Partners

Synthetic Biology of mRNA

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Given the diverse role of mRNA in major life science applications from vaccination via gene therapy, chemistry, and diagnostics to pest control in agriculture there is a huge opportunity to improve the outcome of medical therapies, broaden chemical catalysis, advance medical diagnostics, and reduce the human footprint in agriculture. With a focus on medical applications, NEWmRNA proposes to follow a synthetic biology approach to redraw and transform biological mass production of mRNAs.
In the course of the project, we will implement a novel cellular assay to rapidly assess the impact of non-canonical forms of mRNA on translation and cellular signalling and introduce crucial steps for industrial-scale production of mRNA.
The project has received funding from the European Union’s Horizon 2020 research and innovation programme (Future Emerging Technologies (FET) Open programme) under grant agreement No. 965135.

More information is available at the project’s external page web page and external page twitter account.

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NCCR Molecular Systems Engineering

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The Swiss National Science Foundation (SNSF) refers to research projects of great importance to science, economy and society as „National Centres of Competence in Research“ (NCCR). A board of experts carefully selects proposals from various universities and/or researchers and funds the most relevant and promising over a maximum period of 12 years.

The NCCR Molecular Systems Engineering is set to redefine the traditional view science has on individual molecular modules. The main goal is to develop new engineering principles that reveal how they can be combined to form working molecular production lines – so called molecular factories. The findings in this complex research are key to meet future economic and technical challenges.

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EmPowerPutida

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The European Union’s H2020 “EmPowerPutida” project brings together nine partners from academia and industry, focusing on the development of novel bioprocesses for the sustainable production of bulk and specialty chemicals.

While starting out with basic research in the partner universities, mainly working on the optimization of the chassis organism Pseudomonas putida and the co-development of underlying technologies utilizing the toolbox of synthetic biology, the industrial partners ensure a subsequent process scale-up and the assessment of the microbial catalysts under industrially relevant conditions.

More information is available at the external page project’s web page and external page twitter account.

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