2020
Within-patient genetic diversity of SARS-CoV-2
Our analysis on public and Swiss datasets of intra-host genetic diversity of SARS-CoV-2 is now available.
D-BSSE eSymposium 13 Oct. 2020
What do SARS-CoV-2 genomes tell us about their evolution and spread? Niko Beerenwinkel and Jack Kuipers are presenting ongoing efforts of our group on SARS-CoV-2 genomic heterogeneity.
V-pipe for analyzing SARS-CoV-2 sequencing data
We have released a new version of V-pipe, our bioinformatics pipeline for viral NGS data. The updated release is specifically adapted to analyse high-throughput sequencing data of SARS-CoV-2. It also integrates a new version of ShoRAH for SNV calling, and it supports reporting genetic variants in standard VCF files.
Predicting colorectal cancer risk
Colorectal cancer is a major public health burden. Understanding the transition from benign polyps to malignant carcinomas can help to improve colorectal cancer screenings. Researchers from Niko Beerenwinkel’s group combined large-scale epidemiological datasets and applied new mathematical and computational modelling to estimate cancer development. The new method also provides a tool for predicting the risk of the presence of cancer cells for each screened patient.