensor Array", Conf. Proc. 6th International Meeting on Chemical Sensors, NIST, Gaithersburg, USA 1996 (DOI: 0.6028/jres.102.009). external page Online

G. Kraus, A. Hierlemann, W. Göpel, G. Gauglitz, "Application of Artificial Neural Networks in Chemical Sensing: Analysis of Hydrocarbon Vapours with Optical and Mass Sensitive Transducers", Conf. Proc. 9. CIS-Workshop: Softwareentwicklung in der Chemie, Jahrestagung GDCh, Bitterfeld 11/1995.

R. Zhou, A. Hierlemann, U. Weimar, W. Göpel, Gravimetric, "Dielectric and Calorimetric Methods for the Detection of Organic Solvent Vapours Using Polyetherurethane Coatings", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 450-PD9, Vol. I, 886-889, ISBN: 91-630-3473-5 (DOI: 10.1016/S0925-4005(96)01912-0). external page Online

R. Zhou, A. Hierlemann, U. Weimar, D. Schmeisser, W. Göpel, "Mass-Sensitive Detection of CO2 by Amino-group Functionalized Polymers", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 225-PD6, Vol. II, 833-836, ISBN: 91-630-3473-5 (DOI:10.1016/0925-4005(96)80096-7). external page Online

M. Schweizer, A. Hierlemann, K. Bodenhöfer, J. Mitrovics, U. Weimar, W. Göpel, "Evaluation of Dynamic Sensor Signals by Artificial Neural Nets", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 171-D1, Vol. I, 679-682, ISBN: 91-630-3473-5 (DOI: 10.1109/SENSOR.1995.717322). external page Online

G. Kraus, A. Hierlemann, G. Gauglitz, W. Göpel, "Analysis of Complex Gas Mixtures by Pattern Recognition with Polymer-Based QMB-Sensor Arrays", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 170-D1, Vol. I, 675-678, ISBN: 91-630-3473-5 (DOI: 10.1109/SENSOR.1995.721696). external page Online

F.P. Steiner, A. Hierlemann, C. Cornila, G. Noetzel, M. Bächtold, J: Korvink, W. Göpel, H. Baltes, "Polymer Coated Capacitive Microintegrated Gas Sensors", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 445-D9, Vol. II, 814-817, ISBN: 91-630-3473-5 (DOI: 10.1109/SENSOR.1995.721696). external page Online

S. Marco, A. Pardo, F. Davide, C. DiNatale, A. D'Amico, A. Hierlemann, W. Göpel, "Different Strategies for the Dynamic Calibration of Gas Sensors", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 242-PA7, Vol.II, 44-47, ISBN: 91-630-3473-5 (DOI: 10.1109/SENSOR.1995.721696). external page Online

A. Hierlemann, K. Bodenhöfer, M. Fluck, V. Schurig, W. Göpel, "Selective Detection of Nitrogen- and Oxygen-Containing Analytes Using Metal-Modified Polysiloxanes", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 427-PD7, Vol. II, 751-754, ISBN: 91-630-3473-5 (DOI: 10.1109/SENSOR.1995.721696). external page Online

A. Hierlemann, K. Bodenhöfer, G. Noetzel, U. Weimar, W. Göpel, "Comparison of Mass-Sensitive Devices for Gas Sensing", Conf. Proc. 8th International Conference on Solid State Sensors and Actuators, Stockholm, Sweden (1995) 421-D7, Vol. II, 728-731, ISBN: 91-630-3473-5 (DOI: 10.1109/SENSOR.1995.721696). external page Online

A. Hierlemann, W. Göpel, "Sensorsysteme und Mustererkennung: Einsatz zur Kohlenwasserstoffanalytik", Conf. Proc. INCOM, Düsseldorf 1994, 225.177.

A. Hierlemann, M. Schweizer-Berberich, U. Weimar, W. Göpel, Conf. Proc. Analytica, München 1994, 173-178.

K.D. Schierbaum, A. Hierlemann, R. Zhou, W. Göpel, "Model Systems of Polymeric and Supramolecular Layers for Chemical Sensors", Conf. Proc. 7th International Symposium on Synthetic Membranes in Science and Industry, Tübingen 1994, 434 ff.

R. Zhou, A. Hierlemann, K.D. Schierbaum, K.E. Geckeler, W. Göpel, "Detection of Organic Solvents with Reliable Chemical Sensors Based on Cellulose Derivatives", Conf. Proc. 5th Int. Meeting on Chemical Sensors, Rome Italy (7/1994), 563-566 (DOI: 10.1016/0925-4005(95)85099-6). external page Online

C. DiNatale, F. Davide, A. D'Amico, A. Hierlemann, J. Mitrovics, M. Schweizer, U. Weimar, W. Göpel, "A composed neural net for the recognition of gas mixtures", Conf. Proc. 5th Int. Meeting on Chemical Sensors, Rome, Italy (7/1994), 1101-1104 (DOI: 10.1016/0925-4005(95)85180-1). external page Online

C. Cornila, A. Hierlemann, R. Lenggenhager, P. Malcovati, H. Baltes, G. Noetzel, U. Weimar, W. Göpel, "Capacitive Sensors in CMOS Technology with Polymer Coating", Conf. Proc. 5th Int. Meeting on Chemical Sensors, Rome, Italy, (7/1994), 450-453 (DOI: 10.1016/0925-4005(95)85080-5). external page Online

F.A.M. Davide, C. DiNatale, A. D'Amico, A. Hierlemann, J. Mitrovics, M. Schweizer, U. Weimar, W. Göpel, S. Marco, A. Pardo, "Dynamic Calibration of QMB Polymer-Coated Sensors by Wiener Kernel Estimation", Conf. Proc. 5th Int. Meeting on Chemical Sensors, Rome, Italy (7/1994), 1101-1104 (DOI: 10.1016/0925-4005(94)01601-D). external page Online

F.A.M. Davide, C. DiNatale, A. D'Amico, A. Hierlemann, J. Mitrovics, M. Schweizer, U. Weimar, W. Göpel, "Structure Identification of Nonlinear Models for QMB Polymer-Coated Sensors", Conf. Proc. Eurosensors VIII, Toulouse (F) (9/1994) (DOI: 10.1016/0925-4005(95)85185-2). external page Online

J.W. Gardner, A. Pike, N. F. de Rooij, M. Koudelka-Hep, P. Clerc, A. Hierlemann, W. Göpel, "Integrated Array Sensor for Detecting Organic Solvents", Conf. Proc. Eurosensors VIII, Toulouse (F) (9/1994) (DOI: 10.1016/0925-4005(94)01573-Z). external page Online

M. Schweizer, J. Göppert, A. Hierlemann, J. Mitrovics, U. Weimar, W. Rosenstiel, W. Göpel, "Application of Neural Network Systems to the Dynamic Response of Polymer-Based Sensor Arrays", Conf. Proc. Eurosensors VIII, Toulouse (F) (9/1994) (DOI: 10.1016/0925-4005(94)01592-6). external page Online

A. Hierlemann, U. Weimar, G. Kraus, M. Schweizer, W. Göpel, "Polymer-Based Sensor Arrays and Multicomponent Analysis for the Detection of Hazardous Organic Vapours in the Environment", Conf. Proc. Eurosensors VIII, Toulouse (F) (9/1994).

H.-D. Wiemhöfer, U. Vohrer, Th. Lang, S. Brosda, A. Dubbe, J. Fleig, A. Hierlemann, H. Keller, and W. Göpel, "CO2-Gassensoren: Grenzflächencharakterisierung und Sensortests", Conf. Proc. Sensor 93, 6, Nürnberg (FRG) (1993) 73.

K.D. Schierbaum, A. Hierlemann, W.Göpel, "Modified Polymers for Reliable Detection of Organic Solvents", Conf. Proc. Eurosensors VII, Budapest, Hungary, 9/1993 (DOI: 10.1016/0925-4005(93)01034-2). external page Online