Dr. Tania Roberts
Dr. Tania Roberts
Staff of Professorship for Bioprocess
Research
My research involves fine-tuning the yeast Saccharomyces cerevisiae to produce vitamins of interest and as such I have developed a YFP-based sensor strain and an HPLC-based method for product characterization.
I also develop protocols that enable yeast to act as a better tool for pathway engineering of yeast or bacteria and have been involved in various projects that use flow cytometry to screen for desired novel properties of fluorescent proteins.
Finally, I aid in the design and development of many of the projects in the Bioprocess Laboratory.
Curriculum Vitae
Work Experience
Education
Publications
external pageStandardization of Synthetic Biology Tools and Assembly Methods for Saccharomyces cerevisiae and Emerging Yeast Species. K. Malcı et al. ACS Synthetic Biology (2022)
external pagePlasmid replication based on the T7 origin of replication requires a T7 RNAP variant and inactivation of ribonuclease H. K. Becker, A. Meyer, T.M. Roberts, S. Panke. Nucleic Acids Research (2021).
external pageUltra-high throughput screening for novel protease specificities. E. Rousounelou, S. Schmitt, L. Pestalozzi, M. Held, T.M. Roberts & S. Panke. Methods in Enzymology (2020).
external pageDevelopment and Optimisation of a Defined High Cell Density Yeast Medium. T.M. Roberts, H.-M.Kaltenbach & F. Rudolf. Yeast (2020).
external pageSequence-based prediction of permissive stretches for internal protein tagging and knockdown. S. Oesterle, T. M. Roberts, L. A. Widmer, H. Mustafa, S. Panke & S. Billerbeck. BMC Biology (2017).
external pageEfficient engineering of chromosomal ribosome binding site libraries in mismatch repair proficientEscherichia coli. S. Oesterle, D. Gerngross, Steven Schmitt, T.M. Roberts & S. Panke. Scientific Reports (2017).
external pageIdentification and Characterisation of a pH-stable GFP. T.M. Roberts, F. Rudolf, A. Meyer, R. Pellaux, E. Whitehead, S. Panke & M. Held. Scientific Reports (2016).
external pageSynthetic Biology for Cell-Free Biosynthesis: Fundamentals of Designing Novel In Vitro Multi-Enzyme Reaction Networks. G. Morgado, D. Gerngross, T.M. Roberts & S. Panke. Advances in Biochemical Engineering/Biotechnology (2016).
external pageFunctional targeting of DNA damage to a nuclear pore associated SUMO-dependent ubiquitin ligase. S. Nagai, K. Dubrana, M. Tsai-Pflugfelder, M.B. Davidson, T.M. Roberts, G.W. Brown, E. Varela, F. Hediger, S.M. Gasser & N.J. Krogan. Science (2008).
external pageRegulation of Rtt107 Recruitment to Stalled DNA Replication Forks by the Cullin Rtt101 and the Rtt109 Acetyltransferase. T.M. Roberts, I.W. Zaidi, J.A. Vaisica, M. Peter & G.W. Brown. Molecular Biology of the Cell (2008).
external pageSlx4 Regulates DNA Damage-Dependent Checkpoint Phosphorylation of the BRCT-Containing Protein Rtt107. T.M. Roberts, M.S. Kobor, S.A. Bastin-Shanower, M. Ii, S.A. Horte, J.W. Gin, A. Emili, J. Rine, S.J. Brill & G.W. Brown. Molecular biology of the cell (2006).
external pageSuppression of Genomic Instability by SLX5 and SLX8 in Saccharomyces cerevisiae. C. Zhang, T.M. Roberts, J. Yang, R. Desai & G.W. Brown. DNA Repair (2005).
external pageGlobal Mapping of the Yeast Genetic Interaction Network. A.H.Y. Tong et al. Science (2004).
external pageA Re-evaluation of the Role of Histidine 426 Within Pseudomonas aeruginosa Exotoxin A. T.M. Roberts & A.R Merrill. Biochemical Journall (2002).