Aurellia Galliot
Aurellia Galliot
Student / Programme Doctorate at D-BSSE
I am part of the EU NEWmRNA project which aims to rethink the synthetic biology of mRNAs in bacteria, including in vivo large-scale production of mRNAs for purposes such as vaccination or gene therapy. The goal of my thesis is to increase the production yield of “cloaked” (protected) mRNAs out of E. coli by preventing their degradation, and then to develop “decloaking” for isolation.
Publications
external page NOseq: amplicon sequencing evaluation method for RNA m6A sites after chemical deamination. Werner S, Galliot A, Pichot F, Kemmer T, Marchand V, Sednev MV, Lence T, Roignant JY, König J, Höbartner C, Motorin Y, Hildebrandt A, Helm M. Nucleic Acids Res (2021). doi: 10.1093/nar/gkaa1173
external page Determination of enrichment factors for modified RNA in MeRIP experiments. Slama K, Galliot A, Weichmann F, Hertler J, Feederle R, Meister G, Helm M. Methods (2019). doi: 10.1016/j.ymeth.2018.10.020
external page Absolute Quantification of Noncoding RNA by Microscale Thermophoresis. Jacob D, Thüring K, Galliot A, Marchand V, Galvanin A, Ciftci A, Scharmann K, Stock M, Roignant JY, Leidel SA, Motorin Y, Schaffrath R, Klassen R, Helm M. Angew Chem Int Ed Engl (2019). doi: 10.1002/anie.201814377
external page Effects of oxygenation on the intercalation of 1,10-phenanthroline-5,6/4,7-dione between DNA base pairs: a computational study. Galliot A, Gil A, Calhorda MJ. Phys Chem Chem Phys (2017). doi: 10.1039/c7cp00532f