Cybergenetic control systems advance synthetic biology
The design of biomolecular control systems facilitates the precise and robust regulation of biological processes. Researchers from the group of Mustafa Khammash now present a synthetic biology roadmap for designing genetic feedback controllers to precisely steer cellular dynamics, enhancing performance while reducing stochastic noise. These high-performance cybergenetic control systems will be the basis for biotechnological applications in industry and health care.
Find original publication:
Filo, M, Kumar, S and M Khammash (2022) external page A hierarchy of biomolecular proportional-integral-derivative feedback controllers for robust perfect adaptation and dynamic performance. Nature Communications 13, 2119. https://doi.org/10.1038/s41467-022-29640-7
Learn about the Control Theory and Systems Biology Lab led by Mustafa Khammash.