On 1 September 2026, Dr Kasper Spoelstra joined the Müller group as a postdoctoral researcher.
Kasper completed his PhD at AMOLF Amsterdam & TU Delft, where he used
organoid models and quantitative imaging to study the dynamics of the
intestinal epithelium.
We are delighted to have Kasper with us. Welcome to the group, Kasper!
Today, we gathered for Xiaole’s farewell breakfast and enjoyed a delicious selection of Chinese dishes. It was great to spend time together and celebrate her achievements and the time she has shared with our group.
Thank you, Xiaole, for your contributions to the Müller group. We will miss you and wish you lots of happiness and success in your next chapter.
How do membrane lipids regulate GPCR signalling? A new study in Nature Structural & Molecular Biology combines single-molecule force spectroscopy with molecular dynamics simulations. It was led by co-first authors Florian, on whose PhD work in our group this study builds, and Kristyna, a former postdoc in our group. The work reveals how β-arrestin2 engages the β2-adrenergic receptor in distinct steps and identifies PIP2 as a key regulator of complex assembly and stability.
A new Perspective in Nature Nanotechnology, co-authored by Krishna Chaitanya Kasuba, Upnishad Sharma, Valentin Gensbittel and Michele M. Nava from our group, presents a roadmap for advancing mechanobiology across molecular, cellular and tissue scales. It calls for multiscale measurement tools, realistic biological models, integrated datasets and predictive frameworks to deepen our understanding of complex living systems and advance mechanodiagnostics and mechanomedicine.
From May 4–7, 2026, we gathered in Orta San Giulio, Italy, for our lab retreat. The retreat provided a valuable opportunity to share project updates, discuss new ideas, and strengthen collaborations within the lab. We were delighted to welcome Reinhard Fässler, Gregory Giannone, Sebastian Hiller, and Nico Strohmeyer, whose contributions enriched the scientific program. Together with the inspiring setting by Lake Orta, the retreat was both productive and enjoyable.