Congratulations to PhD student Simona Baghai Sain on her Nature co-first

PhD student Simona Baghai Sain has achieved a remarkable milestone as a co-first author in a pivotal study published in Nature. In collaboration with Ataman Sendoel's team from the Institute for Regenerative Medicine at the University of Zurich (UZH), Simona helped elucidating the role of TNF-alpha in driving clonal expansions and tumorigenesis in the skin. Her contribution focused on analyzing the spatial composition of growing tumors and assessing an invasion-driving tumor cell subset thriving on an autocrine TNF-alpha loop. Congratulations to Simona and all the other contributing authors for this significant achievement!

Read more about this fascinating project in the D-BSSE News and external page UZH News. The full publication can be found here: Renz, P. F., Ghoshdastider, U., Baghai Sain, S., and colleagues (2024) In vivo single-cell CRISPR uncovers distinct TNF-α programs in clonal expansion and tumorigenesis. Nature. 17 July 2024: DOI: external page https://doi.org/10.1038/s41586-024-07663-y.