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Biophysics Group

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The Biophysics Group

The Biophysics Group develops and applies nanotechnological imaging and manipulation tools to characterize cellular membranes and membrane proteins in vitro and in vivo, to address pertinent problems in cell biology and to engineer molecular systems.

News

Dr. Carson Cole awarded the ETH Postdoctoral Fellowship

Carson Cole, Ph.D., has been awarded the ETH Zürich Postdoctoral Fellowship. He joins Prof. Dr. Daniel J. Müller’s Biophysics group at D-BSSE to develop biomimetic peptide fibrils to study fibrosis. His work aims to understand fibrotic tissue remodeling and enables innovative in vitro models for therapeutic testing. This prestigious fellowship supports independent, high-impact research for postdoctoral scholars seeking faculty positions.

New publication from Krishna in Nature Nanotechnology

In his latest publication, Krishna characterized how cortical neurons sense and respond to various mechanical stimuli. The cover image of Krishna’s work depicts a colored scanning electron microscopy (SEM) image of a network of cortical neurons grown on a microelectrode array used for combined force and electrophysiological measurements.

In mitosis integrins reduce adhesion to extracellular matrix and strengthen adhesion to adjacent cells

How cells modulate their adhesion to the extracellular matrix (ECM) and to neighboring cells during mitotic cell rounding remained elusive. We recently deciphered that cell-ECM adhesion components are released prior to mitosis and are rewired to synergize with cadherins to strengthen adhesion to adjacent cells.

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