Cell & Organoid System

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Our cell and organoid culture automation lab specializes in mammalian cell cultivation, including organoid and tissue cultures. Utilizing state-of-the-art robotic systems, we automate essential processes such as routine maintenance, continuous monitoring, and precise manipulation of cultures over an extended period of time. This advanced automation streamlines workflows, ensures consistent and reproducible results, and reduces the risk of human error and contamination.

We have enclosed the whole automation system in a BSL-2 Compliant housing enabling it to handle BSL-2 samples and workflows.

Enlarged view: Cellario Scheduler

In modern biological research, coordinating multiple automated devices is essential for efficient and accurate experimental workflows. Scheduling software, such as HighRes Biosolutions' CellarioScheduler, which we use in this lab, facilitates this integration by enabling scientists to design, execute, and monitor complex protocols across various laboratory instruments. These platforms allow for the seamless orchestration of tasks among devices like liquid handlers, plate readers, and incubators, ensuring synchronized operations and optimal resource utilization. This capability allows multiple users to run their workflows in parallel, interleaving tasks as needed. By employing such scheduling solutions, you can enhance throughput, maintain consistency, and reduce manual intervention, ultimately accelerating your research. 

Workflows

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Integrated Devices

  • Liquid Handling Robots
    • Hamilton Microlab STAR
    • Hamilton Microlab STAR Plus
  • Incubators 
    • 2x HighRes SteriStore 
  • Plate Measurement Modes 
    • High Content Imager – Yokogawa Cell Voyager CQ3000 
    • Plate reading and imaging – Tecan Spark Cyto
    • Flow cytometry – Beckman Coulter CytoFlex S 
  • Plate Sealing and Peeling 
    • Agilent PlateLoc 
    • Azenta Automated Plate Seal Remover
  • Integration Robot
    • Brooks PreciseFlex 400 Arm and Rail – ACell system powered by HighRes Biosolutions
  • Plate washing and dispensing
    • BlueCatBio BlueWasher XL

Contact LAF for services, location, and information requests

Department of Biosystems Science and Engineering