Publications
2024 | 2023 | 2022 | 2021 | 2020 |2019 | 2018 | 2017 | 2016 | 2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2000 | 1999
Please note: PDF files available upon request: Timm Schroeder
Group members in bold.
Publications from Timm Schroeder’s groups until 2013 also shown.
2024
Rai, Zhang, Grockowiak, Kimmerlin, Hansen, Stoll, Usart, Luque Paz, Hao-Shen, Zhu, Roux, Bader, Dirnhofer, Farady, Schroeder, Méndez-Ferrer, Skoda
external pageIL-1β promotes MPN disease initiation by favoring early clonal expansion of JAK2-mutant hematopoietic stem cellscall_made
Blood Advances, Online ahead of print
Mueller*, Schimmer*, Koch, Schneiter, Fullin, Lysenko, Pellegrino, Klemm, Russkamp, Myburgh, Volta, Theocharides, Kurppa, Ebert, Schroeder, Manz*, Boettcher*
external pageTargeting the mevalonate or Wnt pathways to overcome CAR T-cell resistance in TP53-mutant AML cellscall_made
EMBO Molecular Medicine, Online ahead of print
Kockwelp*, Thiele*, Bartsch*, Haalck, Gromoll, Schlatt, Exeler, Bleckmann, Lenz, Wolf, Steffen, Berdel, Schliemann, Risse, Angenendt
external pageDeep Learning Predicts Therapy-Relevant Genetics in Acute Myeloid Leukemia from Pappenheim-stained Bone Marrow Smearscall_made
Blood Advances, 8(1):70-79
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2023
Arekatla, Trenzinger, Reimann, Loeffler, Kull, Schroeder
external pageOptogenetic manipulation identifies the roles of ERK and AKT dynamics in controlling mouse embryonic stem cell exit from pluripotencycall_made
Developmental Cell, 58(12):1022-1036
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Reimann*, Kull*, Wang, Dettinger, Loeffler, Schroeder
external pageEmbryonic stem cell ERK, AKT plus STAT3 response dynamics combinatorics are heterogeneous but NANOG state independentcall_made
Stem Cell Reports, 18(6):1295-1307
Stetka, Usart, Kubovcakova, Rai, Rao, Sutter, Hao-Shen, Dirnhofer, Geier, Bader, Passweg, Manolova, Dürrenberger, Ahmed, Schroeder, Ganz, Nemeth, Silvestri, Nai, Camaschella, Skoda
external pageIron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasmscall_made
Blood, 141(17):2127-2140
Barz*, Behrmann*, Capron*, Zuchtriegel*, Steffen, Kunz, Zhang, Jimenez Vermeerbergen, Marovca, Kirschmann, Rinaldi, Zech, Nombela-Arrieta, Ziegler, Schroeder, Bornhauser, Bourquin
external pageB and T cell acute lymphoblastic leukemia evade chemotherapy at distinct sites in the bone marrowcall_made
Haematologica, 108(5):1244-1258
Angenendt, Röllig, Montesinos, Ravandi, Juliusson, Récher, Itzykson, Ráčil, Wei, Schliemann
external pageRevisiting Co-existing Chromosomal Abnormalities in NPM1-mutated AML in Light of the Revised ELN 2022 classificationcall_made
Blood, 141(4):433-435
Gräbnitz, Stark, Shlesinger, Petkidis, Borsa, Yermanos, Carr, Barandun, Wehling, Balaz, Schroeder, Oxenius
external pageAsymmetric cell division safeguards memory CD8 T cell developmentcall_made
Cell Reports, 42(5):112468
Vinopal, Dupraz, Alfadil, Pietralla, Bendre, Stiess, Falk , Camargo Ortega, Maghelli , Tolić, Smejkal, Götz, Bradke
external pageCentrosomal microtubule nucleation regulates radial migration of projection neurons independently of polarization in the developing braincall_made
Neuron, 111(8):1241-1263
Beneyto-Calabuig, Merbach, Kniffka, Antes, Szu-Tu, Rohde, Waclawiczek, Stelmach, Gräßle, Pervan, Janssen, Landry, Benes, Jauch, Brough, Bauer, Besenbeck, Felden, Bäumer, Hundemer, Sauer, Pabst, Wickenhauser, Angenendt, Schliemann, Trumpp, Haas, Scherer, Raffel, Müller-Tidow, Velten
external pageClonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemiacall_made
Cell Stem Cell, 30(5):706-721
2022
Wehling, Loeffler, Zhang, Kull, Donato, Szczerba, Camargo Ortega, Lee, Moor, Goettgens, Aceto, Schroeder
external pageCombining single-cell tracking and omics improves blood stem cell fate regulator identificationcall_made
Blood, 140(13):1482-1495
Loeffler*, Schneiter*, Wang, Wehling, Kull, Lengerke, Manz, Schroeder
external pageAsymmetric organelle inheritance predicts human blood stem cell fatecall_made
Blood, 139(13):2011-2023
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Kull, Wehling, Etzrodt, Auler, Dettinger, Aceto, Schroeder
external pageNfκB signaling dynamics and their target genes differ between mouse blood cell types and induce distinct cell behaviorcall_made
Blood, 140(2):99-111
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Ahmed, Etzrodt, Dettinger, Kull, Loeffler, Hoppe, Chavez, Zhang, Ortega, Hilsenbeck, Nakajima, Pietras, Schroeder
external pageBlood stem cell PU.1 upregulation is a consequence of differentiation without fast autoregulationcall_made
Journal of Experimental Medicine, 219(1):e20202490
Dettinger**, Kull, Arekatla, Ahmed, Zhang, Schneiter, Wehling, Schirmacher, Kawamura, Loeffler, Schroeder**
external pageOpen-source personal pipetting robots with live-cell incubation and microscopy compatibilitycall_made
bioRxiv 2021; doi /10.1101/2021.07.04.448641
Nature Communications, 13(1):2999
"Editor's external pageHighlightcall_made"
Plambeck, Kazeroonian, Loeffler, Kretschmer, Salinno, Schroeder, Busch, Flossdorf, Buchholz
external pageHeritable changes in division speed accompany the diversification of single T cell fatecall_made
PNAS, 119(9):e2116260119
Scheidmann, Castro-Giner, Strittmatter, Krol, Paasinen-Sohns, Scherrer, Donato, Gkountela, Szczerba, Diamantopoulou, Muenst, Vlajnic, Kunz, Vetter, Rochlitz, Taylor, Giachino, Schroeder, Platt, Aceto
external pageAn In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progressioncall_made
Cancer Research, 82(4):681-694
Camargo, Goetz
external pageCentrosome heterogeneity in stem cells regulates cell diversitycall_made
Trends in Cell Biology, S0962-8924(22)00076-9
Angenendt, Mikesch, Schliemann
external pageEmerging antibody-based therapies for the treatment of acute myeloid leukemiacall_made
Cancer Treatment Reviews, 108:102409
Berdel, Ruhnke, Angenendt, Wermke, Röllig, Mikesch, Scheller, Hemmerle, Matasci, Wethmar, Kessler, Gerwing, Hescheler, Schäfers, Hartmann, Altvater, Rossig, Bornhäuser, Lenz, Stelljes, Rueter, Neri, Berdel, Schliemann
external pageUsing stroma-anchoring cytokines to augment ADCC: a phase 1 trial of F16IL2 and BI 836858 for posttransplant AML relapsecall_made
Blood Advances, 28;6(12):3684-3696
2021
Wang*, Zhang*, Dettinger, Reimann, Kull, Loeffler, Manz, Lengerke, Schroeder
external pageCytokine combinations for human blood stem cell expansion induce cell type- and cytokine-specific signaling dynamicscall_made
Blood, 138(10):847-857
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Kull and Schroeder
external pageAnalyzing signaling activity and function in hematopoietic cellscall_made
Journal of Experimental Medicine, 218(7):e20201546
Loeffler and Schroeder
external pageSymmetric and asymmetric activation of hematopoietic stem cellscall_made
Current Opinion in Hematology, 28(4):262-268
Chavez, Rabe, Loeffler, Higa, Hernandez, Mills, Ahmed, Gessner, Ke, Idler, Kim, Myers, Stevens, Jordan, Nakajima, Ashton, Welner, Schroeder, DeGregori, Pietras
external pagePU.1 enforces quiescence and limits hematopoietic stem cell expansion during inflammatory stresscall_made
bioRxiv (2020), 20200520
Journal of Experimental Medicine, 218(6):e20201169
García-Prat, Kaufmann, Schneiter, Voisin, Murison, Chen, Chan-Seng-Yue, Gan, McLeod, Smith, Shoong, Paris, Pan, Zeng, Krivdova, Gupta, Takayanagi, Wagenblast, Wang, Lupien, Schroeder, Xie, Dick
Dichotomous regulation of lysosomes by MYC and TFEB controls hematopoietic stem cell fate
bioRxiv, 20210224
external pageTFEB-mediated endo-lysosomal activity controls hematopoietic stem cell fatecall_made
Cell Stem Cell, 28(10):1838-1850
Hausmann, Felmy, Kunz, Kroon, Berthold, Ganz, Sandu, Nakamura, Zangger, Zhang, Dolowschiak, Fattinger, Furter, Müller-Hauser, Barthel-Scherrer, Vlantis, Wachsmuth, Kisielow, Tortola, Heide, Heikenwälder, Oxenius, Kopf, Schroeder, Pasparakis, Sellin, Hardt
external pageIntercrypt Sentinel Macrophages Induce a Tunable Antibacterial NFκB Response in Intestinal Epithelial Cells via TNFcall_made
Journal of Experimental Medicine, 218(11):e20210862
Wanet, Bassal, Lourenco, Mariani, Ahmed, Borchiellini, Chen, Zhang, Di Ruscio, Miyake, Tsai, Paranjape, Park, Silberstein, Karasuyama, Schroeder, Dzierzak, Galli, Tenen, Welner
external pageE–cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fatescall_made
Science Immunology, 6(56):eaba0178
Xie, Kaufmann, Wang, Chan-Seng-Yue, Gan, Laurenti, Garcia-Prat, Takayanagi, Ng, Xu, Zeng, Jin, McLeod, Mitchell, Kennedy, Liu, Boutzen, Kleinau, Jargstorf, Holmes, Zhang, Voisin, Bader, Wang, Hannun, Luberto, Schroeder, Minden, Dick
external pageSphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiationcall_made
Blood Cancer Discovery, 2(1):32-53
Le Mercier, Bonnavion, Yu, Wessam Alnouri, Zhang, Jäger, Cho, Chen, Strilic, Sijmonsma, Adams, Schroeder, Rieger, Offermanns
external pageGPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasiscall_made
PNAS, 118(17):e2021596118
Rao, Hansen, Stetka, Paz, Kalmer, Hilfiker, Endele, Ahmed, Kubovcakova, Rybarikova, Hao-Shen, Geier, Beisel, Dirnhofer, Schroeder, Brümmendorf, Wolf, Koschmieder, Skoda
external pageJAK2-V617F and interferon-α induce megakaryocyte-biased stem cells characterized by decreased long-term functionalitycall_made
Blood, 137(16):2139-2151
Nguyen, Misun, Lohasz, Lee, Wang, Schroeder, Hierlemann
external pageAn immunocompetent microphysiological system to simultaneously investigate effects of anti-tumor natural killer cells on tumor and cardiac microtissuescall_made
Frontiers in Immunology, 12:781337
Schaberg, Theocharidis, May, Lessmann, Schroeder, Faissner
external pageSulfation of glycosaminoglycans modulates the cell cycle of embryonic mouse spinal cord neural stem cellscall_made
Frontiers Cell and Developmental Biology, 9:643060
Ohteki, Kawamura, Onai
external pageCommitment to dendritic cells and monocytescall_made
International Immunology, dxab031
Cable, Elowitz, Domingos, Habib, Itzkovitz, Hamidzada, Balzer, Yanai, Liberali, Whited, Streets, Cai, Stergachis, Hong, Keren, Guilliams, Alon, Shalek, Hamel, Pfau, Raj, Quake, Zhang, Fan, Trapnell, Wang, Greenwald, Vento-Tormo, Santos, Spencer, Garcia, Arekatla, Gaiti, Arbel-Goren, Rulands, Junker, Klein, Morris, Murray, Galloway, Ratz, Romeike.
external pageSingle cell biology-a Keystone Symposia report.call_made
ANYAS, 1506(1):74-97
2020
Kokkaliaris KD, Kunz L, Cabezas-Wallscheid N, Christodoulou C, Renders S, Camargo F, Trumpp A, Scadden DT, Schroeder T (2020)
external pageAdult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinationscall_made
Blood 136(20): 2296–2307
Ahmed N, Kunz L, Hoppe PS, Loeffler D, Etzrodt M, Ortega GC, Hilsenbeck O, Anastassiadis K, Schroeder T (2020)
external pageA novel GATA2 protein reporter mouse reveals hematopoietic progenitor cell typescall_made
Stem Cell Reports, 15(2): 326–339
Dettinger P, Wang W, Ahmed N, Zhang Y, Löffler D, Kull K, Etzrodt M, Lengerke C, Schroeder T (2020)
external pageAn Automated Microfluidic System for Efficient Capture of Rare Cells and Rapid Flow-free Stimulationcall_made
Lab on a Chip, 10.1039/D0LC00687D
Loeffler D, Schneiter F, Schroeder T (2020)
external pagePitfalls and requirements in quantifying asymmetric mitotic segregationcall_made
ANYAS, 1466(1):73-82
Christodoulou C, Spencer JA, Turcotte R, Kokkaliaris KD, Panero R, Ramos A, Esipova TV, Vinogradov SA, Perkins AS, Schroeder T, Lin CP, Camargo FD (2020)
external pageLive-animal imaging of native hematopoietic stem and progenitor cellscall_made
Nature, 578(7794):278-283
Altamura S, Vegi NM, Hoppe PS, Schroeder T, Aichler M, Walch A, Okreglicka K, Hültner L, Schneider M, Ladinig C, Kuklik-Roos C, Mysliwietz J, Janik D, Neff F, Rathkolb B, Hrabé de Angelis M, Buske C, da Silva AR, Muedder K, Conrad M, Ganz T, Kopf M, Muckenthaler MU, Bornkamm GW (2020)
external pageGlutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasiscall_made.
Haematologica, 105(4):937-950
Donato C, Kunz L, Castro-Giner F, Paasinen-Sohns A, Strittmatter K, Szczerba BM, Scherrer R, Di Maggio N, Heusermann W, Biehlmaier O, Beisel C, Vetter M, Rochlitz C, Weber WP, Banfi A, Schroeder T, Aceto N (2020)
external pageHypoxia Triggers the Intravasation of Clustered Circulating Tumor Cellscall_made
Cell Reports, 32(10):108105
Rajendiran S, Smith-Berdan S, Kunz L, Risolino M, Selleri L, Schroeder T, Forsberg EC (2020)
external pageUbiquitous Overexpression of CXCL12 Confers Radiation Protection and Enhances Mobilization of Hematopoietic Stem and Progenitor Cellscall_made
Stem Cells, 10.1002/stem.3205
Bernitz JM, Rapp K, Daniel MG, Shcherbinin D, Yuan Y, Gomes A, Waghray A, Brosh R, Lachmann A, Ma'ayan A, Papatsenko D, Moore KA (2020)
external pageMemory of Divisional History Directs the Continuous Process of Primitive Hematopoietic Lineage Commitmentcall_made
Stem Cell Reports, 14(4): 561–574.
Matos ÂP, Kauffman A, Vickery C, Naegeli K, Strittmatter L, Sybirna A, van Blijswijk J, Adlung L, Berbasova T, Enterina J, Eismann L, Tierney B, Jordi J, Zhu L, Verkuijl S, Tallorin L, Wehling A, Ogden M, Lammel S, Hasslacher MK, Wuelfroth P, Neumann S, Tidona C, Betz UAK (2020)
external pageSynthetic Biology Category Wins the 350th Anniversary Merck Innovation Cupcall_made
Trends in Biotechnology, 38(1):1-4
2019
Loeffler D, Wehling A, Schneiter F, Zhang Y, Müller-Bötticher N, Hoppe PS, Hilsenbeck O, Kokkaliaris K, Endele M and Schroeder T (2019)
external pageAsymmetric lysosome inheritance predicts activation of haematopoietic stem cellscall_made
Nature, 573(7774):426-429
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Kunz L and Schroeder T (2019)
external pageA 3D tissue-wide digital imaging pipeline for quantitation of secreted molecules shows absence of CXCL12 gradients in bone marrowcall_made
Cell Stem Cell, 25(6):846-854
Etzrodt M*, Ahmed N*, Hoppe PS, Loeffler D, Skylaki S, Hilsenbeck O, Kokkaliaris KD, Kaltenbach HM, Stelling J, Nerlov C and Schroeder T (2019)
external pageInflammatory signals directly instruct PU.1 in HSCs via TNFcall_made
Blood, blood-2018-02-832998
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Loeffler D and Schroeder T (2019)
external pageUnderstanding Cell Fate Control by Continuous Single Cell Quantificationcall_made
Blood, blood-2018-09-835397
Bourgine PE, Fritsch K, Pigeot S, Takizawa H, Kunz L, Kokkaliaris KD, Coutu DL, Manz MG, Martin I, Schroeder T (2019)
external pageFate Distribution and Regulatory Role of Human Mesenchymal Stromal Cells in Engineered Hematopoietic Bone Organscall_made
iScience, 19:504-513
Tyrkalska SD, Pérez-Oliva AB, Rodríguez-Ruiz L, Martínez-Morcillo FJ, Alcaraz-Pérez F, Martínez-Navarro FJ, Josselin E, Lachaud C, Ahmed N, Schroeder T, Pardo-Sánchez I, Candel S, López-Muñoz A, Choudhuri A, Rossmann MP, Zon LI, Cayuela ML, García-Moreno D, Mulero V (2019)
external pageInflammasome regulates hematopoiesis through cleavage of the master erythroid transcription factor GATA1call_made
Immunity, 51(1):50-63
McKenzie MD, Ghisi M, Oxley EP, Ngo S, Cimmino L, Esnault C, Liu R, Salmon JM, Bell CC, Ahmed N, Erlichster M, Witkowski MT, Liu GJ, Chopin M, Dakic A, Simankowicz E, Pomilio G, Vu T, Krsmanovic P, Su S, Tian L, Baldwin TM, Zalcenstein DA, DiRago L, Wang S, Metcalf D, Johnstone RW, Croker BA, Lancaster GI, Murphy AJ, Naik SH, Nutt SL, Pospisil V, Schroeder T, Wall M, Dawson MA, Wei AH, De The H, Ritchie ME, Zuber J, Dickins RA (2019)
external pageInterconversion between tumorigenic and differentiated states in acute myeloid leukemiacall_made
Cell Stem Cell, 25(2):258-272
Berge U, Bochenek D, Schnabel R, Wehling A, Schroeder T, Stadler T, Kroschewski R (2019)
external pageAsymmetric division events promote variability in cell cycle duration in animal cells and Escherichia colicall_made
Nature Communications, 10(1):1901
Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T and Woltjen K (2019)
external pageOVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediatescall_made
Stem Cell Reports, 12(2):319-332
Failmezger H, Dursun E, Dümcke S, Endele M, Poron D, Schroeder T, Krug A and Tresch A (2019)
external pageClustering of samples with a tree-shaped dependence structure, with an application to microscopic time lapse imagingcall_made
Bioinformatics, 10.1093/bioinformatics/bty939
2018
Coutu DL* / **, Kokkaliaris KD*, Kunz L* and Schroeder T** (2018)
external pageMulticolor quantitative confocal imaging cytometrycall_made
Nature Methods, 15: 39-46
Hastreiter S, Skylaki S, Loeffler D, Reimann A, Hilsenbeck O, Hoppe PS, Coutu DL, Kokkaliaris KD, Schwarzfischer M, Anastassiadis K, Theis FJ and Schroeder T (2018)
external pageInductive and selective effects of GSK3 and MEK inhibition on Nanog heterogeneity in embryonic stem cellscall_made
Stem Cell Reports, 11(1):58-69
Bourgine PE*, Klein T*, Paczula A, Shimizu T, Kunz L, Kokkaliaris KD, Coutu DL, Lengerke C, Skoda R, Schroeder T** and Martin I** (2018) **corresponding author
external pageIn vitro biomimetic engineering of a human hematopoietic niche with functional propertiescall_made
PNAS, 115(25):E5688-E5695
Loeffler D, Wang W, Hopf A, Hilsenbeck O, Bourgine PE, Rudolf F, Martin I and Schroeder T (2018)
external pageMouse and human HSPC immobilization in liquid culture by CD43/CD44-antibody coatingcall_made
Blood, 131(13):1425-1429
Strasser MK, Hoppe P, Loeffler D, Kokkaliaris K, Schroeder T**, Theis FJ and Marr C** (2018) **corresponding author
external pageLineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigmcall_made
Nature Communications, 9(1):2697
Bourgine PE, Martin I and Schroeder T (2018)
external pageEngineering human bone marrow proxiescall_made
Cell Stem Cell, 22(3):298-301
Dettinger P*, Frank T*, Etzrodt M*, Ahmed N, Reimann A, Trenzinger C, Loeffler D, Kokkaliaris KD, Schroeder T** and Savas Tay** (2018) **corresponding author
external pageAutomated microfluidic system for dynamic stimulation and tracking of single cellscall_made
Analytical Chemistry, 90(18):10695–10700
Stadler T*, Skylaki S, Kokkaliaris KD and Schroeder T* (2018)
external pageOn the statistical analysis of single cell lineage treescall_made
Journal of Theoretical Biology, 439: 160-165
Kawamura S and Ohteki T (2018)
external pageMonopoiesis in humans and micecall_made
International Immunology, 30(11):503-509
Frick C, Dettinger P, Renkawitz J, Jauch A, Berger C, Recher M, Schroeder T and Mehling M (2018)
external pageNano-scale microfluidics to study 3D chemotaxis at the single cell levelcall_made
PLoS ONE, 13(6):e0198330
Shepherd MS, Li J, Wilson NK, Oedekoven CA, Li J, Belmonte M, Fink J, Prick JCM, Pask DC, Hamilton TL, Löffler D, Rao A, Schroeder T, Göttgens B, Green AR and Kent DG (2018)
external pageSingle cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewalcall_made
Blood, blood-2017-12-821066
Fritsch K, Pigeot S, Feng X, Bourgine PE, Schroeder T, Martin I, Manz MG and Takizawa H (2018)
external pageEngineered humanized bone organs maintain human hematopoiesis in vivocall_made
Experimental Hematology, 61:45-51
Montaner A, da Silva Santana TT, Schroeder T, Einiker-Lamas M, Girardini J, Costa MR and Banchio C (2018).
external pageSpecific Phospholipids Regulate the Acquisition of Neuronal and Astroglial Identities in Post-Mitotic Cellscall_made
Scientific Reports, 8: 460
Landeira BS, Santana TT, Araújo JA, Tabet EI, Tannous BA, Schroeder T, Costa MR (2018)
external pageActivity-Independent Effects of CREB on Neuronal Survival and Differentiation during Mouse Cerebral Cortex Developmentcall_made
Cereb Cortex, 28: 538-548
May M, Denecke B, Schroeder T, Götz M and Faissner A (2018)
external pageCell tracking in vitro reveals that the extracellular matrix glycoprotein Tenascin-C modulates cell cycle length and differentiation in neural stem/progenitor cells of the developing mouse spinal cordcall_made
Biology Open, 7: bio027730
Saitou K, Tokunaga M, Yoshino D, Sakitani N, Maekawa T, Ryu Y, Nagao M, Nakamoto H, Saito T, Kawanishi N, Suzuki K, Ogata T, Makuuchi M, Takashima A, Sawada K, Kawamura S, Nakazato K, Kouzaki K, Harada I, Ichihara Y and Sawada Y (2018)
external pageLocal Cyclical Compression Modulates Macrophage Function In Situ and Alleviates Immobilization-Induced Muscle Atrophycall_made
Clinical Science, 132(19): 2147-2161
2017
Coutu DL*, Kokkaliaris KD*, Kunz L and Schroeder T (2017)
external pageThree-dimensional map of non-hematopoietic bone and bone marrow cells and moleculescall_made
Nature Biotechnology, 35: 1202–1210
Endele M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Skylaki S, Hoppe PS, Schambach A, Stanley RE and Schroeder T (2017)
external pageCSF-1 induced Src signaling can instruct monocytic lineage choicecall_made
Blood, 129: 1691-1701
Hilsenbeck O, Schwarzfischer M, Loeffler D, Dimopoulos S, Hastreiter S, Marr C, Theis FJ and Schroeder T (2017)
external pagefastER: a user-friendly tool for ultrafast and robust cell segmentation in large-scale microscopycall_made
Bioinformatics, 33: 2020-2028
Buggenthin F, Buettner F, Hoppe PS, Endele M, Kroiss M, Strasser M, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Schroeder T*, Theis FJ* and Marr C* (2017) *corresponding author
external pageProspective identification of hematopoietic lineage choice by deep learningcall_made
Nature Methods, 14: 403-406
Wang W, Fujii H, Kim HJ, Hermans K, Usenko T, Xie S, Luo ZJ, Ma J, Lo Celso C, Dick JE, Schroeder T, Krueger J, Wall D, Egeler RM, Zandstra PW (2017)
external pageEnhancement of human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated tumor necrosis factor alpha signalingcall_made
Sci Transl Med, 9(421)
Etzrodt M and Schroeder T (2017)
external pageIlluminating stem cell transcription factor dynamics: Long-term single-cell imaging of fluorescent protein fusionscall_made
Current Opinion in Biology, 49: 77-83
Cabezas-Wallscheid N, Buettner F, Sommerkamp P, Klimmeck D, Ladel L, Thalheimer F, Pastor-Flores D, Roma L, Renders S, Zeisberger P, Przybylla A, Schönberger K, Scognamiglio R, Altamura S, Florian CM, Fawaz M, Vonficht D, Tesio M, Collier P, Pavlinik D, Geiger H, Schroeder T, Benes V, Dick TP, Rieger MA, Stegle O and Trumpp A (2017)
external pageVitamin A/ Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancycall_made
Cell, 169: 807-823.e19
Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, Alexe G, Corso J, Ströbel P, Wachter A, Beissbarth T, Schnütgen F, Cremer A, Haetscher N, Göllner S, Rouhi A, Palmqvist L, Rieger MA, Schroeder T, Bönig H, Müller-Tidow C, Kuchenbauer F, Schütz E, Green AR, Urlaub H, Stegmaier K, Humphries RK, Serve H and Oellerich T (2017)
external pageHoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemiacall_made
Cancer Cell, 31: 549-562
Lang F, Wojcik B, Bothur S, Knecht C, Falkenburg FJH, Schroeder T, Serve H, Ottmann OG, Rieger MA (2017)
external pagePlastic CD34 and CD38 expression in adult B-precursor acute lymphoblastic leukemia explains ambiguity of leukemia-initiating stem cell populationscall_made
Leukemia, 31:731-734
Peng T, Thorn K, Schroeder T, Wang L, Theis F, Marr C, Navab N (2017)
external pageA BaSiC Tool for Background and Shading Correction of Optical Microscopy Imagescall_made
Nature Communications, 8: 14836
Yuan GC, Cai L, Elowitz M, Enver T, Fan G, Guo G, Irizarry R, Kharchenko P, Kim J, Orkin S, Quackenbush J, Saadatpour A, Schroeder T, Shivdasani R, Tirosh I (2017)
external pageChallenges and emerging directions in single-cell analysiscall_made
Genome Biology, 18:84
Kellogg RA, Tian C, Etzrodt M, Tay S (2017)
external pageCellular Decision Making by Non-Integrative Processing of TLR Inputscall_made
Cell Reports, 19: 125-135
Chouchane M, Melo de Farias AR, Moura DMS, Hilscher MM, Schroeder T, Leão RN, Costa MR (2017)
external pageLineage Reprogramming of Astroglial Cells from Different Origins into Distinct Neuronal Subtypescall_made
Stem Cell Reports, 9: 162-176
Landeira BS, Alves de Medeiros Araújo J, Schroeder T, Müller U, Costa MR (2017)
external pageLive imaging of primary cerebral cortex cells using a 2D culture systemcall_made
JoVE, 126
Gomez-Villafuertes R, Paniagua-Herranz L, Gascón S, de Agustin-Duran D, de la O Ferreras M, Gil-Redondo JC, José Queipo M, Menendez-Mendez A, Pérez-Sen R, Delicado EG, Gualix J, Costa MR, Schroeder T, Miras-Portugal MT, Ortega F (2017)
external pageLive imaging followed by single cell tracking to monitor cell biology and lineage progression of multiple neural populationscall_made
JoVe, 130
2016
Hoppe PS, Schwarzfischer M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Moritz N, Endele M, Filipczyk A, Gambardella A, Ahmed N, Etzrodt M, Coutu DL, Rieger MA, Marr C, Strasser M, Schauberger B, Burtscher I, Ermakova O, Bürger A, Lickert H, Nerlov C, Theis FJ and Schroeder T (2016)
external pageEarly myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratioscall_made
Nature, 535: 299-302
Hilsenbeck O*, Schwarzfischer M*, Skylaki S*, Schauberger B, Hoppe PS, Loeffler D, Kokkaliaris KD, Hastreiter S, Skylaki E, Filipczyk A, Strasser M, Buggenthin F, Feigelman JS, Krumsiek J, van den Berg AJJ, Endele M, Etzrodt M, Marr C, Theis FJ* and Schroeder T* (2016)
external pageSoftware tools for single-cell tracking and quantification of cellular and molecular propertiescall_made
Nature Biotechnology, 34: 703-706
Kokkaliaris KD, Drew E, Endele M, Loeffler D, Hoppe PS, Hilsenbeck O, Schauberger B, Hinzen C, Skylaki S, Theodorou M, Kieslinger M, Lemischka I, Moore K and Schroeder T (2016)
external pageIdentification of factors promoting ex vivo maintenance of hematopoietic stem cells by long-term single-cell quantificationcall_made
Blood, 128:1181-92
- Highlighted in this external pagepreviewcall_made
Skylaki S, Hilsenbeck O and Schroeder T (2016)
external pageChallenges in long-term imaging and quantification of single cell dynamicscall_made
Nature Biotechnology, 34: 1137-1144
Hastreiter S and Schroeder T (2016)
external pageNanog dynamics in single embryonic stem cellscall_made
Cell Cycle, 15: 770-771
Kokkaliaris KD*, Lucas D*, Beerman I*, Kent DG, Perié L. (2016)
external pageUnderstanding hematopoiesis from a single-cell standpointcall_made
Exp Hematol, 44: 447-450
* equal contribution
Pietras M, Mirantes-Barbeito C, Fong S, Loeffler D, Kovtonyuk LV, Zhang SY, Lakshminarasimhan R, Chin CP, Techner J-M, Will B, Nerlov C, Steidl U, Manz MG, Schroeder T, Passegué E. (2016)
external pageInterleukin-1 drives hematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewalcall_made
Nature Cell Biology, 18: 607-618
Gascón S, Murenu E, Masserdotti G, Ortega F, Russo GL, Petrik D, Deshpande A, Heinrich C, Karow M, Robertson SP, Schroeder T, Beckers J, Irmler M, Berndt C, Angeli JP, Conrad M, Berninger B, Götz M. (2016)
external pageIdentification and Successful Negotiation of a Metabolic Checkpoint in Direct Neuronal Reprogrammingcall_made
Cell Stem Cell, 18: 396-409
Canli Ö, Alankuş YB, Grootjans S, Vegi N, Hültner L, Hoppe PS, Schroeder T, Vandenabeele P, Bornkamm GW and Greten FR (2016)
external pageGlutathione peroxidase 4 prevents necroptosis in mouse erythroid precursorscall_made
Blood, 127: 139-148
Fagnocchi L, Cherubini A, Hatsuda H, Fasciani A, Mazzoleni S, Poli V, Berno V, Rossi R, Reinbold R, Endele M, Schroeder T, Rocchigiani M, Szkarłat Z, Oliviero S, Dalton S, Zippo A. (2016)
external pageA Myc-driven self-reinforcing regulatory network maintains mouse embryonic stem cell identitycall_made
Nature Communications, 7: 11903
Wingert S, Thalheimer FB, Haetscher N, Rehage M, Schroeder T, Rieger MA. (2016)
external pageThe DNA-damage response gene GADD45A induces differentiation in hematopoietic stem cells without inhibiting cell cycle or survivalcall_made
Stem Cells, 34: 699-710
Birchler A, Berger M, Jäggin V, Lopes T, Etzrodt M, Misun PM, Pena-Francesch M, Schroeder T, Hierlemann A, Frey O. (2016)
external pageSeamless Combination of Fluorescence-Activated Cell Sorting and Hanging-Drop Networks for Individual Handling and Culturing of Stem Cells and Microtissue Spheroidscall_made
Analytical Chemistry, 88: 1222-1229
Feigelman J, Ganscha S, Hastreiter S, Schwarzfischer M, Filipczyk A, Schroeder T, Theis FJ, Marr C, Claassen M (2016)
external pageAnalysis of cell lineage trees by exact Bayesian inference identifies negative autoregulation of Nanog in mouse embryonic stem cells.call_made
Cell Systems, 3: 480-490
Dursun E, Endele M, Musumecia A, Failmezger H, Wang SH, Tresch A, Schroeder T and Krug AB (2016)
external pageContinuous single cell imaging reveals sequential steps of plasmacytoid dendritic cell development from common dendritic cell progenitorscall_made
Scientific Reports, 6: 37462
Cornwell JA, Hallet JR, Auf der Mauer S, Motazedian A, Schroeder T, Draper JS, Harvey RP and Nordon RE (2016)
external pageQuantifying intrinsic and extrinsic control of single-cell fates in cancer and stem/progenitor cell pedigrees with competing risks analysiscall_made
Scientific Reports, 6: 27100
Engert A, and the authors of the EHA Roadmap for European Hematology Research (incl. Schroeder T) (2016)
external pageThe European Hematology Association Roadmap for European Hematology Research: a consensus documentcall_made
Haematologica, 101: 115-208
Sarroca S, Molina-Martínez P, Aresté C, Etzrodt M, García de Frutos P, Gasa R, Antonell A, Molinuevo JL, Sánchez-Valle R, Saura CA, Lladó A, Sanfeliu C (2016)
external pagePreservation of cell-survival mechanisms by the presenilin-1 K239N mutation may cause its milder clinical phenotypecall_made
Neurobiol. Aging, 46:169-79.
2015
Filipczyk A*, Marr C*, Hastreiter S*, Feigelman J, Schwarzfischer M, Hoppe PS, Loeffler D, Kokkaliaris KD, Endele M, Schauberger B, Hilsenbeck O, Skylaki S, Hasenauer J, Anastassiadis K, Theis FJ* and Schroeder T* (2015)
external pageNetwork plasticity of pluripotency transcription factors in embryonic stem cellscall_made
Nature Cell Biology, 17: 1235-1246
Walter D, Lier A, Geiselhart A, Thalheimer F, Huntscha S, Sobotta M, Moehrle B, Brocks D, Bayindir I, Kaschutnig P, Muedder K, Klein C, Jauch A, Schroeder T, Geiger H, Dick T, Holland-Letz T, Schmezer P, Lane SW, Rieger MA, Essers MAG, Williams DA, Trumpp A and Milsom MD (2015)
external pageExit from dormancy provokes de novo DNA damage-induced cellular attrition in haematopoietic stem cellscall_made
Nature, 520: 549-552
Haas S, Hanson U, Klimmeck D, Loeffler D, Velten L, Uckelmann H, Wurzer S, Prendergast AM, Schnell A, Hexel K, Santarella-Mellwig R, Blaszkiewicz S, Kuck A, Geiger H, Milsom MD, Steinmetz LM, Schroeder T, Trumpp A, Krijgsveld J, Essers MAG (2015)
external pageInflammation-induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitorscall_made
Cell Stem Cell, 17: 422-434
Mende N, Kuchen EE, Lesche M, Grinenko T, Kokkaliaris KD, Hanenberg H, Lindemann D, Dahl A, Platz A, Höfer T, Calegari F, Waskow C. (2015)
external pageCCND1-CDK4-mediated cell cycle progression provides a competitive advantage for human hematopoietic stem cells in vivo.call_made
J Exp Med, 212: 1171-1183
Rabenhorst U, Thalheimer FB, Gerlach K, Kijonka M, Böhm S, Krause D, Vauti F, Arnold HH, Schroeder T, Schnütgen F, von Melchner H, Rieger MA, Zörnig M (2015)
external pageSingle-stranded DNA-binding transcriptional regulator FUBP1 is essential for fetal and adult hematopoietic stem cell self-renewalcall_made
Cell Reports, 11: 1847-1855
Haetscher N, Feuermann Y, Wingert S, Rehage M, Thalheimer F, Weiser C, Bohnenberger H, Jung K, Schroeder T, Serve H, Oellerich T, Hennighausen L and Rieger MA (2015)
external pageSTAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signallingcall_made
Nature Communications, 6: 8928
Sekhavati F, Endele M, Rappl S, Marel AK, Schroeder T, Rädler JO (2015)
external pageMarker-Free Detection of Progenitor Cell Differentiation by Analysis of Brownian Motion in Micro-Wellscall_made
Integrative Biology, 7: 178-183
Yilmaz A, Engeler R, Constantinescu S, Kokkaliaris KD, Dimitrakopoulos C, Schroeder T, Beerenwinkel N and Paro R (2015)
external pageEctopic expression of Msx2 in mammalian myotubes recapitulates aspects of amphibian muscle dedifferentiation.call_made
Stem Cell Research, 15: 542-553
Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K. (2015)
external pageReprogramming Roadblocks Are System Dependent.call_made
Stem Cell Reports, 5: 350-364
Niederberger T, Failmezger H, Uskat D, Poron D, Glauche I, Scherf N, Roeder I, Schroeder T and Tresch A (2015)
external pageFactor graph analysis of live cell imaging data reveals mechanisms of cell fate decisionscall_made
Bioinformatics, 31: 1816-1823
Sykes SM*, Kokkaliaris KD*, Milsom MD*, Levine RL, Majeti R. (2015)
external pageClonal evolution of pre-leukemic hematopoietic stem cells in acute myeloid leukemia.call_made
Experimental Hematology, 43: 989-992
2014
Etzrodt M, Endele M and Schroeder T (2014)
external pageQuantitative single-cell approaches to stem cell researchcall_made
Cell Stem Cell, 15: 546-558
Hoppe PS, Coutu DL, Schroeder T (2014)
external pageSingle-cell technologies sharpen up mammalian stem cell researchcall_made
Nature Cell Biology, 16: 919-927
Endele M, Etzrodt M and Schroeder T (2014)
external pageInstruction of hematopoietic lineage choice by cytokine signalingcall_made
Experimental Cell Research, 329: 207-213
Coutu DL, Mahfouz W, Loutochin O, Galipeau J, Corcos J (2014)
external pageTissue engineering of rat bladder using marrow-derived mesenchymal stem cells and bladder acellular matrix.call_made
PLoS One, 9: e111966
Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B, DIAGRAM+ Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H and Laumen H (2014)
external pageLeveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms.call_made
Cell, 156: 343-358
Tanaka Y, Sanchez V, Takata N, Yokomizo T, Yamanaka Y, Kataoka H, Hoppe PS, Schroeder T and Nishikawa SI (2014)
external pageCirculation-Independent Differentiation Pathway from Extraembryonic Mesoderm toward Hematopoietic Stem Cells via Hemogenic Angioblastscall_made
Cell Reports, 8: 31-39
Hasemann MS, Lauridsen FKB, Waage J, Jakobsen JS, Frank AK, Schuster MB, Rapin N, Bagger FO, Hoppe PS, Schroeder T and Porse BT (2014)
external pageC/EBPα Is Required for Long-Term Self-Renewal and Lineage Priming of Hematopoietic Stem Cells and for the Maintenance of Epigenetic Configurations in Multipotent Progenitorscall_made
PLoS Genetics, 10: e1004079
Thalheimer FB, Wingert S, De Giacomo P, Haetscher N, Rehage M, Brill B, Theis F, Hennighausen L, Schroeder T, Rieger MA (2014)
external pageCytokine-regulated Gadd45γ induces differentiation and lineage selection in hematopoietic stem cellscall_made
Stem Cell Reports, 3: 34-43
Khakhutskyy V, Schwarzfischer M, Hubig N, Plant C, Marr C, Rieger MA, Schroeder T and Theis FJ (2014)
external pageCentroid clustering of cellular lineage treescall_made
Lecture Notes in Computer Science, 8649: 15-29
Pertek A, Meier F, Irmler M, Beckers J, Skylaki S, Endele M, Wurst W, Prakash N, Kühn R. (2014)
external pageSimple Derivation of Transgene-Free iPS Cells by a Dual Recombinase Approach.call_made
Molecular Biotechnology, 56: 697-713
Cabrera CM, Tilahun E, Nakles R, Diaz-Cruz ES, Charabaty A, Suy S, Jackson P, Ley L, Slack R, Jha R, Collins SP, Haddad N, Kallakury BVS, Schroeder T, Pishvaian MJ, and Furth P (2014)
external pageHuman pancreatic cancer-associated stellate cells remain activated after in vivo chemoradiationcall_made
Frontiers in Oncology, 4: 102
Araújo GLL, Araújo JAM, Schroeder T, Tort ABL, Costa MR (2014)
external pageSonic hedgehog signaling regulates mode of cell division of early cerebral cortex progenitors and increases astrogliogenesiscall_made
Frontiers in Neuroscience, 8: 77
Coutu DL* and Galipeau J. (2014) *corresponding author
Molecular and endocrine mechanisms underlying the stem cell theory of aging.
Adult stem cells (K.Turksen ed.), pp.389-417
Trompouki E, King KY, Will B, Lessard J, Flores-Figueroa E, Kokkaliaris KD, Bowman T (2014)
external pageBloody signals: From birth to disease and death.call_made
Experimental Hematology, 42: 989-994
Tsakiridis A, Huang Y, Blin G, Skylaki S, Wymeersch F, Osorno R, Economou C, Karagianni E, Zhao S, Lowell S and Wilson V (2014)
external pageDistinct Wnt-driven primitive streak-like populations reflect in vivo lineage precursors.call_made
Development, 141: 1209-1221
2013
Filipczyk A, Gkatzis K, Fu J, Hoppe PS, Lickert H, Anastassiadis K and Schroeder T (2013)
external pageBiallelic expression of nanog protein in mouse embryonic stem cellscall_made
Cell Stem Cell, 13: 12-31
Coutu DL and Schroeder T (2013)
external pageProbing cellular processes by long-term live imaging – historic problems and current solutionscall_made
Journal of Cell Science, 126: 3805-3815
Schroeder T (2013)
external pageHeterogeneity of sister cell fatescall_made
Nature Reviews Molecular Cell Biology, 14: 327
O’Malley J, Skylaki S, Iwabuchi KA, Chantzoura E, Ruetz T, Johnsson A, Tomlinson SR, Linnarsson S and Kaji K (2013)
external pageHigh resolution analysis with novel cell-surface markers identifies routes to iPS cellscall_made
Nature, 499: 88-91
Ortega F, Gascón S, Masserdotti G, Deshpande A, Simon C, Fischer J, Dimou L, Lie DC, Schroeder T and Berninger B (2013)
external pageOligodendrogliogenic and neurogenic adult subependymal zone neural stem cells constitute distinct lineages and exhibit differential responsiveness to Wnt signallingcall_made
Nature Cell Biology, 15: 602-613
Rengstl B, Newrzela S, Heinrich T, Weiser C, Thalheimer FB, Schmid F, Warner K, Hartmann S, Schroeder T, Küppers R, Rieger MA and Hansmann ML (2013)
external pageIncomplete cytokinesis and re-fusion of small mononucleated Hodgkin cells lead to giant multinucleated Reed-Sternberg cellscall_made
PNAS, 110: 20729-20734
Swiers G, Baumann C, O’Rourke J, Giannoulatou E, Taylor S, Joshi A, Moignard V, Pina C, Bee T, Kokkaliaris KD, Yoshimoto M, Yoder M, Frampton J, Schroeder T, Enver T, Gottgens B and de Bruijn MFTR (2013)
external pageEarly dynamic fate changes in haemogenic endothelium characterised at the single cell levelcall_made
Nature Communications, 4:2924
Müller TD, Lee SJ, Jastroch M, Kabra D, Stemmer K, Aichler M, Abplanalp B, Ananthakrishnan G, Bhardwaj N, Collins S, Divanovic S, Endele M, Finan B, Gao Y, Habegger KM, Hembree J, Heppner KM, Hofmann S, Holland J, Küchler D, Kutschke M, Krishna R, Lehti M, Oelkrug R, Ottaway N, Perez-Tilve D, Raver C, Walch AK, Schriever SC, Speakman J, Tseng YH, Diaz-Meco M, Pfluger PT, Moscat J and Tschöp MH. (2013)
external pagep62 links β-adrenergic input to mitochondrial function and thermogenesis.call_made
J Clin Invest, 123: 469-478
Montrone C, Kokkaliaris KD, Loeffler D, Lechner M, Kastenmüller G, Schroeder T and Ruepp A (2013)
external pageHSC-Explorer: a curated database for hematopoietic stem cellscall_made
PLoS One, 8: e70348
Buggenthin F, Marr C, Schwarzfischer M, Hoppe PS, Hilsenbeck O, Schroeder T and Theis FJ (2013)
external pageAn automatic pipeline for robust cell detection in bright field images of high-throughput microscopycall_made
BMC Bioinformatics, 14: 297
Nakles RE, Millman S, Cabrera MC, Johnson P, Mueller S, Hoppe PS, Schroeder T and Furth PA (2013)
external pageTime-lapse Imaging of Primary Preneoplastic Mammary Epithelial Cells Derived from Genetically Engineered Mouse Models of Breast Cancercall_made
J Vis Exp, 72: e50198
Gewies A, Castineiras-Vilarino M, Ferch U, Jährling N, Heinrich K, Hoeckendorf U, Przemeck GKH, Munding M, Gross O, Schroeder T, Horsch M, Karran EL, Majid A, Antonowicz S, Beckers J, Hrabé de Angelis M, Dodt HU, Peschel C, Foerster I, Dyer MJS and Ruland J (2013)
external pagePrdm6 Is Essential for Cardiovascular Development In Vivocall_made
PLoS ONE, 8: e81833
Despars G, Carbonneau CL, Bardeau P, Coutu DL and Beauséjour CM (2013)
external pageLoss of the osteogenic differentiation potential during senescence is limited to bone progenitor cells and is dependent on p53call_made
PLoS One, 8: e73206
2012
Rieger MA and Schroeder T (2012)
Hematopoiesis
Cold Spring Harb Perspect Biol, 4
and book: Mammalian Development: Networks, Switches, and Morphogenetic Processes
Cold Spring Harbor Laboratory Press, edited by Nelson, Rossant and Tam
Chambers I and Schroeder T (2012)
external pageStem cell powwow in Squaw Valleycall_made
Development, 139: 2457-2461
Endele M and Schroeder T (2012)
external pageMolecular live cell bioimaging in stem cell researchcall_made
Hematopoietic Stem Cells VIII
Annals of the New York Academy of Sciences, 1266: 18-27
Kokkaliaris KD, Loeffler D and Schroeder T (2012)
external pageAdvances in tracking Hematopoiesis at the single-cell levelcall_made
Current Opinion in Hematology, 19: 243-249
Marr C, Strasser M, Schwarzfischer M, Schroeder T and Theis FJ (2012)
external pageMulti-scale modeling of GMP differentiation based on single-cell genealogiescall_made
FEBS Journal, 279: 3488-3500
2011
Schroeder T (2011)
external pageLong-term single-cell imaging of mammalian stem cellscall_made
Nature Methods, 8: S30-35
Loeffler D, Kokkaliaris KD and Schroeder T (2011)
external pageWnt to notch relay signaling induces definitive hematopoiesiscall_made
Cell Stem Cell, 9: 2-4
Warlich E, Kühle J, Cantz T, Brugman M, Maetzig T, Galla M, Filipczyk AA, Foerster R, Klump H, Schöler HR, Baum C, Schroeder T* and Schambach A* (2011) * corresponding author
external pageLentiviral vector design and imaging approaches to visualize the early stages of cellular reprogrammingcall_made
Molecular Therapy, 19: 782-789
Nordon RE, Ko KH, Odell R and Schroeder T (2011)
external pageMulti-type branching models to describe cell differentiation programscall_made
Journal of Theoretical Biology, 277: 7-18
Eilken HM, Rieger MA, Hoppe PS, Hermann AC, Smejkal BM, Drew EC, Thum M, Ninkovic J, Beckervordersandforth RM and Schroeder T (2011)
external pageContinuous long-term detection of live cell surface markers by ‘in culture’ antibody stainingcall_made
Protocols Exchange, DOI: 10.1038/protex.2011.205
Heinrich C, Gascón S, Masserdotti G, Lepier A, Sánchez R, Simon-Ebert T, Schroeder T, Götz M and Berninger B (2011)
external pageGeneration of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortexcall_made
Nature Protocols, 6: 214-228
Ortega F, Costa MR, Simon-Ebert T, Schroeder T, Götz M and Berninger B (2011)
external pageUsing an adherent cell culture of the mouse subependymal zone to study the behavior of adult neural stem cells on a single-cell levelcall_made
Nature Protocols, 6: 1847-1859
Costa M, Ortega F, Brill M, Beckervordersandforth-Bonk R, Petrone C, Schroeder T, Götz M and Berninger B (2011)
external pageContinuous live imaging of adult neural stem cell division and lineage progression in vitrocall_made
Development, 138: 1057-1068
Asami M, Pilz G, Ninkovic J, Godinho L, Schroeder T, Huttner W and Götz M (2011)
external pageThe role of Pax6 in regulating the orientation and mode of cell division of progenitors in the mouse cerebral cortexcall_made
Development, 138: 5067-5078
Krumsiek J, Marr C, Schroeder T and Theis FJ (2011)
external pageHierarchical differentiation of myeloid progenitors is encoded in the regulatory logic of the transcription factor networkcall_made
PLoS One, 6: e22649
Tonge PD, Shigeta M, Schroeder T, Andrews PW (2011)
external pageFunctionally Defined Substates within the Human Embryonic Stem Cell Compartmentcall_made
Stem Cell Research, 7:145-153
Roeder I, Loeffler M, Glauche I, Bornhaeuser M, Buske P, Clarke G, Cross M, Efroni S, Ilan B, Essers M, Galle J, Giangreco A, Glauche I, Griessinger E, Hoppe P, Kobel S, Krinner A, Lauffenburger D, Lemischka I, LoCelso C, Loeffler M, Lutolf M, Moore K, Nazareth E, Oostendorp R, Palmer M, Pompe T, Rocheteau P, Roeder I, Scherf N, Schroeder T, Tajbakhsh S, Vilne B, van der Wath R, Waskow C, Werner C, Yaromina A, Zandstra P (2011)
external pageTowards a quantitative understanding of stem cell–niche interaction: Experiments, models, and technologiescall_made
Blood Cells, Molecules, and Diseases, 46: 308-317
Schwarzfischer M, Marr C, Krumsiek J, Hoppe PS, Schroeder T and Theis FJ (2011)
Efficient fluorescent image normalization for time lapse movies
Proc. Microscopic Image Analysis with Applications in Biology, Heidelberg, Germany, 2. Sept. 2011
Coutu, D.L. & Galipeau, J. (2011)
external pageRoles of FGF signaling in stem cell self-renewal, senescence and agingcall_made
Aging, 3: 920-933
- Nature Technology Feature on Single Cell Analysis highlighting our approaches:
Schubert C (2011)
The deepest differences
Nature, 480: 133 - 137 - Nature Jobs Feature on Single Cell Imaging highlighting our facility:
Maxmen A (2011)
Single-cell analysis: Imaging is everything
Nature, 480: 139 - 141
2010
Schroeder T (2010)
external pageHematopoietic stem cell heterogeneity: Subtypes, not unpredictable behaviorcall_made
Cell Stem Cell, 6: 203-207
Schroeder T (2010)
external pageThe electronic crystal ball: Predicting cell fate from time lapse datacall_made
Nature Methods, 7: 190–191
Ninkovic J, Pinto L, Petricca S, Rieger MA, Schroeder T, Ashery-Padan R, Favor J and Götz M (2010)
external pageThe transcription factor Pax6 regulates survival of dopaminergic olfactory bulb neurons via crystallin alphacall_made
Neuron, 68: 682-694
Heinrich C, Blum R, Gascon S, Masserdotti G, Tripathi P, Sánchez R, Tiedt S, Schroeder T, Götz M and Berninger B (2010)
external pageDirecting Astroglia from the Cerebral Cortex into Subtype Specific Functional Neuronscall_made
PLoS Biology, 8: e1000373
- Stocking C, Grez M, Fehse B, von Laer D, Itoh K, Prassolov V, Nowock J, Kühlcke K, Just U, Schroeder T, Klump H, Schiedlmeier B, Grassman E, Meyer J, Li Z, Schambach A, Modlich U, Kustikova O, Galla M, Bode J, Zander A, Baum C. (2010)
external pageCell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertagcall_made
Human Gene Therapy, 21: 1501-1503. - Nature Technology Feature on 'Cellular Imaging', highlighting our novel bioimaging approaches: Baker M (2010)
external pageCellular imaging: Taking a long, hard lookcall_made
Nature, 466: 1137 - 1140
2009
Rieger MA, Hoppe PS, Smejkal BM, Eitelhuber AC and Schroeder T (2009)
external pageHematopoietic cytokines can instruct lineage choicecall_made
Science, 325: 217 - 218
- (P)Reviews in scientific journals:
external pageScience Signalingcall_made
external pageNature Reports Stem Cellscall_made
external pageNature Reviews Immunologycall_made
external pageCell Stem Cellcall_made
external pageNaturecall_made
Eilken HM, Nishikawa SI and Schroeder T (2009)
external pageContinuous single-cell imaging of blood generation from haemogenic endotheliumcall_made
Nature, 457: 896 - 900
- (P)Reviews in scientific journals:
external pageNaturecall_made
external pageCell Stem Cellcall_made
external pageNature Reports Stem Cellscall_made
external pageNature Reviews Molecular Cell Biologycall_made
external pageNaturecall_made
Kimura A*, Rieger MA*, Simone JM, Chen W, Wickre MC, Zhu BM, Hoppe PS, O’Shea J, Schroeder T** and Hennighausen L** (2009)
* and ** equal contributions
external pageThe transcription factors STAT5A/B regulate GM-CSF-mediated granulopoiesiscall_made
Blood, 114: 4721 - 4728
Rieger MA and Schroeder T (2009)
external pageAnalysing cell fate control by cytokines through continuous single cell biochemistrycall_made
Journal of Cellular Biochemistry, 108: 343 - 352
Rieger MA, Smejkal BM and Schroeder T (2009)
external pageImproved prospective identification of megakaryocyte-erythrocyte progenitor cellscall_made
British Journal of Haematology, 144: 448 - 451
Rieger MA and Schroeder T (2009)
external pageInstruction of lineage choice by hematopoietic cytokinescall_made
Cell Cycle, 8: 4019 - 4020
Costa M, Bucholz O, Schroeder T and Götz M (2009)
external pageLate origin of glia-restricted progenitors in the developing mouse cerebral cortexcall_made
Cerebral Cortex, 19 Suppl 1: i135 - 143
2008
Schroeder T (2008)
external pageImaging stem cell driven mammalian regenerationcall_made
Nature, 453: 345 - 351
- Interview (Q&A) of Nature editor Monya Baker with Timm Schroeder about stem cell tracking: external pageMore...call_made
Rieger MA and Schroeder (2008)
external pageExploring hematopoiesis at single cell resolutioncall_made
Cells Tissues Organs, 188: 139-149
Henning K*, Heering J*, Schwanbeck R*, Schroeder T*, Helmbold H, Schäfer H, Deppert W, Kim E and Just U (2008) * equal contribution
external pageNotch1 activation reduces proliferation in multipotent hematopoietic progenitor cell line FDCP-mix through a p53-dependent pathway but Notch1 effects on myeloid and erythroid differentiation are independent of p53call_made
Cell Death and Differentiation, 15: 398-407
Drew EC and Schroeder T (2008)
The Big Brother of Blood: The need for constant video surveillance of individual cells
New Cell Differentiation Research Topics, edited by H Saitama
Nova Science Publishers, 229 - 246
Costa M, Wen G, Lepier A, Schroeder T and Götz M (2008)
external pagePar complex proteins promote proliferating progenitor divisions in the developing mouse cerebral cortexcall_made
Development, 135: 11-22
Schwanbeck R, Schroeder T, Henning K, Kohlhof H, Rieber N, Erfurth ML and Just U (2008)
external pageNotch signalling in embryonic and adult hematopoiesiscall_made
Cells Tissues Organs, 188: 91-102
Rastelli J, Hömig C, Seagal J, Müller W, Hermann A, Rajewsky K and Zimber-Strobl U (2008)
external pageLMP1 signaling can replace CD40 signaling in B cells in vivo and has unique features of inducing class-switsh recombination to IgG1call_made
Blood, 111: 1448-1455
Klier M, Anastasov N, Hermann A, Meindl T, Angermeier D, Raffeld M, Fend F and Quintanilla-Martinez L (2008)
external pageSpecific lentiviral shRNA-mediated knockdown of cyclin D1 in mantle cell lymphoma has minimal effects on cell survival and reveals a regulatory circuit with cyclin D2call_made
Leukemia, 22: 2097-2105
Arakawa H, Kudo H, Batrak V, Caldwell RB, Rieger MA, Ellwart JW and Buerstedde JM (2008)
external pageProtein evolution by hypermutation and selection in the B cell line DT40call_made
Nucleic Acids Research, 36: e1
2007
Schroeder T (2007)
external pageAsymmetric cell division in normal and malignant hematopoietic precursor cellscall_made
Cell Stem Cell, 1: 479-481
Henning K*, Schroeder T*, Schwanbeck R, Rieber N, Bresnick E and Just U (2007) * equal contribution
external pagemNotch1 signaling and erythropoietin cooperate in erythroid differentiation of multipotent progenitor cells and upregulate β-globincall_made
Experimental Hematology, 35: 1321 - 1332
Rieger MA and Schroeder T (2007)
Hämatopoetische Stammzellen
Review (German)
Biospektrum, 3.2007: 254-256
Berninger B, Costa M, Schroeder T, Koch U, Sutor B, Grothe B and Götz M (2007)
external pageFunctional properties of neurons derived from in-vitro reprogrammed postnatal astrogliacall_made
The Journal of Neuroscience, 27: 8654 - 8664
Fürst R, Schroeder T, Eilken HM, Bubik M, Kiemer A, Zahler S and Vollmar A (2007)
external pageMKP-1 represents a novel anti-inflammatory target of glucocorticoids in the human endotheliumcall_made
FASEB Journal, 21: 74-80
2006
Schroeder T*, Meier-Stiegen F, Schwanbeck R, Eilken H, Nishikawa S, Häsler R, Schreiber S, Bornkamm GW, Nishikawa SI and Just U* (2006) * corresponding author
external pageActivated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of developmentcall_made
Mechanisms of Development, 123: 570-579
Cappello S, Attardo A, Wu X, Iwasato T, Itohara S, Wilsch-Brauninger M, Eilken HM, Rieger MA, Schroeder T, HuttnerWB, Brakebusch C and Götz M (2006)
external pageThe Rho-GTPase cdc42 regulates cortical progenitor fate at the apical surfacecall_made
Nature Neuroscience, 9: 1099-1107
Yurugi –Kobayashi Y, Itoh H, Schroeder T, Nakano A, Narazaki G, Kita F, Yanagi K, Hiraoka-Kanie M, Inoue E, Ara T, Nagasawa T, Just U, Nakao K, Nishikawa SI and Yamashita J (2006)
external pageAdrenomedullin/cyclic AMP pathway induces Notch activation and differentiation of arterial endothelial cells from vascular progenitorscall_made
Arteriosclerosis, Thrombosis, and Vascular Biology, 26: 1977-1984
Wolff H, Hartl A, Eilken HM, Hadian K, Ziegler M and Brack-Werner R (2006)
external pageA live-cell assay for simultaneous monitoring of expression and interaction of proteinscall_made
Biotechniques, 41: 688-692
2005
Schroeder T. (2005)
external pageTracking Hematopoiesis at the Single Cell Level.call_made
Hematopoietic Stem Cells V,
Annals of the New York Academy of Sciences, 1044: 201-209
Czuchra A., Wu X., Meyer H., van Hengel J., Schroeder T., Rottner K. and Brakebusch C. (2005)
external pageCdc42 is not essential for filopodium formation, directed migration, cell polarization and mitosis in fibroblastoid cellscall_made
Molecular Biology of the Cell, 16: 4473-4484
Mayer R., Brero A., von Hase J., Schroeder T., Cremer T. and Dietzel S. (2005)
external pageCommon Themes and Cell Type Specific Variations of Higher Order Chromatin Arrangements in the Mousecall_made
BMC Cell Biol, 6: 44
2004
Okita C., Sato M. and Schroeder T. (2004)
external pageGeneration of optimized yellow and red fluorescent proteins with distinct subcellular localization.call_made
Biotechniques, 36: 418-423
2003
Schroeder T. , Fraser S., Ogawa M., Nishikawa S., Oka C., Bornkamm GW., Nishikawa SI., Honjo T. and Just U. (2003)
external pageRecombination signal sequence-binding protein Jk alters mesodermal cell fate decisions by suppressing cardiomyogenesis.call_made
PNAS, 100: 4018-4023
Schroeder T. , Kohlhof H., Rieber N. and Just U. (2003)
external pageNotch signaling induces multilineage myeloid differentiation and up-regulates PU.1 expression.call_made
The Journal of Immunology, 170: 5538-5548
McIvor Z., Hein S., Fiegler H., Schroeder T., Stocking C., Just U. and Cross M. (2003)
external pageTransient expression of PU.1 commits multipotent progenitors to a myeloid fate whereas continued expression favors macrophage over granulocyte differentiation.call_made
Experimental Hematology, 31: 39-47
Mathys S., Schroeder T., Ellwart J., Koszinowski U. , Messerle M. and Just U. (2003)
external pageDendritic cells under influence of mouse cytomegalovirus have a physiologic dual role: to initiate and to restrict T cell activation.call_made
The Journal of Infectious Diseases, 187: 988-999
2000
Schroeder, T. and Just, U. (2000)
external pageNotch signalling via RBP-J promotes myeloid differentiation.call_made
EMBO Journal, 19: 2558-2568
Schroeder, T. and Just, U. (2000)
external pagemNotch1 signaling reduces proliferation of myeloid progenitor cells by altering cell-cycle kinetics.call_made
Experimental Hematology, 28: 1206-1213
Schroeder, T. , Lange, C., Strehl, J. and Just, U. (2000)
external pageGeneration of functionally mature dendritic cells from the multipotential stem cell line FDCP-mix.call_made
British Journal of Haematology, 111: 890-897
1999
Drzeniek, Z., Stocker, G., Siebertz, B., Just, U., Schroeder, T., Ostertag, W. and Haubeck, H.D. (1999)
external pageHeparan sulfate proteoglycan expression is induced during early erythroid differentiation of multipotent hematopoietic stem cells.call_made
Blood, 93: 2884-2897