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Our Research Group

We research in the areas of computational biology, biostatistics, and systems biology. Our activities include the development of mathematical and statistical models, their implementation in computer programs, and application to biomedical problems. We have active research projects on HIV drug resistance, the somatic evolution of cancer, haplotype inference from ultra-deep sequencing data, and reconstruction of signaling pathways from RNAi screens.

Surveillance of SARS-CoV-2 genomic variants in wastewater

We have developed several computational tools and integrated them into external page V-Pipe for analyzing viral sequencing data obtained from wastewater samples. In a program commissioned by the Swiss Federal Office of Public Health, we use these methods to monitor SARS-CoV-2 genomic variants in Swiss wastewater treatment plans. The latest results can be found external page here.

CBG News

Release of V-pipe 3.0

Assessing different next-generation sequencing technologies for wastewater-based epidemiology

The role of bioinformatics in genomic reproducibility

Google Season of Docs

ISCB Fellow

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