BEL News

Firing patterns in human and murine brain organoids do not arise in experience-dependent manner, but are constrained by preconfigured architecture established during neurodevelopment.

Open microfluidic platform developed that enables co-culturing of 3D tissue spheroids and circulating cells over days. Fluid flow to recirculate cells and promote distribution of cell-secreted factors and nutrients established by device tilting.

Manon Murdeu received Gerhard Zbinden Early Career Award (ECA) and IN2TOX speciality section award for best poster presentation at EUROTOX 2025 in Athens for contribution "Human-based placenta-embryo chip for developmental toxicity assessment of nanoparticles and drugs."

New comprehensive review article "Advances in large-scale electrophysiology with high-density microelectrode arrays" written in group effort and published in journal Lab on a Chip by Royal Society of Chemistry.

To perceive events on unified time scale, synchronization in human visual system begins in fovea centralis - a retinal region used for reading and recognizing faces - as could be shown by combining HD-MEA and behavioral experiments with modeling.  

Formation of neuronal networks in the brain is based on homophilic generative wiring principle, in which neurons form connections to other neurons that are spatially proximal and have similar connectivity patterns.
 

Swiss 3Rs Young Investigator Award by the Swiss 3R Competence Center to Manon Murdeu for her work on "Human-based placenta-embryo chip for developmental toxicity assessment of drugs, chemicals and nanoparticles."

Rachel Sava, who did her Master thesis in our group, received ETH medal for her thesis and Willi Studer prize as one of the best students in the Master curriculum Biotechnology at D-BSSE.

Novel multifunctional CMOS microelectrode array has been integrated into an open microfluidic system. The array can be used in hanging-drop mode for in situ microtissue readouts and in standing-drop mode like a conventional microelectrode array.