Research
We are involved in grant-funded projects with several research groups at ETH Zurich and the University of Basel.
The extra funding enables us to extend our expertise and technical infrastructure and leverages cutting-edge research initiatives which may reach out beyond the standard support settings.
In the recent years we were able to hire additional staff members and install equipment for increasing sample throughput and the introduction of single-cell genomics applications.
Third party funded research
(project period: 2013-2017) We were part of this collaborative project funded by external pageSystemsX.ch in which we addressed stem cell heterogeneity during the development of cerebral cortex and the signaling pathways controlling their fate to predict and model the processes of cortical development.
external pageRead more about NeuroStemX
(project period: 2014-2018) Drug-resistant organisms endanger the successful treatment of tuberculosis. However, many factors and mechanisms leading to the development and spread of resistance are still largely unknown. The aim of this collaborative project funded by external pageSystemsX.ch was to acquire new knowledge in this area and to develop an extensive model to simulate the involved processes. external pageRead more about TbX
(project period: 2012-2016) In this collaborative external pageiPhD project with Niko Beerenwinkel (ETH Zurich) and Holger Moch (University Hospital Zurich) we explored the heterogeneity within tumors, specifically we were interested in Renal Cell Carcinoma. external pageOur project featured in X-Letter 32 "Do cancer cells cooperate?" Results have been published in external pagePLoS Computational Biology and external pageCancers.
ETH Zurich funded research
We successfully accomplished a long standing research project that started in Renato Paro's Epigenomics group at D-BSSE. In close cooperation with Matthias Gstaiger we comprehensively characterized the Polycomb interactome of a human cell line. The study has been published and highlighted as cover story in Cell Reports. external pageLink to publication