New insights on eosinophils fill gaps in single cell atlases

Eosinophils are a type of white blood cells involved in the control of intestinal inflammation. Yet, eosinophils have been difficult to study and so far have remained invisible to single-cell transcriptomics, a tool used to construct tissue atlases in health and disease. A Nature study co-led by Costanza Borrelli from the Moor lab and colleagues at the University of Zurich, now provides novel insights into the biology of this cell type.

Find original article in Nature:

Gurtner, A, C Borrelli, I Gonzalez-Perez, K Bach, I E Acar, N G Núñez, D Crepaz, K Handler, V P Vu, A Lafzi, K Stirm, D Raju, J Gschwend, K Basler, Ch Schneider, E Slack, T Valenta, B Becher, Ph Krebs, A E Moor and I C Arnold (2022) external pageActive eosinophils regulate host defense and immune responses in colitis. Nature, https://doi.org/10.1038/s41586-022-05628-7

 

Learn about research in the Systems Physiology lab led by Andreas Moor.

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