In Silico Organogenesis
We use image-based modeling to generate 4D models of organogenesis. Here, we focus in particular on lung, kidney, and CNS development.
Lung, Kidney & Pancreas Development
How are reliable symmetry breaks achieved during branching morphogenesis? And how are developmental processes coordinated such that functional units emerge, i.e. the branching of the ureteric tree with the formation of nephrons to achieve efficient drainage? What are the relative contributions of chemical signalling and tissue mechanics?
