Novel light-sensitive devices for dynamic information processing in living cells
Cells live in constantly changing environments to which they react by decoding environmental signals to induce a suitable gene expression that triggers a targeted response. Using light-responsive regulators of gene expression, researchers from the group of Mustafa Khammash now built novel synthetic signal processing circuits in living cells that decode information from dynamic light signals. These circuits provide novel tools for use in biotechnological applications.
Find original publication:
Benzinger, D, S Ovinnikov, and M Khammash (2022) Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression. Cell Systems, external page https://doi.org/10.1016/j.cels.2022.02.004
Learn about research in the Control Theory and Systems Biology Lab led by Mustafa Khammash.