icbn

Isotonic regression Conjunctive Bayesian Network models

Current version

0.2-13 Aug 2010

Description

The R package icbn implements algorithms for parameter estimation and model selection for Isotonic Conjunctive Bayesian Network (I-CBN) models. I-CBNs combine isotonic regression on a partially ordered set with CBNs for estimating order constraints among events. The model has been developed to jointly estimate mutational order constraints among genetic events and a genotype-phenotype mapping (such as a fitness landscape) that is non-decreasing along the lattice of genotypes.

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icbn is distributed under the external page GNU General Public License.

Authors and Contributors

Niko Beerenwinkel

external page Patrick Knupfer

external page Achim Tresch

Citation